MKNK2 (MAP Kinase Interacting serine/threonine Kinase 2, MKNK2)
Short Description: This gene encodes a member of the calcium/calmodulin-dependent protein kinases (CAMK) Ser/Thr protein kinase family, which belongs to the protein kinase superfamily. This protein contains conserved DLG (asp-leu-gly) and ENIL (glu-asn-ile-leu) motifs, and an N-terminal polybasic region which binds importin A and the translation factor scaffold protein eukaryotic initiation factor 4G (eIF4G). This protein is one of the downstream kinases activated by mitogen-activated protein (MAP) kinases. It phosphorylates the eukaryotic initiation factor 4E (eIF4E), thus playing important roles in the initiation of mRNA translation, oncogenic transformation and malignant cell proliferation. In addition to eIF4E, this protein also interacts with von Hippel-Lindau tumor suppressor (VHL), ring-box 1 (Rbx1) and Cullin2 (Cul2), which are all components of the CBC(VHL) ubiquitin ligase E3 complex. Multiple alternatively spliced transcript variants have been found, but the full-length nature and biological activity of only two variants are determined. These two variants encode distinct isoforms which differ in activity and regulation, and in subcellular localization. [provided by RefSeq, Aug 2011].
More information related to gene MKNK2.
More information related to gene MKNK2.
Products related to MKNK2 Gene:
Recommended next Filters:
69 results
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- NCBI Accession:
- NM_017572
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5236057
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- NCBI Accession:
- NM_001011985
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5236061
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5313962
$212.22
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 19 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- NCBI Accession:
- NM_017572
- Gene ID:
- 2872 (Human, MKNK2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4937679
$379.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- NCBI Accession:
- NM_199054
- Gene ID:
- 2872 (Human, MKNK2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4937678
$389.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene mc208964
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- NCBI Accession:
- NM_021462,NP_067437
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3330572
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rn204301
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- NCBI Accession:
- NM_001011985,NP_001011985
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3330573
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rr204301
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- NCBI Accession:
- NM_001011985,NP_001011985
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5404973
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr413678
RNAi
MKNK2
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3269754
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr504015
RNAi
MKNK2
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3353988
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to MKNK2
- MAP kinase interacting serine/threonine kinase 2 (MKNK2)
- MAP kinase interacting serine/threonine kinase 2 (mknk2)
- MAP kinase-interacting serine/threonine kinase 2 (Mknk2)
- MAP kinase interacting serine/threonine kinase 2b (mknk2b)
- MAP kinase interacting serine/threonine kinase 2 L homeolog (mknk2.L)
- MAP kinase interacting serine/threonine kinase 2 (Mknk2)
- MAP kinase interacting serine/threonine kinase 2a (mknk2a)
- 2010016G11Rik
- fi34c11
- GPRK7
- gprk7
- Gprk7
- mknk2
- MNK2
- mnk2
- Mnk2
- wu:fb37e05
- wu:fi34c11
- wu:fi41e12
- wz5090
- zgc:55587
Gene-IDs for different species
Protein level used designations for MKNK2
- G protein-coupled receptor kinase 7
- MAP kinase signal-integrating kinase 2
- MAP kinase-interacting serine/threonine-protein kinase 2
- MAPK signal-integrating kinase 2
- MAP kinase interacting serine/threonine kinase 2
- MAP kinase-interacting serine/threonine kinase 2
- mnk2
- MAP kinase interacting serine/threonine kinase 2a
Proteomics products related to MKNK2 Gene
Other products related to MKNK2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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