APOB (Apolipoprotein B, APOB)

Short Description: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008].
More information related to gene APOB.
Products related to APOB Gene:
74 Products
Type
  • 69
  • 5
Species
  • 31
  • 22
  • 19
  • 2
Application
  • 32
  • 22
  • 17
  • 15
Fusion tag
  • 27
  • 9
  • 8
  • 8
  • 5
Vector Backbone
  • 6
  • 6
  • 6
  • 4
  • 3
Vector
  • 24
  • 21
  • 12
  • 6
  • 5
Insert
  • 28
  • 17
  • 9
  • 7
  • 6
Oligo-Type
  • 5
Resistance Gene
  • 33
  • 24
  • 8
  • 4
  • 2
Expression Type
  • 66
  • 44
Selectable Marker
  • 24
  • 22
Promoter
  • 26
  • 20
  • 12
  • 8
  • 6
Format
  • 27
  • 23
  • 17
  • 7

Type:
cDNA
Application:
Cloning
Gene:
Apolipoprotein B (APOB)
Gene ID:
379475 (Xenopus laevis, APOB)
Synonyms:
APOB, Apob
Vector type:
Cloning Vector
Vector backbone:
pDNR-LIB
Resistance Gene:
Chloramphenicol

Sequencing Primer:
  • T7
  • M13(-21)
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN4040996
$118.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Cloning
Gene:
Apolipoprotein B (APOB)
Gene ID:
379475 (Xenopus laevis, APOB)
Synonyms:
APOB, Apob
Vector type:
Cloning Vector
Vector backbone:
pDNR-LIB
Resistance Gene:
Chloramphenicol

Sequencing Primer:
  • T7
  • M13(-21)
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN4040997
$162.44
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Protein Expression
Gene:
Apolipoprotein B (APOB)
Species:
Human
Synonyms:
APOB, Apob
Insert length:
2478 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-N-D-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag,His tag
Expression:
Stable, Transient

Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4559883
$300.00
500 ng
Plus shipping costs $45.00
Delivery in 11 to 21 Business Days

Type:
cDNA
Application:
Cloning
Gene:
Apolipoprotein B (APOB)
Species:
Human
Synonyms:
APOB, Apob
Insert length:
2478 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient

Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4697469
$300.00
500 ng
Plus shipping costs $45.00
Delivery in 11 to 21 Business Days

Type:
cDNA
Application:
Cloning
Gene:
Apolipoprotein B (APOB)
Species:
Human
Synonyms:
APOB, Apob
Insert length:
2478 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient

Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4826598
$300.00
500 ng
Plus shipping costs $45.00
Delivery in 11 to 21 Business Days

Type:
cDNA
Application:
Protein Expression
Gene:
Apolipoprotein B (APOB)
Species:
Human
Synonyms:
APOB, Apob
Insert length:
2478 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-N-D-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag,HA tag
Expression:
Stable, Transient

Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4498673
$300.00
500 ng
Plus shipping costs $45.00
Delivery in 11 to 21 Business Days

Type:
ORF
Application:
Protein Expression
Gene:
Apolipoprotein B (APOB)
Gene ID:
338 (Human, APOB)
Synonyms:
APOB, Apob
Vector type:
Gateway Cloning Vector
Vector backbone:
pENTR223-1-LC
Resistance Gene:
Spectinomycin

Sequencing Primer:
  • T7
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3427586
$308.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Apolipoprotein B (APOB)
NCBI Accession:
NM_000384
Species:
Human
Synonyms:
APOB, Apob
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of APOB
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5163398
$420.00
300 μL
Plus shipping costs $45.00 and $22.00 dry ice
Available

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Apolipoprotein B (APOB)
NCBI Accession:
NM_019287
Species:
Rat (Rattus)
Synonyms:
APOB, Apob
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Apob
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5163402
$420.00
300 μL
Plus shipping costs $45.00 and $22.00 dry ice
Available

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Apolipoprotein B (APOB)
NCBI Accession:
NM_009693
Species:
Mouse (Murine)
Synonyms:
APOB, Apob
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Apob
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5163400
$420.00
300 μL
Plus shipping costs $45.00 and $22.00 dry ice
Available

Application:
RNA Interference
Gene:
Apolipoprotein B
Species:
Mouse (Murine)
Synonyms:
FLDB, LDLCQ4, Ac1-060, Apo B-100, ApoB-100, ApoB-48, AI315052, apob-100, apob-48, APOB-100, ApoB(100), APOB
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • Apob (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3350532
$430.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Application:
RNA Interference
Gene:
Apolipoprotein B
Species:
Human
Synonyms:
FLDB, LDLCQ4, Ac1-060, Apo B-100, ApoB-100, ApoB-48, AI315052, apob-100, apob-48, APOB-100, ApoB(100), APOB
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • APOB (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3340034
$430.00
1 kit
Plus shipping costs $45.00
Delivery in 4 to 8 Business Days

Type:
gRNA + gRNA
Application:
Genome Editing with Engineered Nucleases
Gene:
Apolipoprotein B (APOB)
Gene ID:
338 (Human, APOB)
Synonyms:
APOB, Apob
Vector type:
Lentiviral Vector
Vector backbone:
pCLIP-dual-SFFV-ZsGreen
Resistance Gene:
Ampicillin, Zeocin
Selection Marker:
Puromycin
Promoter:
SFFV Promoter, U6 Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Viral particles:
ABIN5054477

