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MCL-1 (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1, MCL1)

Short Description: This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010].
More information related to gene MCL-1.

Products related to MCL-1 Gene:

66 results :

Human MCL1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5725476
Datasheet
Catalog No. ABIN5725476
Type:
ORF
Application:
Cloning
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
Species:
Human
Synonyms:
MCL1, Mcl1, mcl1a, mcl1b, SNORA63
Insert length:
1053 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human MCL1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4477917
Datasheet
Catalog No. ABIN4477917
Type:
cDNA
Application:
Protein Expression
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
Species:
Human
Synonyms:
MCL1, Mcl1, mcl1a, mcl1b, SNORA63
Insert length:
1053 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MCL1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
NCBI Accession:
NM_182763
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5091018
Datasheet
Catalog No. ABIN5091018
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
NCBI Accession:
NM_182763
Species:
Human
Synonyms:
MCL1, Mcl1, mcl1a, mcl1b, SNORA63
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MCL1
Format:
Viral Particles
Storage:
-80 °C
Rat MCL1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
NCBI Accession:
NM_012933
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5091022
Datasheet
Catalog No. ABIN5091022
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
NCBI Accession:
NM_012933
Species:
Rat
Synonyms:
MCL1, Mcl1, mcl1a, mcl1b, SNORA63
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Mcl1
Format:
Viral Particles
Storage:
-80 °C
Mouse MCL1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
NCBI Accession:
NM_008562
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5091020
Datasheet
Catalog No. ABIN5091020
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
NCBI Accession:
NM_008562
Species:
Mouse
Synonyms:
MCL1, Mcl1, mcl1a, mcl1b, SNORA63
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Mcl1
Format:
Viral Particles
Storage:
-80 °C
Human MCL1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4835109
Datasheet
Catalog No. ABIN4835109
Type:
cDNA
Application:
Cloning
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
Species:
Human
Synonyms:
MCL1, Mcl1, mcl1a, mcl1b, SNORA63
Insert length:
1053 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MCL1 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4705979
Datasheet
Catalog No. ABIN4705979
Type:
cDNA
Application:
Cloning
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
Species:
Human
Synonyms:
MCL1, Mcl1, mcl1a, mcl1b, SNORA63
Insert length:
1053 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MCL1 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4621388
Datasheet
Catalog No. ABIN4621388
Type:
cDNA
Application:
Cloning
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
Species:
Human
Synonyms:
MCL1, Mcl1, mcl1a, mcl1b, SNORA63
Insert length:
1053 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MCL1 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4439012
Datasheet
Catalog No. ABIN4439012
Type:
cDNA
Application:
Protein Expression
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
Species:
Human
Synonyms:
MCL1, Mcl1, mcl1a, mcl1b, SNORA63
Insert length:
1053 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse MCL1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
NCBI Accession:
NM_008562
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5725477
Datasheet
Catalog No. ABIN5725477
Type:
ORF
Application:
Cloning
Gene:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
NCBI Accession:
NM_008562
Species:
Mouse
Synonyms:
MCL1, Mcl1, mcl1a, mcl1b, SNORA63
Insert length:
996 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-U6-sgRNA-PGK-Neo
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pCMV6-XL4
    • pCMV6-XL6
    • pDONR223
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • SFFV Promoter
    • PGK Promoter
    • Enhanced CMV Promoter
    • SP6 Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to MCL-1

  • MCL1, BCL2 family apoptosis regulator (MCL1)
  • myeloid cell leukemia sequence 1 (Mcl1)
  • MCL1, BCL2 family apoptosis regulator (Mcl1)
  • MCL1, BCL2 family apoptosis regulator a (mcl1a)
  • MCL1, BCL2 family apoptosis regulator b (mcl1b)
  • small nucleolar RNA, H/ACA box 63 (SNORA63)
  • AW556805
  • bcl2-L-3
  • BCL2L3
  • E3
  • E3-2
  • EAT
  • elF-4AII
  • fb72f02
  • Mcl-1
  • mcl-1
  • MCL1-ES
  • mcl1/EAT
  • MCL1L
  • MCL1S
  • RNE3
  • RNU107
  • SNORA63A
  • TM
  • wu:fb70a08
  • wu:fb72f02
  • zfMcl-1a
  • zfMLP1
  • zgc:109763
  • zgc:109835

Gene-IDs for different species

Protein level used designations for MCL-1

  • bcl-2-like protein 3
  • bcl-2-related protein EAT/mcl1
  • induced myeloid leukemia cell differentiation protein Mcl-1
  • myeloid cell leukemia ES
  • induced myeloid leukemia cell differentiation protein Mcl-1 homolog
  • myeloid cell leukemia protein 1
  • fb70a08
  • BCL2 family apoptosis regulator
  • LOW QUALITY PROTEIN: induced myeloid leukemia cell differentiation protein Mcl-1
  • myeloid cell leukemia sequence 1 (BCL2-related)
  • RNA, U107 small nucleolar
  • RNA, small nucleolar E3
Other products related to MCL-1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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