ANAPC11 (Anaphase Promoting Complex Subunit 11, ANAPC11)
Short Description: Probably catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin- protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin- conjugating E2 enzymes, it catalyzes the formation of protein- ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication. APC11 is required to recruit the ubiquitin- conjugating enzyme E2 to the APC/C.
More information related to gene ANAPC11.
More information related to gene ANAPC11.
Products related to ANAPC11 Gene:
Recommended next Filters:
93 results :
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Anaphase Promoting Complex Subunit 11 (ANAPC11)
- NCBI Accession:
- NM_016476
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Anaphase Promoting Complex Subunit 11 (ANAPC11)
- NCBI Accession:
- NM_016476
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Anaphase Promoting Complex Subunit 11 (ANAPC11)
- NCBI Accession:
- NM_001126082
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Anaphase Promoting Complex Subunit 11 (ANAPC11)
- NCBI Accession:
- NM_001038230
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Anaphase Promoting Complex Subunit 11 (ANAPC11)
- NCBI Accession:
- NM_001002247
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Anaphase Promoting Complex Subunit 11 (ANAPC11)
- NCBI Accession:
- NM_016476
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Anaphase Promoting Complex Subunit 11 (ANAPC11)
- NCBI Accession:
- NM_016476
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Anaphase Promoting Complex Subunit 11 (ANAPC11)
- NCBI Accession:
- NM_016476
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Anaphase Promoting Complex Subunit 11 (ANAPC11)
- NCBI Accession:
- NM_016476
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-His
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- His tag
- Expression:
- Stable, Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Anaphase Promoting Complex Subunit 11 (ANAPC11)
- NCBI Accession:
- NM_001038230
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Synonyms and alternative names related to ANAPC11
- anaphase promoting complex subunit 11 (ANAPC11)
- anaphase promoting complex subunit 11 L homeolog (anapc11.L)
- anaphase promoting complex subunit 11 (anapc11)
- anaphase promoting complex subunit 11 (Anapc11)
- anaphase-promoting complex/cyclosome 11 (APC11)
- anaphase promoting complex subunit 11 (APC11)
- anaphase-promoting complex subunit Apc11 (apc11)
- anaphase promoting complex subunit 11 (CAALFM_CR10610CA)
- ubiquitin-protein ligase Anaphase Promoting Complex (APC11)
- hypothetical protein (APC11)
- predicted protein (APC11)
- anaphase-promoting complex subunit 11 (LOC9320604)
- anaphase promoting complex subunit 11 (LOC692923)
- APC11 anaphase promoting complex subunit 11 homolog (yeast) (anapc11)
- 1110011I19Rik
- anapc11
- anaphase-promoting complex/cyclosome 11
- APC11
- Apc11p
- DDBDRAFT_0187183
- DDBDRAFT_0231277
- DDB_0187183
- DDB_0231277
- F10A16.17
- F10A16_17
- R75218
- RGD1561880
- si:dkey-237i9.4
- zgc:153671
Gene-IDs for different species
Protein level used designations for ANAPC11
- APC11 anaphase promoting complex subunit 11 homolog
- anaphase promoting complex subunit 11 (yeast APC11 homolog)
- anaphase-promoting complex subunit 11
- cyclosome subunit 11
- hepatocellular carcinoma-associated RING finger protein
- anaphase promoting complex subunit 11
- anaphase promoting complex subunit 11 homolog
- Apc11p
- Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
- anaphase-promoting complex subunit Apc11
- potential anaphase-promoting complex subunit Apc11
- ubiquitin-protein ligase Anaphase Promoting Complex
- hypothetical protein
- anaphase-promoting complex/cyclosome 11
- APC11
Proteomics products related to ANAPC11 Gene
Other products related to ANAPC11 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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