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HMBS (Hydroxymethylbilane Synthase, HMBS)

Short Description: This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
More information related to gene HMBS.

Products related to HMBS Gene:

73 results :

Human HMBS ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Hydroxymethylbilane Synthase (HMBS)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5724850
Datasheet
Catalog No. ABIN5724850
Type:
ORF
Application:
Cloning
Gene:
Hydroxymethylbilane Synthase (HMBS)
Species:
Human
Synonyms:
HMBS, Hmbs, hmbs, hmbs.2.S, hmbs.L, CNC02250, hem3, hemC, Trad_0335, Plabr_2100, Sgly_3113, SMLT_RS19660, PMI_RS16580, hmbsa, hmbsb
Insert length:
1086 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human HMBS cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Hydroxymethylbilane Synthase (HMBS)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4476594
Datasheet
Catalog No. ABIN4476594
Type:
cDNA
Application:
Protein Expression
Gene:
Hydroxymethylbilane Synthase (HMBS)
Species:
Human
Synonyms:
HMBS, Hmbs, hmbs, hmbs.2.S, hmbs.L, CNC02250, hem3, hemC, Trad_0335, Plabr_2100, Sgly_3113, SMLT_RS19660, PMI_RS16580, hmbsa, hmbsb
Insert length:
1086 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat HMBS CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Hydroxymethylbilane Synthase (HMBS)
NCBI Accession:
NM_013168
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5090210
Datasheet
Catalog No. ABIN5090210
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Hydroxymethylbilane Synthase (HMBS)
NCBI Accession:
NM_013168
Species:
Rat
Synonyms:
HMBS, Hmbs, hmbs, hmbs.2.S, hmbs.L, CNC02250, hem3, hemC, Trad_0335, Plabr_2100, Sgly_3113, SMLT_RS19660, PMI_RS16580, hmbsa, hmbsb
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Hmbs
Format:
Viral Particles
Storage:
-80 °C
Mouse HMBS CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Hydroxymethylbilane Synthase (HMBS)
NCBI Accession:
NM_013551
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5090208
Datasheet
Catalog No. ABIN5090208
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Hydroxymethylbilane Synthase (HMBS)
NCBI Accession:
NM_013551
Species:
Mouse
Synonyms:
HMBS, Hmbs, hmbs, hmbs.2.S, hmbs.L, CNC02250, hem3, hemC, Trad_0335, Plabr_2100, Sgly_3113, SMLT_RS19660, PMI_RS16580, hmbsa, hmbsb
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Hmbs
Format:
Viral Particles
Storage:
-80 °C
Human HMBS CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Hydroxymethylbilane Synthase (HMBS)
NCBI Accession:
NM_000190
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5090206
Datasheet
Catalog No. ABIN5090206
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Hydroxymethylbilane Synthase (HMBS)
NCBI Accession:
NM_000190
Species:
Human
Synonyms:
HMBS, Hmbs, hmbs, hmbs.2.S, hmbs.L, CNC02250, hem3, hemC, Trad_0335, Plabr_2100, Sgly_3113, SMLT_RS19660, PMI_RS16580, hmbsa, hmbsb
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of HMBS
Format:
Viral Particles
Storage:
-80 °C
Human HMBS cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Hydroxymethylbilane Synthase (HMBS)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4832984
Datasheet
Catalog No. ABIN4832984
Type:
cDNA
Application:
Cloning
Gene:
Hydroxymethylbilane Synthase (HMBS)
Species:
Human
Synonyms:
HMBS, Hmbs, hmbs, hmbs.2.S, hmbs.L, CNC02250, hem3, hemC, Trad_0335, Plabr_2100, Sgly_3113, SMLT_RS19660, PMI_RS16580, hmbsa, hmbsb
Insert length:
1086 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HMBS cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Hydroxymethylbilane Synthase (HMBS)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4762969
Datasheet
Catalog No. ABIN4762969
Type:
cDNA
Application:
Cloning
Gene:
Hydroxymethylbilane Synthase (HMBS)
Species:
Human
Synonyms:
HMBS, Hmbs, hmbs, hmbs.2.S, hmbs.L, CNC02250, hem3, hemC, Trad_0335, Plabr_2100, Sgly_3113, SMLT_RS19660, PMI_RS16580, hmbsa, hmbsb
Insert length:
1086 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HMBS cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Hydroxymethylbilane Synthase (HMBS)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4703854
Datasheet
Catalog No. ABIN4703854
Type:
cDNA
Application:
Cloning
Gene:
Hydroxymethylbilane Synthase (HMBS)
Species:
Human
Synonyms:
HMBS, Hmbs, hmbs, hmbs.2.S, hmbs.L, CNC02250, hem3, hemC, Trad_0335, Plabr_2100, Sgly_3113, SMLT_RS19660, PMI_RS16580, hmbsa, hmbsb
Insert length:
1086 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HMBS cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Hydroxymethylbilane Synthase (HMBS)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4437689
Datasheet
Catalog No. ABIN4437689
Type:
cDNA
Application:
Protein Expression
Gene:
Hydroxymethylbilane Synthase (HMBS)
Species:
Human
Synonyms:
HMBS, Hmbs, hmbs, hmbs.2.S, hmbs.L, CNC02250, hem3, hemC, Trad_0335, Plabr_2100, Sgly_3113, SMLT_RS19660, PMI_RS16580, hmbsa, hmbsb
Insert length:
1086 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse HMBS ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Hydroxymethylbilane Synthase (HMBS)
NCBI Accession:
NM_013551
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5724851
Datasheet
Catalog No. ABIN5724851
Type:
ORF
Application:
Cloning
Gene:
Hydroxymethylbilane Synthase (HMBS)
NCBI Accession:
NM_013551
Species:
Mouse
Synonyms:
HMBS, Hmbs, hmbs, hmbs.2.S, hmbs.L, CNC02250, hem3, hemC, Trad_0335, Plabr_2100, Sgly_3113, SMLT_RS19660, PMI_RS16580, hmbsa, hmbsb
Insert length:
1086 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pcDNA3.1+C-(K)-DYK
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-XL4
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to HMBS

