MKNK2 (MAP Kinase Interacting serine/threonine Kinase 2, MKNK2)
Short Description: This gene encodes a member of the calcium/calmodulin-dependent protein kinases (CAMK) Ser/Thr protein kinase family, which belongs to the protein kinase superfamily. This protein contains conserved DLG (asp-leu-gly) and ENIL (glu-asn-ile-leu) motifs, and an N-terminal polybasic region which binds importin A and the translation factor scaffold protein eukaryotic initiation factor 4G (eIF4G). This protein is one of the downstream kinases activated by mitogen-activated protein (MAP) kinases. It phosphorylates the eukaryotic initiation factor 4E (eIF4E), thus playing important roles in the initiation of mRNA translation, oncogenic transformation and malignant cell proliferation. In addition to eIF4E, this protein also interacts with von Hippel-Lindau tumor suppressor (VHL), ring-box 1 (Rbx1) and Cullin2 (Cul2), which are all components of the CBC(VHL) ubiquitin ligase E3 complex. Multiple alternatively spliced transcript variants have been found, but the full-length nature and biological activity of only two variants are determined. These two variants encode distinct isoforms which differ in activity and regulation, and in subcellular localization. [provided by RefSeq, Aug 2011].
More information related to gene MKNK2.
More information related to gene MKNK2.
Products related to MKNK2 Gene:
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69 results
OriGene sr504015
RNAi
MKNK2
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3353988
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene kn510126
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3242950
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn410081
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3242949
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene mc208964
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- NCBI Accession:
- NM_021462,NP_067437
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3330572
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rn204301
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- NCBI Accession:
- NM_001011985,NP_001011985
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3330573
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc315549
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL4
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- NCBI Accession:
- NM_017572,NP_060042
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL4
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3378911
$679.14
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc307857
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL6
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- NCBI Accession:
- NM_199054,NP_951009
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL6
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, SP6 Promoter
- Expression:
- Transient
Catalog No. ABIN3393639
$679.14
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- NCBI Accession:
- NM_199054
- Gene ID:
- 2872 (Human, MKNK2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4937678
$389.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- NCBI Accession:
- NM_017572
- Gene ID:
- 2872 (Human, MKNK2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4937679
$379.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene rg210081
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5404969
$877.14
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
Synonyms and alternative names related to MKNK2
- MAP kinase interacting serine/threonine kinase 2 (MKNK2)
- MAP kinase interacting serine/threonine kinase 2 (mknk2)
- MAP kinase-interacting serine/threonine kinase 2 (Mknk2)
- MAP kinase interacting serine/threonine kinase 2b (mknk2b)
- MAP kinase interacting serine/threonine kinase 2 L homeolog (mknk2.L)
- MAP kinase interacting serine/threonine kinase 2 (Mknk2)
- MAP kinase interacting serine/threonine kinase 2a (mknk2a)
- 2010016G11Rik
- fi34c11
- GPRK7
- gprk7
- Gprk7
- mknk2
- MNK2
- mnk2
- Mnk2
- wu:fb37e05
- wu:fi34c11
- wu:fi41e12
- wz5090
- zgc:55587
Gene-IDs for different species
Protein level used designations for MKNK2
- G protein-coupled receptor kinase 7
- MAP kinase signal-integrating kinase 2
- MAP kinase-interacting serine/threonine-protein kinase 2
- MAPK signal-integrating kinase 2
- MAP kinase interacting serine/threonine kinase 2
- MAP kinase-interacting serine/threonine kinase 2
- mnk2
- MAP kinase interacting serine/threonine kinase 2a
Proteomics products related to MKNK2 Gene
Other products related to MKNK2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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