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SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit, SCN1A)

Short Description: The vertebrate sodium channel is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and two smaller auxiliary beta subunits. This gene encodes the large alpha subunit, and mutations in this gene have been associated with several epilepsy, convulsion and migraine disorders. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript.[provided by RefSeq, Jan 2011].
More information related to gene SCN1A.

Products related to SCN1A Gene:

50 results :

Rat SCN1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_030875
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5238051
Datasheet
Catalog No. ABIN5238051
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_030875
Species:
Rat
Synonyms:
SCN1A, SCN9A, Scn1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Scn1a
Format:
Viral Particles
Storage:
-80 °C
Human SCN1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_006920
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5238047
Datasheet
Catalog No. ABIN5238047
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_006920
Species:
Human
Synonyms:
SCN1A, SCN9A, Scn1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SCN1A
Format:
Viral Particles
Storage:
-80 °C
Mouse SCN1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_018733
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5238049
Datasheet
Catalog No. ABIN5238049
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_018733
Species:
Mouse
Synonyms:
SCN1A, SCN9A, Scn1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Scn1a
Format:
Viral Particles
Storage:
-80 °C
Mouse SCN1A cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_018733
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4455485
Datasheet
Catalog No. ABIN4455485
Type:
cDNA
Application:
Protein Expression
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_018733
Species:
Mouse
Synonyms:
SCN1A, SCN9A, Scn1a
Insert length:
5997 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat SCN1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_030875
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5122672
Datasheet
Catalog No. ABIN5122672
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_030875
Species:
Rat
Synonyms:
SCN1A, SCN9A, Scn1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Scn1a
Format:
Viral Particles
Storage:
-80 °C
Mouse SCN1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_018733
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5122670
Datasheet
Catalog No. ABIN5122670
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_018733
Species:
Mouse
Synonyms:
SCN1A, SCN9A, Scn1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Scn1a
Format:
Viral Particles
Storage:
-80 °C
Human SCN1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_006920
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5122668
Datasheet
Catalog No. ABIN5122668
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_006920
Species:
Human
Synonyms:
SCN1A, SCN9A, Scn1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SCN1A
Format:
Viral Particles
Storage:
-80 °C
Mouse SCN1A cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_018733
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4864283
Datasheet
Catalog No. ABIN4864283
Type:
cDNA
Application:
Cloning
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_018733
Species:
Mouse
Synonyms:
SCN1A, SCN9A, Scn1a
Insert length:
8287 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse SCN1A cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_018733
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4654802
Datasheet
Catalog No. ABIN4654802
Type:
cDNA
Application:
Cloning
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_018733
Species:
Mouse
Synonyms:
SCN1A, SCN9A, Scn1a
Insert length:
5997 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse SCN1A cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_018733
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4735152
Datasheet
Catalog No. ABIN4735152
Type:
cDNA
Application:
Cloning
Gene:
Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A)
NCBI Accession:
NM_018733
Species:
Mouse
Synonyms:
SCN1A, SCN9A, Scn1a
Insert length:
8287 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC-Myc-DDK
    • pCMV6-Entry
    • pCMV6-XL5
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • ORF
    • cDNA
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to SCN1A

  • sodium voltage-gated channel alpha subunit 1 (SCN1A)
  • sodium voltage-gated channel alpha subunit 9 (SCN9A)
  • sodium channel, voltage-gated, type I, alpha (Scn1a)
  • sodium voltage-gated channel alpha subunit 1 (Scn1a)
  • B230332M13
  • EIEE6
  • FEB3
  • FEB3A
  • FHM3
  • GEFSP2
  • HBSCI
  • NAC1
  • Nav1.1
  • SCN1
  • SCN1A
  • SCN9A
  • SMEI

Gene-IDs for different species

Protein level used designations for SCN1A

  • sodium channel, voltage-gated, type IX, alpha subunit
  • voltage-gated sodium channel I
  • sodium channel, voltage-gated, type I, alpha subunit
  • sodium channel protein brain I subunit alpha
  • sodium channel protein type 1 subunit alpha
  • sodium channel protein type I subunit alpha
  • sodium channel protein, brain I subunit alpha
  • sodium channel voltage-gated type I alpha polypeptide
  • sodium channel, voltage-gated, type 1, alpha polypeptide
  • sodium channel, voltage-gated, type I, alpha polypeptide
  • voltage-gated sodium channel subunit alpha Nav1.1
  • sodium channel protein, brain I alpha subunit
  • sodium channel voltage gated type 1 alpha subunit
  • sodium channel voltage-gated type I alpha
Other products related to SCN1A such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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