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ATXN7L2 (Ataxin 7-Like 2, ATXN7L2)

Short Description: The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the 'pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. This locus has been mapped to chromosome 3, and it has been determined that the diseased allele associated with spinocerebellar ataxia-7 contains 38-130 CAG repeats (near the N-terminus), compared to 7-17 in the normal allele. The encoded protein is a component of the SPT3/TAF9/GCN5 acetyltransferase (STAGA) and TBP-free TAF-containing (TFTC) chromatin remodeling complexes, and it thus plays a role in transcriptional regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010].
More information related to gene ATXN7L2.

Products related to ATXN7L2 Gene:

61 results:

ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Ataxin 7-Like 2 (ATXN7L2)
NCBI Accession:
NM_153340
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5743558
$511.00
Plus shipping costs $45.00
Shipping to: United States
Delivery in 11 to 21 Business Days
cDNA PExp Mammalian Expression Vector pPM-N-D-C-HA Kanamycin CMV Promoter DYKDDDDK Tag,HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Ataxin 7-Like 2 (ATXN7L2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-N-D-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag,HA tag
Expression:
Stable, Transient
Catalog No. ABIN4499114
$571.54
Plus shipping costs $45.00
Shipping to: United States
Delivery in 11 to 21 Business Days
cDNA PExp Mammalian Expression Vector pPM-N-D-C-His Kanamycin CMV Promoter DYKDDDDK Tag,His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Ataxin 7-Like 2 (ATXN7L2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-N-D-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag,His tag
Expression:
Stable, Transient
Catalog No. ABIN4560323
$571.54
Plus shipping costs $45.00
Shipping to: United States
Delivery in 11 to 21 Business Days
gRNA + Cas9 GEEN, PExp Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Ataxin 7-Like 2 (ATXN7L2)
NCBI Accession:
NM_153340
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5239977
$685.77
Plus shipping costs $45.00 and $20.00 dry ice
Shipping to: United States
Delivery in 11 to 21 Business Days
gRNA + Cas9 GEEN, PExp Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Ataxin 7-Like 2 (ATXN7L2)
NCBI Accession:
NM_175183
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5239979
$685.77
Plus shipping costs $45.00 and $20.00 dry ice
Shipping to: United States
Delivery in 11 to 21 Business Days
gRNA GEEN, PExp Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Ataxin 7-Like 2 (ATXN7L2)
NCBI Accession:
NM_153340
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5124574
$555.00
Plus shipping costs $45.00 and $20.00 dry ice
Shipping to: United States
Delivery in 11 to 21 Business Days
gRNA GEEN, PExp Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Ataxin 7-Like 2 (ATXN7L2)
NCBI Accession:
NM_175183
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5124576
$555.00
Plus shipping costs $45.00 and $20.00 dry ice
Shipping to: United States
Delivery in 11 to 21 Business Days
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Ataxin 7-Like 2 (ATXN7L2)
NCBI Accession:
NM_175183
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5743559
$651.00
Plus shipping costs $45.00
Shipping to: United States
Delivery in 11 to 21 Business Days
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Ataxin 7-Like 2 (ATXN7L2)
NCBI Accession:
NM_153340
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4421898
$900.00
Plus shipping costs $45.00
Shipping to: United States
Delivery in 11 to 21 Business Days
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Ataxin 7-Like 2 (ATXN7L2)
NCBI Accession:
NM_153340
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4486984
$900.00
Plus shipping costs $45.00
Shipping to: United States
Delivery in 11 to 21 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • transOMIC technologies
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Zebrafish (Danio rerio)
    • Cow
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • ZsGreen
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag,HA tag
    • DYKDDDDK Tag,His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pZIP-mCMV-ZsGreen
    • pME18S-FL3
    • pCLIP-dual-SFFV-ZsGreen
    • pCMV-SPORT6
    • pCR4-TOPO
    • pCas-Guide
    • pExpress-1
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pPB-C-His
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pPM-N-D-C-HA
    • pPM-N-D-C-His
    • pRS
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Cloning Vector
    • Retroviral Vector
  • Insert
    • cDNA
    • shRNA
    • ORF
    • gRNA + Cas9
    • gRNA
    • gRNA + gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
    • Zeocin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • Enhanced CMV Promoter
    • T7 Promoter
    • SFFV Promoter
    • PGK Promoter
    • mCMV Promoter
  • Format
    • Liquid
    • Lyophilized
    • Viral Particles
    • Glycerol Stock

Synonyms and alternative names related to ATXN7L2

  • ataxin 7-like 2 (Atxn7l2)
  • ataxin 7 like 2 (ATXN7L2)
  • ataxin 7-like 2b (atxn7l2b)
  • ataxin 7-like 2a (atxn7l2a)
  • ataxin 7 like 2 (Atxn7l2)
  • 2610528J18Rik
  • atxn7l2
  • RGD1307047
  • wu:fi32b11
  • wu:fi36e12
  • zgc:92454
  • zgc:136546

Gene-IDs for different species

Protein level used designations for ATXN7L2

  • ataxin-7-like protein 2
  • mFLJ00381 protein
  • ataxin 7-like 1
  • ataxin 7-like 2
  • fi32b11
Other products related to ATXN7L2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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