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CPSF4 (Cleavage and Polyadenylation Specific Factor 4, 30kDa, CPSF4)

Short Description: Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
More information related to gene CPSF4.

Products related to CPSF4 Gene:

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72 results

Human CPSF4 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5739139
Catalog No. ABIN5739139
Type:
ORF
Application:
Cloning
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Synonyms:
CPSF4, Cpsf4, LOC733099, LOC100360200, cpsf4.S, cpsf4
Insert length:
732 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human CPSF4 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5739138
Catalog No. ABIN5739138
Type:
ORF
Application:
Cloning
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Synonyms:
CPSF4, Cpsf4, LOC733099, LOC100360200, cpsf4.S, cpsf4
Insert length:
735 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human CPSF4 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4474257
Catalog No. ABIN4474257
Type:
cDNA
Application:
Protein Expression
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Synonyms:
CPSF4, Cpsf4, LOC733099, LOC100360200, cpsf4.S, cpsf4
Insert length:
735 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CPSF4 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4474256
Catalog No. ABIN4474256
Type:
cDNA
Application:
Protein Expression
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Synonyms:
CPSF4, Cpsf4, LOC733099, LOC100360200, cpsf4.S, cpsf4
Insert length:
735 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat CPSF4 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
NCBI Accession:
NM_001012351
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5116246
Catalog No. ABIN5116246
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
NCBI Accession:
NM_001012351
Species:
Rat
Synonyms:
CPSF4, Cpsf4, LOC733099, LOC100360200, cpsf4.S, cpsf4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cpsf4
Format:
Viral Particles
Storage:
-80 °C
Mouse CPSF4 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
NCBI Accession:
NM_178576
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5116244
Catalog No. ABIN5116244
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
NCBI Accession:
NM_178576
Species:
Mouse
Synonyms:
CPSF4, Cpsf4, LOC733099, LOC100360200, cpsf4.S, cpsf4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cpsf4
Format:
Viral Particles
Storage:
-80 °C
Human CPSF4 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
NCBI Accession:
NM_006693
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5116242
Catalog No. ABIN5116242
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
NCBI Accession:
NM_006693
Species:
Human
Synonyms:
CPSF4, Cpsf4, LOC733099, LOC100360200, cpsf4.S, cpsf4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CPSF4
Format:
Viral Particles
Storage:
-80 °C
Human CPSF4 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4760631
Catalog No. ABIN4760631
Type:
cDNA
Application:
Cloning
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Synonyms:
CPSF4, Cpsf4, LOC733099, LOC100360200, cpsf4.S, cpsf4
Insert length:
735 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CPSF4 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4760632
Catalog No. ABIN4760632
Type:
cDNA
Application:
Cloning
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Synonyms:
CPSF4, Cpsf4, LOC733099, LOC100360200, cpsf4.S, cpsf4
Insert length:
735 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CPSF4 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4829481
Catalog No. ABIN4829481
Type:
cDNA
Application:
Cloning
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Synonyms:
CPSF4, Cpsf4, LOC733099, LOC100360200, cpsf4.S, cpsf4
Insert length:
732 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC
    • pCMV6-XL5
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to CPSF4

  • cleavage and polyadenylation specific factor 4 (CPSF4)
  • cleavage and polyadenylation specific factor 4, 30kDa (Cpsf4)
  • cleavage and polyadenylation specific factor 4 (LOC733099)
  • cleavage and polyadenylation specific factor 4 (LOC100360200)
  • cleavage and polyadenylation specific factor 4 S homeolog (cpsf4.S)
  • cleavage and polyadenylation specific factor 4 (cpsf4)
  • cleavage and polyadenylation specific factor 4 (Cpsf4)
  • 30kDa
  • C79664
  • cpsf30
  • CPSF30
  • nar
  • NAR
  • neb1
  • NEB1

Gene-IDs for different species

Protein level used designations for CPSF4

  • no arches
  • GLEAN_10339
  • cleavage and polyadenylation specific factor 4
  • cleavage and polyadenylation specificity factor subunit 4
  • cleavage and polyadenylation specific factor 4, 30kDa
  • CPSF 30 kDa subunit
  • cleavage and polyadenylation specific factor 4, 30kD subunit
  • cleavage and polyadenylation specificity factor 30 kDa subunit
  • clipper homolog
  • clipper/CPSF 30K
  • musculus clipper/cleavage and polyadenylation specificity factor 30 kDa subunit
  • NS1 effector domain-binding protein 1
  • cleavage-polyadenylation specificity factor, 30kD
  • neb-1
  • no arches homolog
  • no arches-like zinc finger protein
  • cleavage-polyadenylation specificity factor, 30 kD
Other products related to CPSF4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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