p300 (E1A Binding Protein P300, EP300)

Short Description: This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008].
More information related to gene p300.
Products related to p300 Gene:
56 Products
Type
  • 53
  • 3
Species
  • 30
  • 26
Application
  • 27
  • 17
  • 12
  • 8
Fusion tag
  • 19
  • 7
  • 6
  • 6
  • 5
Vector Backbone
  • 4
  • 4
  • 4
  • 2
  • 2
Vector
  • 18
  • 17
  • 8
  • 6
  • 4
Insert
  • 20
  • 14
  • 7
  • 6
  • 4
Oligo-Type
  • 3
Resistance Gene
  • 24
  • 21
  • 6
  • 2
  • 2
Expression Type
  • 51
  • 34
Selectable Marker
  • 18
  • 17
  • 2
Promoter
  • 22
  • 15
  • 9
  • 6
  • 4
Format
  • 21
  • 18
  • 12
  • 5

Type:
cDNA
Application:
Cloning
Gene:
E1A Binding Protein P300 (EP300)
Gene ID:
328572 (Mouse (Murine), EP300)
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Cloning Vector
Vector backbone:
pCR-XL-TOPO
Resistance Gene:
Kanamycin
Selection Marker:
Bleomycin

Sequencing Primer:
  • T7
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3998145
$118.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Cloning
Gene:
E1A Binding Protein P300 (EP300)
Gene ID:
328572 (Mouse (Murine), EP300)
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Cloning Vector
Vector backbone:
pCR-XL-TOPO
Resistance Gene:
Kanamycin
Selection Marker:
Bleomycin

Sequencing Primer:
  • T7
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3998146
$162.44
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Application:
RNA Interference
Gene:
E1A Binding Protein P300
Species:
Mouse (Murine)
Synonyms:
KAT3B, RSTS2, p300, A430090G16, A730011L11, p300 HAT
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • Ep300 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3350328
$420.00
1 kit
Plus shipping costs $45.00
Delivery in 4 to 8 Business Days

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
E1A Binding Protein P300 (EP300)
NCBI Accession:
NM_001429
Species:
Human
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of EP300
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5087774
$420.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
E1A Binding Protein P300 (EP300)
NCBI Accession:
NM_177821
Species:
Mouse (Murine)
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ep300
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5087776
$420.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available

Type:
gRNA + gRNA
Application:
Genome Editing with Engineered Nucleases
Gene:
E1A Binding Protein P300 (EP300)
Gene ID:
2033 (Human, EP300)
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Lentiviral Vector
Vector backbone:
pCLIP-dual-SFFV-ZsGreen
Resistance Gene:
Ampicillin, Zeocin
Selection Marker:
Puromycin
Promoter:
SFFV Promoter, U6 Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Viral particles:
ABIN5051051

Components:
- Two vectors containing two gRNAs in each vector
- Negative control
- Available as bacterial glycerol stocks or viral particles
- Cas9 expression vectors can be purchased separately
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN5032106
$503.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Application:
RNA Interference
Gene:
E1A Binding Protein P300
Gene ID:
328572 (Mouse (Murine), EP300)
Synonyms:
KAT3B, RSTS2, p300, A430090G16, A730011L11, p300 HAT
Purification:
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Components:
This product is provided as two 5 nmol vials (10 nmol), three 5 nmol vials (15 nmol) or 2x three 5 nmol vials (30 nmol) of lyophilized siRNA oligo duplexes. Each vial contains slightly different sequences to ensure full knockout of the gene. Each vial contains slightly different sequences to ensure full knockout of the gene. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. The siRNA oligos are also chemically modified (2'-OMe) for increased stability and enhanced knockdown in vitro and in vivo.
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5783511
$516.85
Plus shipping costs $45.00
Delivery in 16 to 26 Business Days

Application:
RNA Interference
Gene:
E1A Binding Protein P300
Gene ID:
2033 (Human, EP300)
Synonyms:
KAT3B, RSTS2, p300, A430090G16, A730011L11, p300 HAT
Purification:
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Components:
This product is provided as two 5 nmol vials (10 nmol), three 5 nmol vials (15 nmol) or 2x three 5 nmol vials (30 nmol) of lyophilized siRNA oligo duplexes. Each vial contains slightly different sequences to ensure full knockout of the gene. Each vial contains slightly different sequences to ensure full knockout of the gene. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. The siRNA oligos are also chemically modified (2'-OMe) for increased stability and enhanced knockdown in vitro and in vivo.
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5783512
$516.85
Plus shipping costs $45.00
Delivery in 16 to 26 Business Days

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
E1A Binding Protein P300 (EP300)
NCBI Accession:
NM_001429
Species:
Human
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of EP300
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5202920
$520.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
E1A Binding Protein P300 (EP300)
NCBI Accession:
NM_177821
Species:
Mouse (Murine)
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ep300
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5202922
$520.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available

Type:
shRNA
Application:
RNA Interference
Gene:
E1A Binding Protein P300 (EP300)
Gene ID:
2033 (Human, EP300)
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Lentiviral Vector
Vector backbone:
pZIP-mCMV-ZsGreen
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
mCMV Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Empty vector controls:
ABIN5691888
Viral particles:
ABIN3478207

