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PHLPP2 (PH Domain and Leucine Rich Repeat Protein Phosphatase 2, PHLPP2)

Short Description: Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser- 657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Inhibits cancer cell proliferation and may act as a tumor suppressor.
More information related to gene PHLPP2.

Products related to PHLPP2 Gene:

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55 results

Human PHLPP2 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4420546
$1,108.18
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 32 Business Days
Details
Details
Rat PHLPP2 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_001109131
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4384011
$4,770.05
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 32 Business Days
Details
Details
Mouse PHLPP2 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_001122594
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4652004
$4,760.96
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 32 Business Days
Details
Details
Rat PHLPP2 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_001109131
Species:
Rat
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4666879
$4,770.05
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 32 Business Days
Details
Details
Human PHLPP2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4485632
$906.25
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 32 Business Days
Details
Details
Human PHLPP2 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4629103
$1,108.18
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 32 Business Days
Details
Details
Mouse PHLPP2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_001122594
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4452687
$4,559.04
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 32 Business Days
Details
Details
Rat PHLPP2 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
NCBI Accession:
NM_001109131
Species:
Rat
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4690575
$4,770.05
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 32 Business Days
Details
Details
Human PHLPP2 ORF Clone in Lenti Particles (GFP tag)
OriGene rc212846l2v ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN6412710
$2,254.23
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Details
Details
Human PHLPP2 ORF Clone in Lenti Particles (Myc-DYKDDDDK Tag)
OriGene rc212846l1v ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN6412709
$2,254.23
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • DYKDDDDK Tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pPB-His-GST
    • pPB-His-MBP
    • pRFP-C-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC-GFP
    • pDONR223
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PHLPP2

  • PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2)
  • PH domain and leucine rich repeat protein phosphatase 2 S homeolog (phlpp2.S)
  • PH domain and leucine rich repeat protein phosphatase 2 (phlpp2)
  • PH domain and leucine rich repeat protein phosphatase 2 (Phlpp2)
  • AI481772
  • C130044A18Rik
  • PHLPPL
  • phlppl
  • Phlppl
  • RGD1562857

Gene-IDs for different species

Protein level used designations for PHLPP2

  • PH domain leucine-rich repeat-containing protein phosphatase 2
  • PH domain and leucine rich repeat protein phosphatase 2
  • PH domain leucine-rich repeat-containing protein phosphatase 2-like
  • GTPase activating protein and VPS9 domains 1
Other products related to PHLPP2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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