PHLPP2 (PH Domain and Leucine Rich Repeat Protein Phosphatase 2, PHLPP2)
Short Description: Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser- 657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Inhibits cancer cell proliferation and may act as a tumor suppressor.
More information related to gene PHLPP2.
More information related to gene PHLPP2.
Products related to PHLPP2 Gene:
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55 results
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
- NCBI Accession:
- NM_001109131
- Species:
- Rat
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Catalog No. ABIN5736981
$3,526.25
Plus shipping costs $50.00
1 μg
Shipping to:
United States
Delivery in 11 to 22 Business Days
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
- NCBI Accession:
- NM_001122594
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Catalog No. ABIN5736980
$2,651.25
Plus shipping costs $50.00
1 μg
Shipping to:
United States
Delivery in 11 to 22 Business Days
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Catalog No. ABIN5736979
$551.25
Plus shipping costs $50.00
1 μg
Shipping to:
United States
Delivery in 11 to 22 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
- NCBI Accession:
- NM_001122594
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5227392
$857.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
- NCBI Accession:
- NM_001122594
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5227391
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
- NCBI Accession:
- NM_001109131
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5227394
$857.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
- NCBI Accession:
- NM_001109131
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5227393
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
- NCBI Accession:
- NM_015020
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5227390
$857.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
- NCBI Accession:
- NM_015020
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5227389
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2)
- NCBI Accession:
- NM_001122594
- Species:
- Mouse
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
Catalog No. ABIN4732354
$4,760.96
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 32 Business Days
Synonyms and alternative names related to PHLPP2
- PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2)
- PH domain and leucine rich repeat protein phosphatase 2 S homeolog (phlpp2.S)
- PH domain and leucine rich repeat protein phosphatase 2 (phlpp2)
- PH domain and leucine rich repeat protein phosphatase 2 (Phlpp2)
- AI481772
- C130044A18Rik
- PHLPPL
- phlppl
- Phlppl
- RGD1562857
Gene-IDs for different species
Protein level used designations for PHLPP2
- PH domain leucine-rich repeat-containing protein phosphatase 2
- PH domain and leucine rich repeat protein phosphatase 2
- PH domain leucine-rich repeat-containing protein phosphatase 2-like
- GTPase activating protein and VPS9 domains 1
Proteomics products related to PHLPP2 Gene
Other products related to PHLPP2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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