Components:
3 separate shRNA clones and a non-targeting control
Format:
Glycerol Stock
Buffer:
E. coli bacterial culture in LB-Lennox (low salt) broth with 8 % glycerol.
Storage:
-80 °C
Catalog No. ABIN3478206
$703.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
E1A Binding Protein P300 (EP300)
Gene ID:
328572 (Mouse (Murine), EP300)
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Lentiviral Vector
Vector backbone:
pZIP-mCMV-ZsGreen
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
mCMV Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Empty vector controls:
ABIN5691888
Viral particles:
ABIN3478207

Components:
3 separate shRNA clones and a non-targeting control
Format:
Glycerol Stock
Buffer:
E. coli bacterial culture in LB-Lennox (low salt) broth with 8 % glycerol.
Storage:
-80 °C
Catalog No. ABIN4188319
$703.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
E1A Binding Protein P300 (EP300)
Species:
Human
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable

Empty vector controls:
ABIN4948187

Components:
  • Gene-specific shRNA in pGFPC-shLenti vector, 4 unique constructs per gene, 5 ug per vial.
  • HuSH 29-mer Scrambled in pGFP-C-shLenti 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3738038
$715.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
E1A Binding Protein P300 (EP300)
Species:
Human
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable

Empty vector controls:
ABIN4948189

Components:
  • Gene-specific shRNA expression pRS vectors, 5 ug plasmid DNA per vial.
  • Four unique constructs per gene.
  • HuSH 29-mer NonEffective Scrambled pRS 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3655136
$715.00
1 kit
Plus shipping costs $45.00
Delivery in 4 to 8 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
E1A Binding Protein P300 (EP300)
Species:
Mouse (Murine)
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable

Empty vector controls:
ABIN4948188

Components:
  • Gene-specific shRNA expression pRFP-C-RS vectors, 5 ug plasmid DNA per vial.
  • Four unique constructs per gene.
  • HuSH 29-mer NonEffective Scrambled pGFP-VRS 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3678175
$715.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
E1A Binding Protein P300 (EP300)
Species:
Mouse (Murine)
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable

Empty vector controls:
ABIN4948187

Components:
  • Gene-specific shRNA in pGFPC-shLenti vector, 4 unique constructs per gene, 5 ug per vial.
  • HuSH 29-mer Scrambled in pGFP-C-shLenti 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3697874
$715.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
E1A Binding Protein P300 (EP300)
Species:
Human
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable

Empty vector controls:
ABIN4948188

Components:
  • Gene-specific shRNA expression pRFP-C-RS vectors, 5 ug plasmid DNA per vial.
  • Four unique constructs per gene.
  • HuSH 29-mer NonEffective Scrambled pGFP-VRS 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3717699
$715.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
E1A Binding Protein P300 (EP300)
Species:
Mouse (Murine)
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable

Empty vector controls:
ABIN4948189

Components:
  • Gene-specific shRNA expression pRS vectors, 5 ug plasmid DNA per vial.
  • Four unique constructs per gene.
  • HuSH 29-mer NonEffective Scrambled pRS 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3548882
$715.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
E1A Binding Protein P300 (EP300)
Gene ID:
2033 (Human, EP300)
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Mammalian Expression Vector
Vector backbone:
pU6-GFP-Neo
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter, U6 Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient

Components:
This product contains 3 separate slightly different shRNA sequences which knock down human EP300 gene specifically. Each vial contains 50 μg of lyophilized shRNA.
Format:
Lyophilized
Storage:
4 °C,-20 °C,-80 °C
Catalog No. ABIN5808370
$749.44
Plus shipping costs $45.00
Delivery in 16 to 26 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
E1A Binding Protein P300 (EP300)
Gene ID:
328572 (Mouse (Murine), EP300)
Synonyms:
EP300, LOC446056, ep300, Ep300
Vector type:
Mammalian Expression Vector
Vector backbone:
pU6-GFP-Neo
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter, U6 Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient

Components:
This product contains 3 separate slightly different shRNA sequences which knock down mouse EP300 gene specifically. Each vial contains 50 μg of lyophilized shRNA.
Format:
Lyophilized
Storage:
4 °C,-20 °C,-80 °C
Catalog No. ABIN5808371
$749.44
Plus shipping costs $45.00
Delivery in 16 to 26 Business Days
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Synonyms and alternative names related to p300

  • E1A binding protein p300 (EP300)
  • histone acetyltransferase p300 (LOC446056)
  • E1A binding protein p300 (ep300)
  • E1A binding protein p300 (Ep300)
  • A430090G16
  • A730011L11
  • KAT3B
  • p300
  • p300 HAT
  • RSTS2

Gene-IDs for different species

GENE IDSPECIES
100055626 Equus caballus
458862 Pan troglodytes
706258 Macaca mulatta
446056 Takifugu rubripes
100028102 Monodelphis domestica
100455260 Pongo abelii
100468694 Ailuropoda melanoleuca
100543704 Meleagris gallopavo
100566746 Anolis carolinensis
2033 Homo sapiens
328572 Mus musculus
418000 Gallus gallus
100684945 Canis lupus familiaris
100156226 Sus scrofa
170915 Rattus norvegicus
100734820 Cavia porcellus

Protein level used designations for p300

  • histone acetyltransferase p300
  • histone acetyltransferase
  • E1A binding protein p300
  • histone acetyltransferase p300-like
  • E1A-associated protein p300
  • E1A-binding protein, 300kD
  • p300 HAT
Other products related to p300 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com