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PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase, PAICS)

Short Description: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene PAICS.

Products related to PAICS Gene:

66 results :

Human PAICS ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5751534
Datasheet
Catalog No. ABIN5751534
Type:
ORF
Application:
Cloning
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
Species:
Human
Synonyms:
PAICS, paics, LOC551966, Tsp_02239a, Tsp_02239, CNE02500, purC/E, Paics, paics.2.L
Insert length:
1278 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human PAICS cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4479077
Datasheet
Catalog No. ABIN4479077
Type:
cDNA
Application:
Protein Expression
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
Species:
Human
Synonyms:
PAICS, paics, LOC551966, Tsp_02239a, Tsp_02239, CNE02500, purC/E, Paics, paics.2.L
Insert length:
1278 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat PAICS CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
NCBI Accession:
NM_080910
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5255531
Datasheet
Catalog No. ABIN5255531
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
NCBI Accession:
NM_080910
Species:
Rat
Synonyms:
PAICS, paics, LOC551966, Tsp_02239a, Tsp_02239, CNE02500, purC/E, Paics, paics.2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Paics
Format:
Viral Particles
Storage:
-80 °C
Mouse PAICS CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
NCBI Accession:
NM_025939
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5255529
Datasheet
Catalog No. ABIN5255529
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
NCBI Accession:
NM_025939
Species:
Mouse
Synonyms:
PAICS, paics, LOC551966, Tsp_02239a, Tsp_02239, CNE02500, purC/E, Paics, paics.2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Paics
Format:
Viral Particles
Storage:
-80 °C
Human PAICS CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
NCBI Accession:
NM_001079524
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5255527
Datasheet
Catalog No. ABIN5255527
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
NCBI Accession:
NM_001079524
Species:
Human
Synonyms:
PAICS, paics, LOC551966, Tsp_02239a, Tsp_02239, CNE02500, purC/E, Paics, paics.2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PAICS
Format:
Viral Particles
Storage:
-80 °C
Mouse PAICS CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
NCBI Accession:
NM_025939
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5140036
Datasheet
Catalog No. ABIN5140036
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
NCBI Accession:
NM_025939
Species:
Mouse
Synonyms:
PAICS, paics, LOC551966, Tsp_02239a, Tsp_02239, CNE02500, purC/E, Paics, paics.2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Paics
Format:
Viral Particles
Storage:
-80 °C
Human PAICS CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
NCBI Accession:
NM_001079524
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5140034
Datasheet
Catalog No. ABIN5140034
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
NCBI Accession:
NM_001079524
Species:
Human
Synonyms:
PAICS, paics, LOC551966, Tsp_02239a, Tsp_02239, CNE02500, purC/E, Paics, paics.2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PAICS
Format:
Viral Particles
Storage:
-80 °C
Rat PAICS CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
NCBI Accession:
NM_080910
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5140038
Datasheet
Catalog No. ABIN5140038
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
NCBI Accession:
NM_080910
Species:
Rat
Synonyms:
PAICS, paics, LOC551966, Tsp_02239a, Tsp_02239, CNE02500, purC/E, Paics, paics.2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Paics
Format:
Viral Particles
Storage:
-80 °C
Human PAICS cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4837001
Datasheet
Catalog No. ABIN4837001
Type:
cDNA
Application:
Cloning
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
Species:
Human
Synonyms:
PAICS, paics, LOC551966, Tsp_02239a, Tsp_02239, CNE02500, purC/E, Paics, paics.2.L
Insert length:
1278 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PAICS cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4622548
Datasheet
Catalog No. ABIN4622548
Type:
cDNA
Application:
Cloning
Gene:
phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS)
Species:
Human
Synonyms:
PAICS, paics, LOC551966, Tsp_02239a, Tsp_02239, CNE02500, purC/E, Paics, paics.2.L
Insert length:
1278 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PAICS

  • phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase (PAICS)
  • phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (paics)
  • multifunctional protein ADE2 (LOC551966)
  • multifunctional protein ADE2 (Tsp_02239a)
  • multifunctional protein ADE2 (Tsp_02239)
  • phosphoribosylaminoimidazole carboxylase (CNE02500)
  • phosphoribosylaminoimidazole carboxylase (purC/E)
  • phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS)
  • phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase (Paics)
  • phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, gene 2 L homeolog (paics.2.L)
  • phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase (Paics)
  • 2610511I09Rik
  • ADE2
  • ade2
  • ADE2H1
  • Ade2h1
  • AIRC
  • Airc
  • airc
  • AS
  • cb293
  • DDBDRAFT_0218550
  • DDBDRAFT_0230088
  • DDB_0218550
  • DDB_0230088
  • GB14262
  • paics
  • PAIS
  • pais
  • sb:cb293
  • wu:fa28a05

Gene-IDs for different species

Protein level used designations for PAICS

  • multifunctional protein ADE2
  • phosphoribosylaminoimidazole carboxylase
  • phosphoribosylaminoimidazolesuccinocarboxamide synthase
  • AIR carboxylase domain
  • AIR carboxylase
  • SAICAR synthetase
  • multifunctional protein ADE2H1
  • phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole succinocarboxamide synthetase
  • Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase
Other products related to PAICS such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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