C3 (Complement Component 3, C3)

Short Description: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection. [provided by RefSeq, Feb 2009].
More information related to gene C3.
Products related to C3 Gene:
88 Products
Data Quality
  • 1
Type
  • 82
  • 6
Species
  • 36
  • 26
  • 22
  • 2
  • 2
Application
  • 44
  • 26
  • 25
  • 16
Fusion tag
  • 38
  • 11
  • 9
  • 6
  • 5
Vector Backbone
  • 10
  • 6
  • 6
  • 4
  • 4
Vector
  • 35
  • 23
  • 12
  • 9
  • 3
Insert
  • 38
  • 19
  • 9
  • 8
  • 6
Oligo-Type
  • 6
Resistance Gene
  • 37
  • 34
  • 8
  • 3
  • 2
Expression Type
  • 82
  • 48
Selectable Marker
  • 26
  • 24
Promoter
  • 31
  • 21
  • 16
  • 12
  • 8
Format
  • 32
  • 27
  • 15
  • 14

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
Complement Component 3 (C3)
Gene ID:
718 (Human, C3)
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Mammalian Expression Vector
Vector backbone:
pTCN
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • 3-1291
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN4098034
$107.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
Complement Component 3 (C3)
Gene ID:
398666 (Xenopus laevis, C3)
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV-SPORT6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • T7
  • Sp6
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3845910
$118.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
Complement Component 3 (C3)
Gene ID:
718 (Human, C3)
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV-SPORT6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • T7
  • Sp6
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3803302
$118.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
Complement Component 3 (C3)
Gene ID:
718 (Human, C3)
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV-SPORT6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • T7
  • Sp6
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3803303
$118.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
Complement Component 3 (C3)
Gene ID:
280677 (Cow (Bovine), C3)
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV-SPORT6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • T7
  • Sp6
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3838294
$118.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
Complement Component 3 (C3)
Gene ID:
12266 (Mouse (Murine), C3)
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV-SPORT6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • T7
  • Sp6
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3807840
$118.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
Complement Component 3 (C3)
Gene ID:
398666 (Xenopus laevis, C3)
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV-SPORT6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • T7
  • Sp6
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3845911
$162.44
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
Complement Component 3 (C3)
Gene ID:
718 (Human, C3)
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV-SPORT6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • T7
  • Sp6
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3803305
$162.44
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
Complement Component 3 (C3)
Gene ID:
718 (Human, C3)
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV-SPORT6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • T7
  • Sp6
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3803304
$162.44
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
Complement Component 3 (C3)
Gene ID:
280677 (Cow (Bovine), C3)
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV-SPORT6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • T7
  • Sp6
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3838292
$162.44
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
Complement Component 3 (C3)
Gene ID:
12266 (Mouse (Murine), C3)
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV-SPORT6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • T7
  • Sp6
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3807841
$162.44
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Application:
RNA Interference
Gene:
Complement Component 3
Species:
Mouse (Murine)
Synonyms:
AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, AI255234, HSE-MSF, Plp, C3, C3-1, sb:cb26, si:dkey-76b14.4, wu:fi34b03, wu:fj86e11, C3d, asp, cpamd1, c3
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • C3 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3349954
$420.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Application:
RNA Interference
Gene:
Complement Component 3
Species:
Human
Synonyms:
AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, AI255234, HSE-MSF, Plp, C3, C3-1, sb:cb26, si:dkey-76b14.4, wu:fi34b03, wu:fj86e11, C3d, asp, cpamd1, c3
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • C3 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Publications
  • Long, Cao, Bian, Li: "C3a Increases VEGF and Decreases PEDF mRNA Levels in Human Retinal Pigment Epithelial Cells." in: BioMed research international, Vol. 2016, Issue , pp. 6958752, 2016 (Pubmed)
Catalog No. ABIN3340293
$420.00
1 kit
Plus shipping costs $45.00
Delivery in 4 to 8 Business Days

Application:
RNA Interference
Gene:
Complement Component 3
Species:
Rat (Rattus)
Synonyms:
AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, AI255234, HSE-MSF, Plp, C3, C3-1, sb:cb26, si:dkey-76b14.4, wu:fi34b03, wu:fj86e11, C3d, asp, cpamd1, c3
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • C3 (Rat) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3357588
$420.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Complement Component 3 (C3)
NCBI Accession:
NM_000064
Species:
Human
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of C3
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5084732
$420.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Complement Component 3 (C3)
NCBI Accession:
NM_009778
Species:
Mouse (Murine)
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of C3
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5084734
$420.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Complement Component 3 (C3)
NCBI Accession:
NM_016994
Species:
Rat (Rattus)
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of C3
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5084736
$420.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available

