Fibrillin 1 (Fibrillin 1, FBN1)

Short Description: This gene encodes a member of the fibrillin family. The encoded protein is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome. [provided by RefSeq, Jul 2008].
More information related to gene Fibrillin 1.
Products related to Fibrillin 1 Gene:
74 Products
Type
  • 70
  • 4
Species
  • 30
  • 22
  • 22
Application
  • 30
  • 23
  • 17
  • 16
Fusion tag
  • 27
  • 9
  • 8
  • 8
  • 4
Vector Backbone
  • 6
  • 6
  • 6
  • 4
  • 3
Vector
  • 23
  • 21
  • 12
  • 9
  • 5
Insert
  • 29
  • 19
  • 8
  • 6
  • 6
Oligo-Type
  • 4
Resistance Gene
  • 34
  • 27
  • 6
  • 3
  • 2
Expression Type
  • 68
  • 47
Selectable Marker
  • 26
  • 23
  • 2
Promoter
  • 29
  • 16
  • 13
  • 8
  • 6
Format
  • 27
  • 25
  • 16
  • 6

Type:
cDNA
Application:
Cloning
Gene:
Fibrillin 1 (FBN1)
Gene ID:
2200 (Human, FBN1)
Synonyms:
FBN1, Fbn1
Vector type:
Cloning Vector
Vector backbone:
pCR-XL-TOPO
Resistance Gene:
Kanamycin
Selection Marker:
Bleomycin

Sequencing Primer:
  • T7
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3996187
$118.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Cloning
Gene:
Fibrillin 1 (FBN1)
Gene ID:
2200 (Human, FBN1)
Synonyms:
FBN1, Fbn1
Vector type:
Cloning Vector
Vector backbone:
pCR-XL-TOPO
Resistance Gene:
Kanamycin
Selection Marker:
Bleomycin

Sequencing Primer:
  • T7
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3996188
$162.44
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Cloning
Gene:
Fibrillin 1 (FBN1)
Species:
Human
Synonyms:
FBN1, Fbn1
Insert length:
8616 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient

Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4702277
$300.00
500 ng
Plus shipping costs $45.00
Delivery in 11 to 21 Business Days

Type:
cDNA
Application:
Cloning
Gene:
Fibrillin 1 (FBN1)
Species:
Human
Synonyms:
FBN1, Fbn1
Insert length:
8616 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient

Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4831407
$300.00
500 ng
Plus shipping costs $45.00
Delivery in 11 to 21 Business Days

Application:
RNA Interference
Gene:
Fibrillin 1
Species:
Mouse (Murine)
Synonyms:
FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2, AI536462, B430209H23, Fib-1, Tsk
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • Fbn1 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3350436
$420.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Application:
RNA Interference
Gene:
Fibrillin 1
Species:
Human
Synonyms:
FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2, AI536462, B430209H23, Fib-1, Tsk
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • FBN1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3341325
$420.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Application:
RNA Interference
Gene:
Fibrillin 1
Species:
Rat (Rattus)
Synonyms:
FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2, AI536462, B430209H23, Fib-1, Tsk
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • Fbn1 (Rat) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3352498
$420.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Fibrillin 1 (FBN1)
NCBI Accession:
NM_000138
Species:
Human
Synonyms:
FBN1, Fbn1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of FBN1
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5088936
$420.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Fibrillin 1 (FBN1)
NCBI Accession:
NM_031825
Species:
Rat (Rattus)
Synonyms:
FBN1, Fbn1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fbn1
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5088940
$420.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Fibrillin 1 (FBN1)
NCBI Accession:
NM_007993
Species:
Mouse (Murine)
Synonyms:
FBN1, Fbn1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fbn1
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5088938
$420.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available

Type:
gRNA + gRNA
Application:
Genome Editing with Engineered Nucleases
Gene:
Fibrillin 1 (FBN1)
Gene ID:
2200 (Human, FBN1)
Synonyms:
FBN1, Fbn1
Vector type:
Lentiviral Vector
Vector backbone:
pCLIP-dual-SFFV-ZsGreen
Resistance Gene:
Ampicillin, Zeocin
Selection Marker:
Puromycin
Promoter:
SFFV Promoter, U6 Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Viral particles:
ABIN5051300

Components:
- Two vectors containing two gRNAs in each vector
- Negative control
- Available as bacterial glycerol stocks or viral particles
- Cas9 expression vectors can be purchased separately
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN5032355
$503.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Application:
RNA Interference
Gene:
Fibrillin 1
Gene ID:
2200 (Human, FBN1)
Synonyms:
FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2, AI536462, B430209H23, Fib-1, Tsk
Purification:
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Components:
This product is provided as two 5 nmol vials (10 nmol), three 5 nmol vials (15 nmol) or 2x three 5 nmol vials (30 nmol) of lyophilized siRNA oligo duplexes. Each vial contains slightly different sequences to ensure full knockout of the gene. Each vial contains slightly different sequences to ensure full knockout of the gene. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. The siRNA oligos are also chemically modified (2'-OMe) for increased stability and enhanced knockdown in vitro and in vivo.
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5783984
$516.85
Plus shipping costs $45.00
Delivery in 16 to 26 Business Days

