PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A, PPM1A)
Short Description: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
More information related to gene PPM1A.
More information related to gene PPM1A.
Products related to PPM1A Gene:
Recommended next Filters:
67 results
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Catalog No. ABIN5756883
$181.35
Plus shipping costs $50.00
1 μg
Shipping to:
United States
Delivery in 11 to 21 Business Days
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
Catalog No. ABIN4479690
$603.36
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 31 Business Days
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- NCBI Accession:
- NM_017038
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5150637
$693.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to:
United States
Delivery in 31 to 41 Business Days
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- NCBI Accession:
- NM_008910
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5150635
$693.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to:
United States
Delivery in 31 to 41 Business Days
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- NCBI Accession:
- NM_177952
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5150633
$693.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to:
United States
Delivery in 31 to 41 Business Days
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
Catalog No. ABIN4837979
$805.29
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 31 Business Days
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
Catalog No. ABIN4708849
$805.29
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 31 Business Days
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-His
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- His tag
- Expression:
- Stable, Transient
Catalog No. ABIN4414605
$805.29
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 31 Business Days
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
Catalog No. ABIN4623161
$805.29
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 31 Business Days
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- NCBI Accession:
- NM_008910
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Catalog No. ABIN5756884
$813.75
Plus shipping costs $50.00
1 μg
Shipping to:
United States
Delivery in 11 to 21 Business Days
Synonyms and alternative names related to PPM1A
- protein phosphatase, Mg2+/Mn2+ dependent 1A (PPM1A)
- protein phosphatase, Mg2+/Mn2+ dependent, 1Ab (ppm1ab)
- protein phosphatase 1A, magnesium dependent, alpha isoform (Ppm1a)
- protein phosphatase, Mg2+/Mn2+ dependent, 1A (Ppm1a)
- protein phosphatase, Mg2+/Mn2+ dependent 1A L homeolog (ppm1a.L)
- protein phosphatase, Mg2+/Mn2+ dependent 1A (Ppm1a)
- protein phosphatase, Mg2+/Mn2+ dependent, 1Aa (ppm1aa)
- 2310003C21Rik
- 2900017D14Rik
- AI427932
- AU017636
- MMPa-2
- MPPa-1
- PP2C-ALPHA
- pp2c-alpha
- Pp2c1
- PP2CA
- pp2ca
- pp2ca1
- pp2ca2
- PP2Calpha
- pp2calpha
- ppp1r13b
- si:ch211-253p18.1
- wu:fd42g12
- zgc:153820
Gene-IDs for different species
Protein level used designations for PPM1A
- protein phosphatase 1A
- protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform
- protein phosphatase type 2C alpha 1
- protein phosphatase 1, regulatory (inhibitor) subunit 13B
- Mpp alpha
- PP2C-alpha
- protein phosphatase 2C isoform alpha
- protein phosphatase IA
- IA
- Protein phosphatase type 1A (formely 2C) Mg-dependent alpha isoform
- Protein phosphatase type 1A (formely 2C), Mg-dependent, alpha isoform
- protein phosphatase 1A, magnesium dependent, alpha isoform
- protein phosphatase 2C alpha
- protein phosphatase type 2C alpha 2
Proteomics products related to PPM1A Gene
Other products related to PPM1A such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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