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MCM4 (Minichromosome Maintenance Deficient 4, MCM4)

Short Description: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008].
More information related to gene MCM4.

Products related to MCM4 Gene:

53 results :

Human MCM4 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_005914
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5735896
Datasheet
Catalog No. ABIN5735896
Type:
ORF
Application:
Cloning
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_005914
Species:
Human
Synonyms:
mcm4.L, mcm4.S, MCM4, mcm4, Mcm4
Insert length:
2592 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse MCM4 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_008565
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5110095
Datasheet
Catalog No. ABIN5110095
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_008565
Species:
Mouse
Synonyms:
mcm4.L, mcm4.S, MCM4, mcm4, Mcm4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Mcm4
Format:
Viral Particles
Storage:
-80 °C
Human MCM4 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_005914
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5110093
Datasheet
Catalog No. ABIN5110093
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_005914
Species:
Human
Synonyms:
mcm4.L, mcm4.S, MCM4, mcm4, Mcm4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MCM4
Format:
Viral Particles
Storage:
-80 °C
Rat MCM4 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_033651
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5110097
Datasheet
Catalog No. ABIN5110097
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_033651
Species:
Rat
Synonyms:
mcm4.L, mcm4.S, MCM4, mcm4, Mcm4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Mcm4
Format:
Viral Particles
Storage:
-80 °C
Mouse MCM4 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_008565
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5735897
Datasheet
Catalog No. ABIN5735897
Type:
ORF
Application:
Cloning
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_008565
Species:
Mouse
Synonyms:
mcm4.L, mcm4.S, MCM4, mcm4, Mcm4
Insert length:
2589 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat MCM4 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_033651
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5735898
Datasheet
Catalog No. ABIN5735898
Type:
ORF
Application:
Cloning
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_033651
Species:
Rat
Synonyms:
mcm4.L, mcm4.S, MCM4, mcm4, Mcm4
Insert length:
2589 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat MCM4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_033651
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5225404
Datasheet
Catalog No. ABIN5225404
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_033651
Species:
Rat
Synonyms:
mcm4.L, mcm4.S, MCM4, mcm4, Mcm4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Mcm4
Format:
Viral Particles
Storage:
-80 °C
Mouse MCM4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_008565
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5225402
Datasheet
Catalog No. ABIN5225402
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_008565
Species:
Mouse
Synonyms:
mcm4.L, mcm4.S, MCM4, mcm4, Mcm4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Mcm4
Format:
Viral Particles
Storage:
-80 °C
Human MCM4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_005914
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5225400
Datasheet
Catalog No. ABIN5225400
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_005914
Species:
Human
Synonyms:
mcm4.L, mcm4.S, MCM4, mcm4, Mcm4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MCM4
Format:
Viral Particles
Storage:
-80 °C
Human MCM4 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_005914
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5110092
Datasheet
Catalog No. ABIN5110092
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Minichromosome Maintenance Deficient 4 (MCM4)
NCBI Accession:
NM_005914
Species:
Human
Synonyms:
mcm4.L, mcm4.S, MCM4, mcm4, Mcm4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of MCM4
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRS
    • pCMV6-XL4
    • pCMV6-XL5
    • pRFP-C-RS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to MCM4

  • minichromosome maintenance complex component 4 L homeolog (mcm4.L)
  • minichromosome maintenance complex component 4 S homeolog (mcm4.S)
  • minichromosome maintenance complex component 4 (MCM4)
  • minichromosome maintenance complex component 4 (mcm4)
  • minichromosome maintenance complex component 4 (Mcm4)
  • 19G
  • AI325074
  • AU045576
  • cb1025
  • cdc21
  • CDC21
  • Cdc21
  • CDC54
  • fc12c09
  • fj85g09
  • hCdc21
  • hm:zeh1616
  • mcdc21
  • Mcmd4
  • mKIAA4003
  • NKCD
  • NKGCD
  • P1-CDC21
  • wu:fc12c09
  • wu:fj85g09
  • zeh1616

Gene-IDs for different species

Protein level used designations for MCM4

  • DNA replication licensing factor mcm4-B
  • xMCM4-B
  • P1-CDC21-B
  • CDC21 homolog-B
  • minichromosome maintenance protein 4-B
  • CDC21 homolog-A
  • DNA replication licensing factor mcm4-A
  • P1-CDC21-A
  • minichromosome maintenance deficient 4
  • minichromosome maintenance protein 4-A
  • p98
  • xMCM4-A
  • CDC21 homolog
  • DNA replication licensing factor MCM4
  • homolog of S. pombe cell devision cycle 21
  • MCM4 minichromosome maintenance deficient 4
  • DNA replication licensing factor mcm4
  • minichromosome maintenance protein 4
  • P1-CDC21
  • mini chromosome maintenance deficient 4 homolog
  • minichromosome maintenance deficient 4 homolog
Other products related to MCM4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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