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BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator), BRE)

Short Description: Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity and modulating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin (By similarity).
More information related to gene BRE.

Products related to BRE Gene:

78 results :

Human BRE ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5745035
Datasheet
Catalog No. ABIN5745035
Type:
ORF
Application:
Cloning
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
Species:
Human
Synonyms:
babam2, BABAM2, Babam2, BRE, babam2.L
Insert length:
1152 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human BRE cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4472683
Datasheet
Catalog No. ABIN4472683
Type:
cDNA
Application:
Protein Expression
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
Species:
Human
Synonyms:
babam2, BABAM2, Babam2, BRE, babam2.L
Insert length:
1152 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat BRE CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
NCBI Accession:
NM_199270
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5242707
Datasheet
Catalog No. ABIN5242707
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
NCBI Accession:
NM_199270
Species:
Rat
Synonyms:
babam2, BABAM2, Babam2, BRE, babam2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Bre
Format:
Viral Particles
Storage:
-80 °C
Mouse BRE CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
NCBI Accession:
NM_144541
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5242705
Datasheet
Catalog No. ABIN5242705
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
NCBI Accession:
NM_144541
Species:
Mouse
Synonyms:
babam2, BABAM2, Babam2, BRE, babam2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Bre
Format:
Viral Particles
Storage:
-80 °C
Human BRE CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
NCBI Accession:
NM_199191
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5242703
Datasheet
Catalog No. ABIN5242703
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
NCBI Accession:
NM_199191
Species:
Human
Synonyms:
babam2, BABAM2, Babam2, BRE, babam2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of BRE
Format:
Viral Particles
Storage:
-80 °C
Rat BRE CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
NCBI Accession:
NM_199270
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5127282
Datasheet
Catalog No. ABIN5127282
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
NCBI Accession:
NM_199270
Species:
Rat
Synonyms:
babam2, BABAM2, Babam2, BRE, babam2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Bre
Format:
Viral Particles
Storage:
-80 °C
Mouse BRE CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
NCBI Accession:
NM_144541
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5127280
Datasheet
Catalog No. ABIN5127280
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
NCBI Accession:
NM_144541
Species:
Mouse
Synonyms:
babam2, BABAM2, Babam2, BRE, babam2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Bre
Format:
Viral Particles
Storage:
-80 °C
Human BRE CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
NCBI Accession:
NM_199191
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5127278
Datasheet
Catalog No. ABIN5127278
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
NCBI Accession:
NM_199191
Species:
Human
Synonyms:
babam2, BABAM2, Babam2, BRE, babam2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of BRE
Format:
Viral Particles
Storage:
-80 °C
Human BRE cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4759058
Datasheet
Catalog No. ABIN4759058
Type:
cDNA
Application:
Cloning
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
Species:
Human
Synonyms:
babam2, BABAM2, Babam2, BRE, babam2.L
Insert length:
1152 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human BRE cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4827337
Datasheet
Catalog No. ABIN4827337
Type:
cDNA
Application:
Cloning
Gene:
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE)
Species:
Human
Synonyms:
babam2, BABAM2, Babam2, BRE, babam2.L
Insert length:
1152 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pcDNA3.1+C-(K)-DYK
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCas-Guide
    • pCMV6-AC
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Spectinomycin
    • Chloramphenicol
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to BRE

  • BRISC and BRCA1 A complex member 2 (babam2)
  • BRISC and BRCA1 A complex member 2 (BABAM2)
  • BRISC and BRCA1 A complex member 2 (Babam2)
  • brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE)
  • BRISC and BRCA1 A complex member 2 L homeolog (babam2.L)
  • 6030405P19Rik
  • AI429776
  • B830038C02Rik
  • brcc4
  • BRCC4
  • brcc45
  • BRCC45
  • BRE
  • im:7141046
  • LOC100231620
  • zgc:110368

Gene-IDs for different species

Protein level used designations for BRE

  • BRCA1-A complex subunit BRE
  • BRCA1/BRCA2-containing complex subunit 45
  • Brain and reproductive organ-expressed protein
  • brain and reproductive organ-expressed (TNFRSF1A modulator)
  • BRCA1-A complex subunit BRE-like
  • BRCA1/BRCA2-containing complex, subunit 4
  • brain and reproductive organ-expressed protein
Other products related to BRE such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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