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PC (Pyruvate Carboxylase, PC)

Short Description: This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene PC.

Products related to PC Gene:

35 results :

Mouse PC CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_008797
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5096198
Datasheet
Catalog No. ABIN5096198
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_008797
Species:
Mouse
Synonyms:
PCB, pcxb, pyc-1, PC, pyc, pyr1, CNF00650, PYC1, Ndas_1152, Ilyop_2503, Calni_0495, Ftrac_1004, Plabr_3574, Sgly_2936, Celly_0558, Hipma_0131, Halhy_1567, Mesop_1269, Pcx, Pc
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pcx
Format:
Viral Particles
Storage:
-80 °C
Mouse PC ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_008797
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5728402
Datasheet
Catalog No. ABIN5728402
Type:
ORF
Application:
Cloning
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_008797
Species:
Mouse
Synonyms:
PCB, pcxb, pyc-1, PC, pyc, pyr1, CNF00650, PYC1, Ndas_1152, Ilyop_2503, Calni_0495, Ftrac_1004, Plabr_3574, Sgly_2936, Celly_0558, Hipma_0131, Halhy_1567, Mesop_1269, Pcx, Pc
Insert length:
3537 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse PC ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_001162946
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5728403
Datasheet
Catalog No. ABIN5728403
Type:
ORF
Application:
Cloning
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_001162946
Species:
Mouse
Synonyms:
PCB, pcxb, pyc-1, PC, pyc, pyr1, CNF00650, PYC1, Ndas_1152, Ilyop_2503, Calni_0495, Ftrac_1004, Plabr_3574, Sgly_2936, Celly_0558, Hipma_0131, Halhy_1567, Mesop_1269, Pcx, Pc
Insert length:
3540 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse PC CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_008797
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5211428
Datasheet
Catalog No. ABIN5211428
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_008797
Species:
Mouse
Synonyms:
PCB, pcxb, pyc-1, PC, pyc, pyr1, CNF00650, PYC1, Ndas_1152, Ilyop_2503, Calni_0495, Ftrac_1004, Plabr_3574, Sgly_2936, Celly_0558, Hipma_0131, Halhy_1567, Mesop_1269, Pcx, Pc
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pcx
Format:
Viral Particles
Storage:
-80 °C
Mouse PC CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_008797
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5096197
Datasheet
Catalog No. ABIN5096197
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_008797
Species:
Mouse
Synonyms:
PCB, pcxb, pyc-1, PC, pyc, pyr1, CNF00650, PYC1, Ndas_1152, Ilyop_2503, Calni_0495, Ftrac_1004, Plabr_3574, Sgly_2936, Celly_0558, Hipma_0131, Halhy_1567, Mesop_1269, Pcx, Pc
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Pcx
Format:
Viral Particles
Storage:
-80 °C
Mouse PC CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_008797
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5211427
Datasheet
Catalog No. ABIN5211427
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_008797
Species:
Mouse
Synonyms:
PCB, pcxb, pyc-1, PC, pyc, pyr1, CNF00650, PYC1, Ndas_1152, Ilyop_2503, Calni_0495, Ftrac_1004, Plabr_3574, Sgly_2936, Celly_0558, Hipma_0131, Halhy_1567, Mesop_1269, Pcx, Pc
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Pcx
Format:
Viral Particles
Storage:
-80 °C
Mouse PC cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_008797
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4452321
Datasheet
Catalog No. ABIN4452321
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_008797
Species:
Mouse
Synonyms:
PCB, pcxb, pyc-1, PC, pyc, pyr1, CNF00650, PYC1, Ndas_1152, Ilyop_2503, Calni_0495, Ftrac_1004, Plabr_3574, Sgly_2936, Celly_0558, Hipma_0131, Halhy_1567, Mesop_1269, Pcx, Pc
Insert length:
3537 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse PC cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_001162946
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4452322
Datasheet
Catalog No. ABIN4452322
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_001162946
Species:
Mouse
Synonyms:
PCB, pcxb, pyc-1, PC, pyc, pyr1, CNF00650, PYC1, Ndas_1152, Ilyop_2503, Calni_0495, Ftrac_1004, Plabr_3574, Sgly_2936, Celly_0558, Hipma_0131, Halhy_1567, Mesop_1269, Pcx, Pc
Insert length:
3540 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse PC cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_001162946
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4861120
Datasheet
Catalog No. ABIN4861120
Type:
cDNA
Application:
Cloning
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_001162946
Species:
Mouse
Synonyms:
PCB, pcxb, pyc-1, PC, pyc, pyr1, CNF00650, PYC1, Ndas_1152, Ilyop_2503, Calni_0495, Ftrac_1004, Plabr_3574, Sgly_2936, Celly_0558, Hipma_0131, Halhy_1567, Mesop_1269, Pcx, Pc
Insert length:
4148 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse PC cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_008797
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4861119
Datasheet
Catalog No. ABIN4861119
Type:
cDNA
Application:
Cloning
Gene:
Pyruvate Carboxylase (PC)
NCBI Accession:
NM_008797
Species:
Mouse
Synonyms:
PCB, pcxb, pyc-1, PC, pyc, pyr1, CNF00650, PYC1, Ndas_1152, Ilyop_2503, Calni_0495, Ftrac_1004, Plabr_3574, Sgly_2936, Celly_0558, Hipma_0131, Halhy_1567, Mesop_1269, Pcx, Pc
Insert length:
4125 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
  • Reactivity
    • Mouse
    • Human
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRFP-C-RS
    • pRS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PC

  • Pyruvate carboxylase (PCB)
  • pyruvate carboxylase b (pcxb)
  • PYruvate Carboxylase (pyc-1)
  • pyruvate carboxylase (PC)
  • pyruvate carboxylase (pyc)
  • pyruvate carboxylase Pyr1 (pyr1)
  • pyruvate carboxylase (CNF00650)
  • Pyruvate carboxylase (PYC1)
  • pyruvate carboxylase (Ndas_1152)
  • pyruvate carboxylase (Ilyop_2503)
  • pyruvate carboxylase (Calni_0495)
  • pyruvate carboxylase (Ftrac_1004)
  • pyruvate carboxylase (Plabr_3574)
  • pyruvate carboxylase (Sgly_2936)
  • pyruvate carboxylase (Celly_0558)
  • pyruvate carboxylase (Hipma_0131)
  • pyruvate carboxylase (Halhy_1567)
  • pyruvate carboxylase (Mesop_1269)
  • pyruvate carboxylase (Pcx)
  • pyruvate carboxylase (Pc)
  • BA4157
  • BcDNA
  • BcDNA:GH06348
  • Dmel\\CG1516
  • PC
  • Pc
  • Pcb
  • PCB
  • PCX
  • Pcx
  • pyc
  • wu:fb82g08
  • wu:fj85g01

Gene-IDs for different species

Protein level used designations for PC

  • CG1516-PA
  • CG1516-PB
  • CG1516-PD
  • CG1516-PE
  • CG1516-PG
  • CG1516-PI
  • CG1516-PJ
  • CG1516-PK
  • CG1516-PL
  • CG1516-PM
  • CG1516-PP
  • GH06348
  • pyruvate carboxykinase
  • pyruvate carboxylase
  • PYCb
  • pyruvate carboxylase, mitochondrial
  • PYruvate Carboxylase family member (pyc-1)
  • Pyruvate carboxylase
  • pyruvate decarboxylase
  • pyruvic carboxylase
  • PCB
Other products related to PC such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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