Type:
gRNA + gRNA
Application:
Genome Editing with Engineered Nucleases
Gene:
Complement Component 3 (C3)
Gene ID:
718 (Human, C3)
Synonyms:
C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
Vector type:
Lentiviral Vector
Vector backbone:
pCLIP-dual-SFFV-ZsGreen
Resistance Gene:
Ampicillin, Zeocin
Selection Marker:
Puromycin
Promoter:
SFFV Promoter, U6 Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Viral particles:
ABIN5061631

Components:
- Two vectors containing two gRNAs in each vector
- Negative control
- Available as bacterial glycerol stocks or viral particles
- Cas9 expression vectors can be purchased separately
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN5042686
$503.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Application:
RNA Interference
Gene:
Complement Component 3
Gene ID:
718 (Human, C3)
Synonyms:
AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, AI255234, HSE-MSF, Plp, C3, C3-1, sb:cb26, si:dkey-76b14.4, wu:fi34b03, wu:fj86e11, C3d, asp, cpamd1, c3
Purification:
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Components:
This product is provided as two 5 nmol vials (10 nmol), three 5 nmol vials (15 nmol) or 2x three 5 nmol vials (30 nmol) of lyophilized siRNA oligo duplexes. Each vial contains slightly different sequences to ensure full knockout of the gene. Each vial contains slightly different sequences to ensure full knockout of the gene. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. The siRNA oligos are also chemically modified (2'-OMe) for increased stability and enhanced knockdown in vitro and in vivo.
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5782341
$516.85
Plus shipping costs $45.00
Delivery in 16 to 26 Business Days

Application:
RNA Interference
Gene:
Complement Component 3
Gene ID:
24232 (Rat (Rattus), C3)
Synonyms:
AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, AI255234, HSE-MSF, Plp, C3, C3-1, sb:cb26, si:dkey-76b14.4, wu:fi34b03, wu:fj86e11, C3d, asp, cpamd1, c3
Purification:
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Components:
This product is provided as two 5 nmol vials (10 nmol), three 5 nmol vials (15 nmol) or 2x three 5 nmol vials (30 nmol) of lyophilized siRNA oligo duplexes. Each vial contains slightly different sequences to ensure full knockout of the gene. Each vial contains slightly different sequences to ensure full knockout of the gene. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. The siRNA oligos are also chemically modified (2'-OMe) for increased stability and enhanced knockdown in vitro and in vivo.
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5782342
$516.85
Plus shipping costs $45.00
Delivery in 16 to 26 Business Days
  • <
  • 1

Synonyms and alternative names related to C3

  • complement C3 (C3)
  • complement component 3 (C3)
  • complement component c3a, duplicate 1 (c3a.1)
  • complement component 3 L homeolog (c3.L)
  • complement C3 (LOC443475)
  • complement component 3 (c3)
  • complement component C3 (c3-1)
  • complement C3-like (LOC100060539)
  • AHUS5
  • AI255234
  • ARMD9
  • ASP
  • asp
  • C3
  • c3
  • C3-1
  • C3a
  • C3b
  • C3d
  • CPAMD1
  • cpamd1
  • HSE-MSF
  • Plp
  • sb:cb26
  • si:dkey-76b14.4
  • wu:fi34b03
  • wu:fj86e11

Gene-IDs for different species

GENE IDSPECIES
718 Homo sapiens
12266 Mus musculus
24232 Rattus norvegicus
280677 Bos taurus
321046 Danio rerio
396370 Gallus gallus
397072 Sus scrofa
398666 Xenopus laevis
443475 Ovis aries
455644 Pan troglodytes
476728 Canis lupus familiaris
703613 Macaca mulatta
100009121 Oryctolagus cuniculus
100135462 Cavia porcellus
100216255 Xenopus (Silurana) tropicalis
100136951 Oncorhynchus mykiss
100060539 Equus caballus

Protein level used designations for C3

  • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
  • C3a anaphylatoxin
  • acylation-stimulating protein cleavage product
  • complement C3
  • complement component C3
  • complement component C3a
  • complement component C3b
  • prepro-C3
  • acylation stimulating protein
  • complement component 3d
  • complement factor 3
  • cb26
  • complement component 3
  • complement C3 alpha chain
  • complement component C3d
Other products related to C3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com