PHLPP2 (PH Domain and Leucine Rich Repeat Protein Phosphatase 2, PHLPP2)
Short Description: Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser- 657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Inhibits cancer cell proliferation and may act as a tumor suppressor.
More information related to gene PHLPP2.
More information related to gene PHLPP2.
Products related to PHLPP2 Gene:
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55 results
OriGene rc212846
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
- NCBI Accession:
- NM_015020,NP_055835
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5389488
$1,709.73
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc212846l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
- NCBI Accession:
- NM_015020,NP_055835
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5389492
$2,006.73
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
- NCBI Accession:
- NM_015020
- Gene ID:
- 23035 (Human, PHLPP2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4945480
$919.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 2 to 5 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
- NCBI Accession:
- NM_001289003
- Gene ID:
- 23035 (Human, PHLPP2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4945481
$919.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 2 to 5 Business Days
OriGene sr307954
RNAi
PHLPP2
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3283993
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to PHLPP2
- PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2)
- PH domain and leucine rich repeat protein phosphatase 2 S homeolog (phlpp2.S)
- PH domain and leucine rich repeat protein phosphatase 2 (phlpp2)
- PH domain and leucine rich repeat protein phosphatase 2 (Phlpp2)
- AI481772
- C130044A18Rik
- PHLPPL
- phlppl
- Phlppl
- RGD1562857
Gene-IDs for different species
Protein level used designations for PHLPP2
- PH domain leucine-rich repeat-containing protein phosphatase 2
- PH domain and leucine rich repeat protein phosphatase 2
- PH domain leucine-rich repeat-containing protein phosphatase 2-like
- GTPase activating protein and VPS9 domains 1
Proteomics products related to PHLPP2 Gene
Other products related to PHLPP2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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