PSMA (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1, FOLH1)
Short Description: This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010].
More information related to gene PSMA.
More information related to gene PSMA.
Products related to PSMA Gene:
Recommended next Filters:
79 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1)
- NCBI Accession:
- NM_004476
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1)
- NCBI Accession:
- NM_004476
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1)
- NCBI Accession:
- NM_016770
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1)
- NCBI Accession:
- NM_016770
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1)
- NCBI Accession:
- NM_057185
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1)
- NCBI Accession:
- NM_001014986
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1)
- NCBI Accession:
- NM_057185
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1)
- NCBI Accession:
- NM_016770
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1)
- NCBI Accession:
- NM_001014986
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1)
- NCBI Accession:
- NM_016770
- Species:
- Mouse
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
Synonyms and alternative names related to PSMA
- putative N-acetylated-alpha-linked acidic dipeptidase (LOC451185)
- folate hydrolase 1B (FOLH1B)
- folate hydrolase 1 (FOLH1)
- folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1)
- folate hydrolase 1 (Folh1)
- FGCP
- FOLH
- GCP2
- GCPII
- mGCP
- mopsm
- Naalad
- NAALAD1
- NAALAdase
- PSM
- PSMA
Gene-IDs for different species
Protein level used designations for PSMA
- folate hydrolase 1
- glutamate carboxypeptidase 2
- folate hydrolase (prostate-specific membrane antigen) 1
- glutamate carboxypeptidase 2-like
- N-acetylated alpha-linked acidic dipeptidase 1
- N-acetylated-alpha-linked acidic dipeptidase I
- NAALADase I
- cell growth-inhibiting gene 27 protein
- folylpoly-gamma-glutamate carboxypeptidase
- glutamate carboxylase II
- glutamate carboxypeptidase II
- membrane glutamate carboxypeptidase
- prostate specific membrane antigen variant F
- pteroylpoly-gamma-glutamate carboxypeptidase
- FGCP
- GCPII
- mGCP
- prostate-specific membrane antigen homolog
- prostate-specific membrane antigen
- N-acetylated alpha-linked acidic dipeptidase
Proteomics products related to PSMA Gene
Other products related to PSMA such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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