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SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2, SHANK2)

Short Description: This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].
More information related to gene SHANK2.

Products related to SHANK2 Gene:

78 results :

Rat SHANK2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_133440
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5097708
Datasheet
Catalog No. ABIN5097708
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_133440
Species:
Rat
Synonyms:
SHANK2, Shank2, shank2.L, shank2, LOC100438523
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Shank2
Format:
Viral Particles
Storage:
-80 °C
Mouse SHANK2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_001113373
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5097706
Datasheet
Catalog No. ABIN5097706
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_001113373
Species:
Mouse
Synonyms:
SHANK2, Shank2, shank2.L, shank2, LOC100438523
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Shank2
Format:
Viral Particles
Storage:
-80 °C
Human SHANK2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_012309
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5097704
Datasheet
Catalog No. ABIN5097704
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_012309
Species:
Human
Synonyms:
SHANK2, Shank2, shank2.L, shank2, LOC100438523
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SHANK2
Format:
Viral Particles
Storage:
-80 °C
Mouse SHANK2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_001081370
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5729209
Datasheet
Catalog No. ABIN5729209
Type:
ORF
Application:
Cloning
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_001081370
Species:
Mouse
Synonyms:
SHANK2, Shank2, shank2.L, shank2, LOC100438523
Insert length:
3789 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat SHANK2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_133440
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5729211
Datasheet
Catalog No. ABIN5729211
Type:
ORF
Application:
Cloning
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_133440
Species:
Rat
Synonyms:
SHANK2, Shank2, shank2.L, shank2, LOC100438523
Insert length:
3780 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat SHANK2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_133440
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5212946
Datasheet
Catalog No. ABIN5212946
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_133440
Species:
Rat
Synonyms:
SHANK2, Shank2, shank2.L, shank2, LOC100438523
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Shank2
Format:
Viral Particles
Storage:
-80 °C
Mouse SHANK2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_001113373
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5212944
Datasheet
Catalog No. ABIN5212944
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_001113373
Species:
Mouse
Synonyms:
SHANK2, Shank2, shank2.L, shank2, LOC100438523
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Shank2
Format:
Viral Particles
Storage:
-80 °C
Human SHANK2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_012309
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5212942
Datasheet
Catalog No. ABIN5212942
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_012309
Species:
Human
Synonyms:
SHANK2, Shank2, shank2.L, shank2, LOC100438523
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SHANK2
Format:
Viral Particles
Storage:
-80 °C
Human SHANK2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_012309
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4490281
Datasheet
Catalog No. ABIN4490281
Type:
cDNA
Application:
Protein Expression
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_012309
Species:
Human
Synonyms:
SHANK2, Shank2, shank2.L, shank2, LOC100438523
Insert length:
846 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SHANK2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_012309
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5729208
Datasheet
Catalog No. ABIN5729208
Type:
ORF
Application:
Cloning
Gene:
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2)
NCBI Accession:
NM_012309
Species:
Human
Synonyms:
SHANK2, Shank2, shank2.L, shank2, LOC100438523
Insert length:
5550 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Rat
    • Human
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • His tag
    • GFP tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL5
  • Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Lentiviral Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SHANK2

  • SH3 and multiple ankyrin repeat domains 2 (SHANK2)
  • SH3 and multiple ankyrin repeat domains 2 (Shank2)
  • SH3 and multiple ankyrin repeat domains 2 L homeolog (shank2.L)
  • SH3 and multiple ankyrin repeat domains 2 (shank2)
  • SH3 and multiple ankyrin repeat domains protein 2 (LOC100438523)
  • AUTS17
  • auts17
  • CORTBP1
  • cortbp1
  • CortBP1
  • CTTNBP1
  • cttnbp1
  • MGC122482
  • mKIAA1022
  • ProSAP1
  • prosap1
  • SHANK
  • shank2
  • SHANK2
  • SPANK-3
  • spank-3
  • Spank-3

Gene-IDs for different species

Protein level used designations for SHANK2

  • GKAP/SAPAP interacting protein
  • SH3 and multiple ankyrin repeat domains protein 2
  • cortactin SH3 domain-binding protein
  • cortactin-binding protein 1
  • proline-rich synapse associated protein 1
  • proline-rich synapse-associated protein 1
  • cortBP1
  • SH3 and multiple ankyrin repeat domains 2
  • SH3/ankyrin domain gene 2
  • SH3 and multiple ankyrin repeat domains protein 2-like
  • GKAP/SAPAP-interacting protein
  • proline rich synapse associated protein 1
Other products related to SHANK2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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