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MAP3K4 (Mitogen-Activated Protein Kinase Kinase Kinase 4, MAP3K4)

Short Description: The central core of each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which then activates a specific MAPK. While the ERK MAPKs are activated by mitogenic stimulation, the CSBP2 and JNK MAPKs are activated by environmental stresses such as osmotic shock, UV irradiation, wound stress, and inflammatory factors. This gene encodes a MAPKKK, the MEKK4 protein, also called MTK1. This protein contains a protein kinase catalytic domain at the C terminus. The N-terminal nonkinase domain may contain a regulatory domain. Expression of MEKK4 in mammalian cells activated the CSBP2 and JNK MAPK pathways, but not the ERK pathway. In vitro kinase studies indicated that recombinant MEKK4 can specifically phosphorylate and activate PRKMK6 and SERK1, MAPKKs that activate CSBP2 and JNK, respectively but cannot phosphorylate PRKMK1, an MAPKK that activates ERKs. MEKK4 is a major mediator of environmental stresses that activate the CSBP2 MAPK pathway, and a minor mediator of the JNK pathway. Two alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
More information related to gene MAP3K4.

Products related to MAP3K4 Gene:

91 results:

Human MAP3K4 cDNA Clone in Cloning Vector Plasmid

cDNA Clon Cloning Vector pCR-XL-TOPO Kanamycin unconjugated
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
Gene ID:
4216 (Human, MAP3K4)
Vector type:
Cloning Vector
Vector backbone:
pCR-XL-TOPO
Resistance Gene:
Kanamycin
Selection Marker:
Bleomycin
Catalog No. ABIN3996288
$162.44
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

Human MAP3K4 cDNA Clone in Cloning Vector Plasmid

cDNA Clon Cloning Vector pCR-XL-TOPO Kanamycin unconjugated
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
Gene ID:
4216 (Human, MAP3K4)
Vector type:
Cloning Vector
Vector backbone:
pCR-XL-TOPO
Resistance Gene:
Kanamycin
Selection Marker:
Bleomycin
Catalog No. ABIN3996289
$162.44
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

Human MAP3K4 cDNA Clone in Cloning Vector Plasmid

cDNA Clon Cloning Vector pBluescript II SK+ Ampicillin unconjugated
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
Gene ID:
4216 (Human, MAP3K4)
Vector type:
Cloning Vector
Vector backbone:
pBluescript II SK+
Resistance Gene:
Ampicillin
Catalog No. ABIN4210112
$162.44
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

Mouse MAP3K4 cDNA Clone in Cloning Vector Plasmid

cDNA Clon Cloning Vector pYX-Asc Ampicillin T3 Promoter unconjugated
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
Gene ID:
26407 (Mouse, MAP3K4)
Vector type:
Cloning Vector
Vector backbone:
pYX-Asc
Resistance Gene:
Ampicillin
Promoter:
T3 Promoter
Catalog No. ABIN4100031
$162.44
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

Human MAP3K4 cDNA Clone in Bacterial Expression Vector (His-MBP) Plasmid

cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4705849
$300.00
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 11 to 21 Business Days

Human MAP3K4 cDNA Clone in Bacterial Expression Vector (His-GST) Plasmid

cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4834979
$300.00
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 11 to 21 Business Days

Human MAP3K4 CRISPR gRNA in Lenti Particles Plasmid

gRNA GEEN, PExp Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
NCBI Accession:
NM_005922
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120646
$420.00
Plus shipping costs $45.00 and $24.00 dry ice
local_shipping Shipping to: United States
Available

Rat MAP3K4 CRISPR gRNA in Lenti Particles Plasmid

gRNA GEEN, PExp Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
NCBI Accession:
NM_001107456
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120650
$420.00
Plus shipping costs $45.00 and $24.00 dry ice
local_shipping Shipping to: United States
Available

Mouse MAP3K4 CRISPR gRNA in Lenti Particles Plasmid

gRNA GEEN, PExp Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
NCBI Accession:
NM_011948
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120648
$420.00
Plus shipping costs $45.00 and $24.00 dry ice
local_shipping Shipping to: United States
Available

Mouse MAP3K4 siRNA Oligo Primer

RNAi MAP3K4 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3349899
$440.00
Plus shipping costs $45.00
local_shipping Shipping to: United States
Will be delivered in 16 Business Days

Human MAP3K4 siRNA Oligo Primer

RNAi MAP3K4 Species: Human HPLC purified
Application:
RNA Interference
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3342646
$440.00
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 4 to 8 Business Days

Rat MAP3K4 siRNA Oligo Primer

RNAi MAP3K4 Species: Rat HPLC purified
Application:
RNA Interference
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3357679
$440.00
Plus shipping costs $45.00
local_shipping Shipping to: United States
Will be delivered in 16 Business Days

Human MAP3K4 CRISPR gRNA + gRNA in Lentiviral Vector (ZsGreen) Plasmid

gRNA + gRNA GEEN Lentiviral Vector pCLIP-dual-SFFV-ZsGreen Ampicillin SFFV Promoter ZsGreen Transient
Type:
gRNA + gRNA
Application:
Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
Gene ID:
4216 (Human, MAP3K4)
Vector type:
Lentiviral Vector
Vector backbone:
pCLIP-dual-SFFV-ZsGreen
Resistance Gene:
Ampicillin, Zeocin
Selection Marker:
Puromycin
Promoter:
SFFV Promoter, U6 Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable
Catalog No. ABIN5037194
$503.00
Plus shipping costs $45.00
local_shipping Shipping to: United States
Will be delivered in 16 Business Days