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Fibrillin 1 (FBN1)
NCBI Accession:
NM_000138
Species:
Human
Synonyms:
FBN1, Fbn1
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of FBN1
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5204092
$520.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Fibrillin 1 (FBN1)
NCBI Accession:
NM_007993
Species:
Mouse (Murine)
Synonyms:
FBN1, Fbn1
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fbn1
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5204094
$520.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Fibrillin 1 (FBN1)
NCBI Accession:
NM_031825
Species:
Rat (Rattus)
Synonyms:
FBN1, Fbn1
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fbn1
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5204096
$520.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available

Type:
shRNA
Application:
RNA Interference
Gene:
Fibrillin 1 (FBN1)
Gene ID:
14118 (Mouse (Murine), FBN1)
Synonyms:
FBN1, Fbn1
Vector type:
Lentiviral Vector
Vector backbone:
pZIP-mCMV-ZsGreen
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
mCMV Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Empty vector controls:
ABIN5691888
Viral particles:
ABIN3779641

Components:
3 separate shRNA clones and a non-targeting control
Format:
Glycerol Stock
Buffer:
E. coli bacterial culture in LB-Lennox (low salt) broth with 8 % glycerol.
Storage:
-80 °C
Catalog No. ABIN3779640
$703.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
Fibrillin 1 (FBN1)
Gene ID:
83727 (Rat (Rattus), FBN1)
Synonyms:
FBN1, Fbn1
Vector type:
Lentiviral Vector
Vector backbone:
pZIP-mCMV-ZsGreen
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
mCMV Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Empty vector controls:
ABIN5691888
Viral particles:
ABIN3779641

Components:
3 separate shRNA clones and a non-targeting control
Format:
Glycerol Stock
Buffer:
E. coli bacterial culture in LB-Lennox (low salt) broth with 8 % glycerol.
Storage:
-80 °C
Catalog No. ABIN4140518
$703.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
Fibrillin 1 (FBN1)
Gene ID:
2200 (Human, FBN1)
Synonyms:
FBN1, Fbn1
Vector type:
Lentiviral Vector
Vector backbone:
pZIP-mCMV-ZsGreen
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
mCMV Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Empty vector controls:
ABIN5691888
Viral particles:
ABIN3779641

Components:
3 separate shRNA clones and a non-targeting control
Format:
Glycerol Stock
Buffer:
E. coli bacterial culture in LB-Lennox (low salt) broth with 8 % glycerol.
Storage:
-80 °C
Catalog No. ABIN3478578
$703.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
Fibrillin 1 (FBN1)
Species:
Human
Synonyms:
FBN1, Fbn1
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable

Empty vector controls:
ABIN4948187

Components:
  • Gene-specific shRNA in pGFPC-shLenti vector, 4 unique constructs per gene, 5 ug per vial.
  • HuSH 29-mer Scrambled in pGFP-C-shLenti 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3737892
$715.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
Fibrillin 1 (FBN1)
Species:
Human
Synonyms:
FBN1, Fbn1
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable

Empty vector controls:
ABIN4948189

Components:
  • Gene-specific shRNA expression pRS vectors, 5 ug plasmid DNA per vial.
  • Four unique constructs per gene.
  • HuSH 29-mer NonEffective Scrambled pRS 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3654990
$715.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days
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  • 1

Synonyms and alternative names related to Fibrillin 1

  • fibrillin 1 (FBN1)
  • fibrillin 1 (Fbn1)
  • ACMICD
  • AI536462
  • B430209H23
  • ECTOL1
  • FBN
  • FBN1
  • Fib-1
  • GPHYSD2
  • MASS
  • MFS1
  • OCTD
  • SGS
  • SSKS
  • Tsk
  • WMS
  • WMS2

Gene-IDs for different species

GENE IDSPECIES
453411 Pan troglodytes
100055741 Equus caballus
281154 Bos taurus
2200 Homo sapiens
478293 Canis lupus familiaris
414836 Sus scrofa
14118 Mus musculus
83727 Rattus norvegicus
100717565 Cavia porcellus
373992 Gallus gallus
101109620 Ovis aries
100350931 Oryctolagus cuniculus

Protein level used designations for Fibrillin 1

  • fibrillin 1
  • MP340
  • fibrillin-1
  • fibrillin 15
  • fibrillin 1 (Marfan syndrome)
  • tight skin
Other products related to Fibrillin 1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com