Caspase 8 (Caspase 8, CASP8)
Short Description: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined. [provided by RefSeq, Jul 2008].
More information related to gene Caspase 8.
More information related to gene Caspase 8.
Products related to Caspase 8 Gene:
Recommended next Filters:
86 results
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)
- NCBI Accession:
- NM_022277
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5251400
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)
- NCBI Accession:
- NM_009812
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5251399
$857.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)
- NCBI Accession:
- NM_009812
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5251398
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)
- NCBI Accession:
- NM_001080124
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5251397
$857.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)
- NCBI Accession:
- NM_001080124
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5251396
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)
- NCBI Accession:
- NM_022277
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5251401
$857.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)
- NCBI Accession:
- NM_001080126
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Catalog No. ABIN5749451
$813.75
Plus shipping costs $50.00
1 μg
Shipping to:
United States
Delivery in 11 to 22 Business Days
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)
- NCBI Accession:
- NM_022277
- Species:
- Rat
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Catalog No. ABIN5749452
$813.75
Plus shipping costs $50.00
1 μg
Shipping to:
United States
Delivery in 11 to 22 Business Days
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)
- NCBI Accession:
- NM_009812
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Catalog No. ABIN5749450
$813.75
Plus shipping costs $50.00
1 μg
Shipping to:
United States
Delivery in 11 to 22 Business Days
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)
- NCBI Accession:
- NM_001228
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Catalog No. ABIN5749449
$181.35
Plus shipping costs $50.00
1 μg
Shipping to:
United States
Delivery in 11 to 22 Business Days
Synonyms and alternative names related to Caspase 8
- caspase 8 L homeolog (casp8.L)
- death related ced-3/Nedd2-like protein (LOC661095)
- caspase 8 (CASP8)
- caspase-8 (LOC5563818)
- caspase-8 (casp8)
- caspase-8-like (LOC100222284)
- caspase 8 (Casp8)
- caspase 8, apoptosis-related cysteine peptidase (casp8)
- ALPS2B
- CAP4
- CASP-8
- Casp-8
- casp8
- CASP8
- casp8-A
- caspase-8
- FLICE
- MACH
- Mch5
- MCH5
- xCaspase-8
- zgc:92075
Gene-IDs for different species
Protein level used designations for Caspase 8
- caspase-8
- xcaspase 8
- death related ced-3/Nedd2-like protein
- GLEAN_14026
- caspase 8, apoptosis-related cysteine peptidase
- caspase 8
- caspase-8-like
- DEATH effector domain caspase
- Fas-linked ICE-like protease
- FADD-homologous ICE/CED-3-like protease
- FADD-like ICE
- ICE-like apoptotic protease 5
- MACH-alpha-1/2/3 protein
- MACH-beta-1/2/3/4 protein
- MORT1-associated ced-3 homolog
- apoptotic cysteine protease
- apoptotic protease Mch-5
- caspase 8, apoptosis-related cysteine protease
- caspase-8a
- cysteine protease
Proteomics products related to Caspase 8 Gene
Other products related to Caspase 8 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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