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KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1, KCNQ1)

Short Description: This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011].
More information related to gene KCNQ1.

Products related to KCNQ1 Gene:

65 results :

Human KCNQ1 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA PExp Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN5772714
Datasheet
Catalog No. ABIN5772714
Type:
cDNA
Application:
Protein Expression
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
Species:
Human
Synonyms:
KCNQ1, KCNQ, kcnq1, Kcnq1, kcnq1.L
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human KCNQ1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA PExp Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN5772713
Datasheet
Catalog No. ABIN5772713
Type:
cDNA
Application:
Protein Expression
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
Species:
Human
Synonyms:
KCNQ1, KCNQ, kcnq1, Kcnq1, kcnq1.L
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human KCNQ1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5741298
Datasheet
Catalog No. ABIN5741298
Type:
ORF
Application:
Cloning
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
Species:
Human
Synonyms:
KCNQ1, KCNQ, kcnq1, Kcnq1, kcnq1.L
Insert length:
1650 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human KCNQ1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4484994
Datasheet
Catalog No. ABIN4484994
Type:
cDNA
Application:
Protein Expression
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
Species:
Human
Synonyms:
KCNQ1, KCNQ, kcnq1, Kcnq1, kcnq1.L
Insert length:
1650 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse KCNQ1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
NCBI Accession:
NM_008434
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235652
Datasheet
Catalog No. ABIN5235652
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
NCBI Accession:
NM_008434
Species:
Mouse
Synonyms:
KCNQ1, KCNQ, kcnq1, Kcnq1, kcnq1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Kcnq1
Format:
Viral Particles
Storage:
-80 °C
Human KCNQ1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
NCBI Accession:
NM_181798
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235650
Datasheet
Catalog No. ABIN5235650
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
NCBI Accession:
NM_181798
Species:
Human
Synonyms:
KCNQ1, KCNQ, kcnq1, Kcnq1, kcnq1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of KCNQ1
Format:
Viral Particles
Storage:
-80 °C
Rat KCNQ1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
NCBI Accession:
NM_032073
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235654
Datasheet
Catalog No. ABIN5235654
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
NCBI Accession:
NM_032073
Species:
Rat
Synonyms:
KCNQ1, KCNQ, kcnq1, Kcnq1, kcnq1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Kcnq1
Format:
Viral Particles
Storage:
-80 °C
Rat KCNQ1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
NCBI Accession:
NM_032073
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120290
Datasheet
Catalog No. ABIN5120290
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
NCBI Accession:
NM_032073
Species:
Rat
Synonyms:
KCNQ1, KCNQ, kcnq1, Kcnq1, kcnq1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Kcnq1
Format:
Viral Particles
Storage:
-80 °C
Mouse KCNQ1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
NCBI Accession:
NM_008434
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120288
Datasheet
Catalog No. ABIN5120288
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
NCBI Accession:
NM_008434
Species:
Mouse
Synonyms:
KCNQ1, KCNQ, kcnq1, Kcnq1, kcnq1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Kcnq1
Format:
Viral Particles
Storage:
-80 °C
Human KCNQ1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
NCBI Accession:
NM_181798
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120286
Datasheet
Catalog No. ABIN5120286
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)
NCBI Accession:
NM_181798
Species:
Human
Synonyms:
KCNQ1, KCNQ, kcnq1, Kcnq1, kcnq1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of KCNQ1
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • His-GST
    • His-MBP
    • HA tag
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pPB-His-GST
    • pPB-His-MBP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pCMV6-XL4
    • pDONR223
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to KCNQ1

  • potassium voltage-gated channel subfamily Q member 1 (KCNQ1)
  • KCNQ potassium channel (KCNQ)
  • potassium voltage-gated channel, KQT-like subfamily, member 1 (KCNQ1)
  • potassium channel, voltage gated KQT-like subfamily Q, member 1 (kcnq1)
  • voltage gated potassium channel subunit (kcnq1)
  • potassium voltage-gated channel subfamily Q member 1 (Kcnq1)
  • potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog (kcnq1.L)
  • potassium voltage-gated channel, KQT-like subfamily, member 1 (kcnq1)
  • potassium voltage-gated channel, subfamily Q, member 1 (Kcnq1)
  • ATFB1
  • ATFB3
  • AW559127
  • CG12215
  • CG12915
  • CG33135
  • DKCNQ
  • dKCNQ
  • Dmel\\CG33135
  • JLNS1
  • KCNA8
  • KCNA9
  • Kcna9
  • kcnq1
  • KCNQ1
  • kcnq1-A
  • kqt-3
  • Kv1.9
  • Kv7.1
  • kv7.1
  • KvLQT-1
  • KVLQT1
  • Kvlqt1
  • KvLQT1
  • LQT
  • LQT1
  • RWS
  • SQT2
  • WRS
  • xkvlqt1
  • zgc:158384

Gene-IDs for different species

Protein level used designations for KCNQ1

  • IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1
  • kidney and cardiac voltage dependend K+ channel
  • potassium voltage-gated channel subfamily KQT member 1
  • slow delayed rectifier channel subunit
  • voltage-gated potassium channel subunit Kv7.1
  • CG33135-PC
  • CG33135-PD
  • CG33135-PE
  • CG33135-PF
  • CG33135-PG
  • CG33135-PH
  • CG33135-PI
  • CG33135-PJ
  • CG33135-PK
  • KCNQ-PC
  • KCNQ-PD
  • KCNQ-PE
  • KCNQ-PF
  • KCNQ-PG
  • KCNQ-PH
  • KCNQ-PI
  • KCNQ-PJ
  • KCNQ-PK
  • KCNQ-type K[+] channel
  • Potassium voltage-gated channel subfamily KQT member 1
  • potassium channel protein (KvLQT1)
  • ventricular voltage-gated K+ channel pore-forming subunit KCNQ1
  • KvLQT1 voltage-gated delayed rectifier potassium channel
  • potassium voltage-gated channel, KQT-like subfamily, member 1
  • potassium channel protein KCNQ1
  • potassium voltage-gated channel, subfamily Q, member 1
  • voltage gated potassium channel subunit
  • KQT-like 1
  • IKs producing slow voltage-gated potassium channel subunit alpha xKvLQT1
  • Voltage-gated potassium channel subunit Kv7.1
  • potassium channel protein
Other products related to KCNQ1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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