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FBXW7 (F-Box and WD Repeat Domain Containing 7, FBXW7)

Short Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class\; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012].
More information related to gene FBXW7.

Products related to FBXW7 Gene:

67 results :

Human FBXW7 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5750052
Datasheet
Catalog No. ABIN5750052
Type:
ORF
Application:
Cloning
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
Species:
Human
Synonyms:
Fbxw7, FBXW7, fbxw7
Insert length:
2124 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human FBXW7 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4484590
Datasheet
Catalog No. ABIN4484590
Type:
cDNA
Application:
Protein Expression
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
Species:
Human
Synonyms:
Fbxw7, FBXW7, fbxw7
Insert length:
2124 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse FBXW7 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
NCBI Accession:
NM_001177773
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4443521
Datasheet
Catalog No. ABIN4443521
Type:
cDNA
Application:
Protein Expression
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
NCBI Accession:
NM_001177773
Species:
Mouse
Synonyms:
Fbxw7, FBXW7, fbxw7
Insert length:
2133 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse FBXW7 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
NCBI Accession:
NM_001177773
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5252559
Datasheet
Catalog No. ABIN5252559
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
NCBI Accession:
NM_001177773
Species:
Mouse
Synonyms:
Fbxw7, FBXW7, fbxw7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fbxw7
Format:
Viral Particles
Storage:
-80 °C
Human FBXW7 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
NCBI Accession:
NM_018315
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5252557
Datasheet
Catalog No. ABIN5252557
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
NCBI Accession:
NM_018315
Species:
Human
Synonyms:
Fbxw7, FBXW7, fbxw7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of FBXW7
Format:
Viral Particles
Storage:
-80 °C
Mouse FBXW7 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
NCBI Accession:
NM_001177773
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5137090
Datasheet
Catalog No. ABIN5137090
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
NCBI Accession:
NM_001177773
Species:
Mouse
Synonyms:
Fbxw7, FBXW7, fbxw7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fbxw7
Format:
Viral Particles
Storage:
-80 °C
Human FBXW7 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
NCBI Accession:
NM_018315
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5137088
Datasheet
Catalog No. ABIN5137088
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
NCBI Accession:
NM_018315
Species:
Human
Synonyms:
Fbxw7, FBXW7, fbxw7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of FBXW7
Format:
Viral Particles
Storage:
-80 °C
Human FBXW7 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4831481
Datasheet
Catalog No. ABIN4831481
Type:
cDNA
Application:
Cloning
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
Species:
Human
Synonyms:
Fbxw7, FBXW7, fbxw7
Insert length:
2124 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human FBXW7 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4628061
Datasheet
Catalog No. ABIN4628061
Type:
cDNA
Application:
Cloning
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
Species:
Human
Synonyms:
Fbxw7, FBXW7, fbxw7
Insert length:
2124 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse FBXW7 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
NCBI Accession:
NM_001177773
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4642838
Datasheet
Catalog No. ABIN4642838
Type:
cDNA
Application:
Cloning
Gene:
F-Box and WD Repeat Domain Containing 7 (FBXW7)
NCBI Accession:
NM_001177773
Species:
Mouse
Synonyms:
Fbxw7, FBXW7, fbxw7
Insert length:
2133 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pcDNA3.1+C-(K)-DYK
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-XL5
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to FBXW7

  • F-box and WD repeat domain containing 7 (Fbxw7)
  • F-box and WD repeat domain containing 7 (FBXW7)
  • F-box and WD repeat domain containing 7 (fbxw7)
  • F-box and WD-40 domain protein 7 (Fbxw7)
  • 1110001A17Rik
  • AGO
  • cdc4
  • CDC4
  • Cdc4
  • FBW6
  • FBW7
  • Fbw7
  • Fbwd6
  • FBX30
  • Fbx30
  • FBXO30
  • Fbxo30
  • FBXW6
  • Fbxw6
  • hAgo
  • hCdc4
  • SEL-10
  • SEL10

Gene-IDs for different species

Protein level used designations for FBXW7

  • F-box and WD-40 domain protein 7
  • F-box/WD repeat-containing protein 7
  • F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)
  • F-box protein FBW7
  • F-box protein FBX30
  • F-box protein SEL-10
  • archipelago
  • homolog of C elegans sel-10
  • F-box and WD-40 domain protein 7, archipelago homolog
  • F-box and WD-40 domain-containing protein 7
  • F-box protein Fbxw6
  • F-box-WD40 repeat protein 6
  • f-box only protein 30
Other products related to FBXW7 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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