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MKNK2 (MAP Kinase Interacting serine/threonine Kinase 2, MKNK2)

Short Description: This gene encodes a member of the calcium/calmodulin-dependent protein kinases (CAMK) Ser/Thr protein kinase family, which belongs to the protein kinase superfamily. This protein contains conserved DLG (asp-leu-gly) and ENIL (glu-asn-ile-leu) motifs, and an N-terminal polybasic region which binds importin A and the translation factor scaffold protein eukaryotic initiation factor 4G (eIF4G). This protein is one of the downstream kinases activated by mitogen-activated protein (MAP) kinases. It phosphorylates the eukaryotic initiation factor 4E (eIF4E), thus playing important roles in the initiation of mRNA translation, oncogenic transformation and malignant cell proliferation. In addition to eIF4E, this protein also interacts with von Hippel-Lindau tumor suppressor (VHL), ring-box 1 (Rbx1) and Cullin2 (Cul2), which are all components of the CBC(VHL) ubiquitin ligase E3 complex. Multiple alternatively spliced transcript variants have been found, but the full-length nature and biological activity of only two variants are determined. These two variants encode distinct isoforms which differ in activity and regulation, and in subcellular localization. [provided by RefSeq, Aug 2011].
More information related to gene MKNK2.

Products related to MKNK2 Gene:

69 results :

Human MKNK2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5741507
Datasheet
Catalog No. ABIN5741507
Type:
ORF
Application:
Cloning
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
Species:
Human
Synonyms:
MKNK2, mknk2, Mknk2, mknk2b, mknk2.L, mknk2a
Insert length:
477 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human MKNK2 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA PExp Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Protein Expression
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN5772722
Datasheet
Catalog No. ABIN5772722
Type:
cDNA
Application:
Protein Expression
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
Species:
Human
Synonyms:
MKNK2, mknk2, Mknk2, mknk2b, mknk2.L, mknk2a
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human MKNK2 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA PExp Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Protein Expression
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN5772721
Datasheet
Catalog No. ABIN5772721
Type:
cDNA
Application:
Protein Expression
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
Species:
Human
Synonyms:
MKNK2, mknk2, Mknk2, mknk2b, mknk2.L, mknk2a
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human MKNK2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4478099
Datasheet
Catalog No. ABIN4478099
Type:
cDNA
Application:
Protein Expression
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
Species:
Human
Synonyms:
MKNK2, mknk2, Mknk2, mknk2b, mknk2.L, mknk2a
Insert length:
477 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat MKNK2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
NCBI Accession:
NM_001011985
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5236062
Datasheet
Catalog No. ABIN5236062
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
NCBI Accession:
NM_001011985
Species:
Rat
Synonyms:
MKNK2, mknk2, Mknk2, mknk2b, mknk2.L, mknk2a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Mknk2
Format:
Viral Particles
Storage:
-80 °C
Mouse MKNK2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
NCBI Accession:
NM_021462
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5236060
Datasheet
Catalog No. ABIN5236060
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
NCBI Accession:
NM_021462
Species:
Mouse
Synonyms:
MKNK2, mknk2, Mknk2, mknk2b, mknk2.L, mknk2a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Mknk2
Format:
Viral Particles
Storage:
-80 °C
Human MKNK2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
NCBI Accession:
NM_017572
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5236058
Datasheet
Catalog No. ABIN5236058
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
NCBI Accession:
NM_017572
Species:
Human
Synonyms:
MKNK2, mknk2, Mknk2, mknk2b, mknk2.L, mknk2a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MKNK2
Format:
Viral Particles
Storage:
-80 °C
Rat MKNK2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
NCBI Accession:
NM_001011985
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120696
Datasheet
Catalog No. ABIN5120696
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
NCBI Accession:
NM_001011985
Species:
Rat
Synonyms:
MKNK2, mknk2, Mknk2, mknk2b, mknk2.L, mknk2a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Mknk2
Format:
Viral Particles
Storage:
-80 °C
Mouse MKNK2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
NCBI Accession:
NM_021462
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120694
Datasheet
Catalog No. ABIN5120694
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
NCBI Accession:
NM_021462
Species:
Mouse
Synonyms:
MKNK2, mknk2, Mknk2, mknk2b, mknk2.L, mknk2a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Mknk2
Format:
Viral Particles
Storage:
-80 °C
Human MKNK2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
NCBI Accession:
NM_017572
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120692
Datasheet
Catalog No. ABIN5120692
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2)
NCBI Accession:
NM_017572
Species:
Human
Synonyms:
MKNK2, mknk2, Mknk2, mknk2b, mknk2.L, mknk2a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MKNK2
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • His-GST
    • His-MBP
    • HA tag
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pPB-His-GST
    • pPB-His-MBP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL4
    • pCMV6-XL6
    • pDONR223
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • SP6 Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to MKNK2

  • MAP kinase interacting serine/threonine kinase 2 (MKNK2)
  • MAP kinase interacting serine/threonine kinase 2 (mknk2)
  • MAP kinase-interacting serine/threonine kinase 2 (Mknk2)
  • MAP kinase interacting serine/threonine kinase 2b (mknk2b)
  • MAP kinase interacting serine/threonine kinase 2 L homeolog (mknk2.L)
  • MAP kinase interacting serine/threonine kinase 2 (Mknk2)
  • MAP kinase interacting serine/threonine kinase 2a (mknk2a)
  • 2010016G11Rik
  • fi34c11
  • GPRK7
  • gprk7
  • Gprk7
  • mknk2
  • MNK2
  • mnk2
  • Mnk2
  • wu:fb37e05
  • wu:fi34c11
  • wu:fi41e12
  • wz5090
  • zgc:55587

Gene-IDs for different species

Protein level used designations for MKNK2

  • G protein-coupled receptor kinase 7
  • MAP kinase signal-integrating kinase 2
  • MAP kinase-interacting serine/threonine-protein kinase 2
  • MAPK signal-integrating kinase 2
  • MAP kinase interacting serine/threonine kinase 2
  • MAP kinase-interacting serine/threonine kinase 2
  • mnk2
  • MAP kinase interacting serine/threonine kinase 2a
Other products related to MKNK2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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