Human MAP3K4 CRISPR gRNA + Cas9 in Lenti Particles Plasmid

gRNA + Cas9 GEEN, PExp Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
NCBI Accession:
NM_005922
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5236012
$520.00
Plus shipping costs $45.00 and $24.00 dry ice
local_shipping Shipping to: United States
Available

Mouse MAP3K4 CRISPR gRNA + Cas9 in Lenti Particles Plasmid

gRNA + Cas9 GEEN, PExp Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
NCBI Accession:
NM_011948
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5236014
$520.00
Plus shipping costs $45.00 and $24.00 dry ice
local_shipping Shipping to: United States
Available

Rat MAP3K4 CRISPR gRNA + Cas9 in Lenti Particles Plasmid

gRNA + Cas9 GEEN, PExp Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
NCBI Accession:
NM_001107456
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5236016
$520.00
Plus shipping costs $45.00 and $24.00 dry ice
local_shipping Shipping to: United States
Available

Human MAP3K4 ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag) Plasmid

ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
NCBI Accession:
NM_006724,NP_006715
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5404883
$565.00
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days

Human MAP3K4 shRNA in Lentiviral Vector (ZsGreen) Plasmid

shRNA RNAi Lentiviral Vector pZIP-mCMV-ZsGreen Ampicillin mCMV Promoter ZsGreen Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
Gene ID:
4216 (Human, MAP3K4)
Vector type:
Lentiviral Vector
Vector backbone:
pZIP-mCMV-ZsGreen
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
mCMV Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable
Catalog No. ABIN3482529
$703.00
Plus shipping costs $45.00
local_shipping Shipping to: United States
Will be delivered in 16 Business Days

Mouse MAP3K4 shRNA in Lentiviral Vector (ZsGreen) Plasmid

shRNA RNAi Lentiviral Vector pZIP-mCMV-ZsGreen Ampicillin mCMV Promoter ZsGreen Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
Gene ID:
26407 (Mouse, MAP3K4)
Vector type:
Lentiviral Vector
Vector backbone:
pZIP-mCMV-ZsGreen
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
mCMV Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable
Catalog No. ABIN3796823
$703.00
Plus shipping costs $45.00
local_shipping Shipping to: United States
Will be delivered in 16 Business Days

Rat MAP3K4 shRNA in Lentiviral Vector (ZsGreen) Plasmid

shRNA RNAi Lentiviral Vector pZIP-mCMV-ZsGreen Ampicillin mCMV Promoter ZsGreen Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4)
Gene ID:
308106 (Rat, MAP3K4)
Vector type:
Lentiviral Vector
Vector backbone:
pZIP-mCMV-ZsGreen
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
mCMV Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable
Catalog No. ABIN4182351
$703.00
Plus shipping costs $45.00
local_shipping Shipping to: United States
Will be delivered in 16 Business Days
  • Type
    • Plasmid
    • Primer
  • Species
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Fusion tag
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • ZsGreen
    • DYKDDDDK Tag,HA tag
    • DYKDDDDK Tag,His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pZIP-mCMV-ZsGreen
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-C-His
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pPM-N-D-C-HA
    • pPM-N-D-C-His
    • pRFP-C-RS
    • pRS
    • pCLIP-dual-SFFV-ZsGreen
    • pCMV6-AC-GFP
    • pCR-XL-TOPO
    • pCas-Guide
    • pBluescript II SK+
    • pCMV6-Neo
    • pYX-Asc
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
    • gRNA + gRNA
  • Oligo-Type
    • siRNA Oligo
  • Resistance Gene
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
    • Zeocin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
    • Bleomycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • SFFV Promoter
    • PGK Promoter
    • mCMV Promoter
    • T3 Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles
    • Glycerol Stock

Synonyms and alternative names related to MAP3K4

  • mitogen activated protein kinase kinase kinase 4 (Map3k4)
  • mitogen-activated protein kinase kinase kinase 4 (MAP3K4)
  • mitogen-activated protein kinase kinase kinase 4 (Map3k4)
  • D17Rp17
  • D17Rp17e
  • MAPKKK4
  • Mek4b
  • MEKK4
  • MEKK 4
  • Mekk4
  • mKIAA0213
  • MTK1
  • PRO0412
  • RP17
  • Rp17a
  • Tas

Gene-IDs for different species

GENE ID SPECIES
308106 Rattus norvegicus
4216 Homo sapiens
26407 Mus musculus

Protein level used designations for MAP3K4

  • mitogen-activated protein kinase kinase kinase 4
  • MAP three kinase 1
  • MAP/ERK kinase kinase 4
  • MAPK/ERK kinase kinase 4
  • MEK kinase 4
  • MEKK 4
  • SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of
  • dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4)
  • predicted protein of HQ0412
  • T-associated sex reversal
  • mitogen activated protein kinase kinase kinase 4
Other products related to MAP3K4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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