Components:
- Two vectors containing two gRNAs in each vector
- Negative control
- Available as bacterial glycerol stocks or viral particles
- Cas9 expression vectors can be purchased separately
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN5035532
$503.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
ORF
Application:
Cloning
Gene:
Apolipoprotein B (APOB)
Species:
Human
Synonyms:
APOB, Apob
Insert length:
2478 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient

Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Catalog No. ABIN5763524
$511.00
1 μg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days

Application:
RNA Interference
Gene:
Apolipoprotein B
Gene ID:
338 (Human, APOB)
Synonyms:
FLDB, LDLCQ4, Ac1-060, Apo B-100, ApoB-100, ApoB-48, AI315052, apob-100, apob-48, APOB-100, ApoB(100), APOB
Purification:
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Components:
This product is provided as two 5 nmol vials (10 nmol), three 5 nmol vials (15 nmol) or 2x three 5 nmol vials (30 nmol) of lyophilized siRNA oligo duplexes. Each vial contains slightly different sequences to ensure full knockout of the gene. Each vial contains slightly different sequences to ensure full knockout of the gene. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. The siRNA oligos are also chemically modified (2'-OMe) for increased stability and enhanced knockdown in vitro and in vivo.
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5801303
$511.63
Plus shipping costs $45.00
Delivery in 16 to 26 Business Days

Application:
RNA Interference
Gene:
Apolipoprotein B
Gene ID:
54225 (Rat (Rattus), APOB)
Synonyms:
FLDB, LDLCQ4, Ac1-060, Apo B-100, ApoB-100, ApoB-48, AI315052, apob-100, apob-48, APOB-100, ApoB(100), APOB
Purification:
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Components:
This product is provided as two 5 nmol vials (10 nmol), three 5 nmol vials (15 nmol) or 2x three 5 nmol vials (30 nmol) of lyophilized siRNA oligo duplexes. Each vial contains slightly different sequences to ensure full knockout of the gene. Each vial contains slightly different sequences to ensure full knockout of the gene. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. The siRNA oligos are also chemically modified (2'-OMe) for increased stability and enhanced knockdown in vitro and in vivo.
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5801304
$511.63
Plus shipping costs $45.00
Delivery in 16 to 26 Business Days

Application:
RNA Interference
Gene:
Apolipoprotein B
Gene ID:
238055 (Mouse (Murine), APOB)
Synonyms:
FLDB, LDLCQ4, Ac1-060, Apo B-100, ApoB-100, ApoB-48, AI315052, apob-100, apob-48, APOB-100, ApoB(100), APOB
Purification:
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Components:
This product is provided as two 5 nmol vials (10 nmol), three 5 nmol vials (15 nmol) or 2x three 5 nmol vials (30 nmol) of lyophilized siRNA oligo duplexes. Each vial contains slightly different sequences to ensure full knockout of the gene. Each vial contains slightly different sequences to ensure full knockout of the gene. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. The siRNA oligos are also chemically modified (2'-OMe) for increased stability and enhanced knockdown in vitro and in vivo.
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5801305
$511.63
Plus shipping costs $45.00
Delivery in 16 to 26 Business Days

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Apolipoprotein B (APOB)
NCBI Accession:
NM_000384
Species:
Human
Synonyms:
APOB, Apob
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of APOB
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5278983
$520.00
300 μL
Plus shipping costs $45.00 and $22.00 dry ice
Available

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Apolipoprotein B (APOB)
NCBI Accession:
NM_009693
Species:
Mouse (Murine)
Synonyms:
APOB, Apob
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Apob
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5278985
$520.00
300 μL
Plus shipping costs $45.00 and $22.00 dry ice
Available

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Apolipoprotein B (APOB)
NCBI Accession:
NM_019287
Species:
Rat (Rattus)
Synonyms:
APOB, Apob
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Apob
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5278987
$520.00
300 μL
Plus shipping costs $45.00 and $22.00 dry ice
Available
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  • 1

Synonyms and alternative names related to APOB

  • apolipoprotein B (APOB)
  • apolipoprotein B (Apob)
  • Ac1-060
  • AI315052
  • APOB
  • ApoB(100)
  • ApoB-48
  • apob-48
  • Apo B-100
  • ApoB-100
  • apob-100
  • APOB-100
  • FLDB
  • LDLCQ4

Gene-IDs for different species

GENE IDSPECIES
338 Homo sapiens
54225 Rattus norvegicus
238055 Mus musculus
494004 Bos taurus
702937 Macaca mulatta
100009101 Oryctolagus cuniculus
100523371 Sus scrofa
396535 Gallus gallus
100725937 Cavia porcellus
475680 Canis lupus familiaris
101107590 Ovis aries

Protein level used designations for APOB

  • apo B-100
  • apoB-100
  • apoB-48
  • apolipoprotein B (including Ag(x) antigen)
  • apolipoprotein B-100
  • apolipoprotein B48
  • mutant Apo B 100
  • apolipoprotein B PI
  • apolipoprotein B-48
  • apolipoprotein B
Other products related to APOB such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com