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MEK2 (Mitogen-Activated Protein Kinase Kinase 2, MAP2K2)

Short Description: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008].
More information related to gene MEK2.

Products related to MEK2 Gene:

61 results :

Human MAP2K2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5741557
Datasheet
Catalog No. ABIN5741557
Type:
ORF
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Species:
Human
Synonyms:
MAP2K2, Map2k2, MKK2, map2k2a, map2k2b
Insert length:
1203 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human MAP2K2 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4834964
Datasheet
Catalog No. ABIN4834964
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Species:
Human
Synonyms:
MAP2K2, Map2k2, MKK2, map2k2a, map2k2b
Insert length:
1203 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MAP2K2 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4705834
Datasheet
Catalog No. ABIN4705834
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Species:
Human
Synonyms:
MAP2K2, Map2k2, MKK2, map2k2a, map2k2b
Insert length:
1203 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MAP2K2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4477837
Datasheet
Catalog No. ABIN4477837
Type:
cDNA
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Species:
Human
Synonyms:
MAP2K2, Map2k2, MKK2, map2k2a, map2k2b
Insert length:
1203 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat MAP2K2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
NCBI Accession:
NM_133283
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120770
Datasheet
Catalog No. ABIN5120770
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
NCBI Accession:
NM_133283
Species:
Rat
Synonyms:
MAP2K2, Map2k2, MKK2, map2k2a, map2k2b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Map2k2
Format:
Viral Particles
Storage:
-80 °C
Mouse MAP2K2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
NCBI Accession:
NM_023138
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120768
Datasheet
Catalog No. ABIN5120768
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
NCBI Accession:
NM_023138
Species:
Mouse
Synonyms:
MAP2K2, Map2k2, MKK2, map2k2a, map2k2b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Map2k2
Format:
Viral Particles
Storage:
-80 °C
Human MAP2K2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
NCBI Accession:
NM_030662
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120766
Datasheet
Catalog No. ABIN5120766
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
NCBI Accession:
NM_030662
Species:
Human
Synonyms:
MAP2K2, Map2k2, MKK2, map2k2a, map2k2b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MAP2K2
Format:
Viral Particles
Storage:
-80 °C
Human MAP2K2 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4834965
Datasheet
Catalog No. ABIN4834965
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Species:
Human
Synonyms:
MAP2K2, Map2k2, MKK2, map2k2a, map2k2b
Insert length:
1203 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MAP2K2 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4621308
Datasheet
Catalog No. ABIN4621308
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Species:
Human
Synonyms:
MAP2K2, Map2k2, MKK2, map2k2a, map2k2b
Insert length:
1203 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MAP2K2 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4438932
Datasheet
Catalog No. ABIN4438932
Type:
cDNA
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Species:
Human
Synonyms:
MAP2K2, Map2k2, MKK2, map2k2a, map2k2b
Insert length:
1203 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • His-GST
    • His-MBP
    • HA tag
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pPB-His-GST
    • pPB-His-MBP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pCMV6-XL5
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to MEK2

  • mitogen-activated protein kinase kinase 2 (MAP2K2)
  • mitogen-activated protein kinase kinase 2 (Map2k2)
  • mitogen activated protein kinase kinase 2 (Map2k2)
  • MAP kinase kinase 2 (MKK2)
  • mitogen-activated protein kinase kinase 2a (map2k2a)
  • mitogen-activated protein kinase kinase 2b (map2k2b)
  • AA589381
  • ATMKK2
  • CFC4
  • F27B13.50
  • F27B13_50
  • map2k2
  • MAP KINASE KINASE 1
  • MAP kinase kinase 2
  • MAPKK2
  • MEK2
  • MK1
  • MK2
  • MKK2
  • PRKMK2
  • Prkmk2
  • wu:fa56c06
  • zgc:123171
  • zgc:172250

Gene-IDs for different species

Protein level used designations for MEK2

  • ERK activator kinase 2
  • MAP kinase kinase 2
  • MAPK/ERK kinase 2
  • dual specificity mitogen-activated protein kinase kinase 2
  • mitogen-activated protein kinase kinase 2, p45
  • MAP kinase/Erk kinase
  • MAPKK 2
  • MEK 2
  • mitogen activated protein kinase kinase 2
  • protein kinase, mitogen activated, kinase 2, p45
  • MEK2
  • mitogen-activated protein kinase kinase type 2
  • dual specificity mitogen activated protein kinase kinase 2
  • fa56c06
  • mitogen-activated protein kinase kinase 2
Other products related to MEK2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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