  • hydroxymethylbilane synthase (HMBS)
  • hydroxymethylbilane synthase (Hmbs)
  • hydroxymethylbilane synthase (hmbs)
  • hydroxymethylbilane synthase S homeolog (hmbs.2.S)
  • hydroxymethylbilane synthase L homeolog (hmbs.L)
  • hydroxymethylbilane synthase (CNC02250)
  • hydroxymethylbilane synthase (predicted) (hem3)
  • hydroxymethylbilane synthase (hemC)
  • Hydroxymethylbilane synthase (Trad_0335)
  • hydroxymethylbilane synthase (Plabr_2100)
  • hydroxymethylbilane synthase (Sgly_3113)
  • hydroxymethylbilane synthase (SMLT_RS19660)
  • hydroxymethylbilane synthase (PMI_RS16580)
  • hydroxymethylbilane synthase a (hmbsa)
  • hydroxymethylbilane synthase, b (hmbsb)
  • DDBDRAFT_0186148
  • DDBDRAFT_0231417
  • DDB_0186148
  • DDB_0231417
  • hemC
  • Hmbs
  • hmbs
  • hmbsl
  • id:ibd5004
  • im:7140060
  • NV50236
  • PBG-D
  • pbg-d
  • PBGD
  • pbgd
  • PORC
  • SPAC806.01
  • T25658
  • UPS
  • ups
  • Ups
  • URO-S
  • Uros1
  • zgc:64128
  • zgc:110690

Gene-IDs for different species

Protein level used designations for HMBS

  • porphobilinogen deaminase
  • porphyria, acute; Chester type
  • pre-uroporphyrinogen synthase
  • uroporphyrinogen I synthase
  • uroporphyrinogen I synthetase
  • alternative name: porphobilinogen deaminase
  • hydroxymethylbilane synthase
  • Hydroxymethylbilane synthase
  • PBG-D
  • porphobilinogen deaminase-like
  • hydroxymethylbilane synthase, b
Other products related to HMBS such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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