SMAD2 (SMAD, Mothers Against DPP Homolog 2, SMAD2)
Short Description: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012].
More information related to gene SMAD2.
More information related to gene SMAD2.
Products related to SMAD2 Gene:
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76 results
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_010754
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Catalog No. ABIN5728120
$813.75
Plus shipping costs $50.00
1 μg
Shipping to:
United States
Delivery in 11 to 22 Business Days
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_005901
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Catalog No. ABIN5728119
$181.35
Plus shipping costs $50.00
1 μg
Shipping to:
United States
Delivery in 11 to 22 Business Days
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_001252481
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Catalog No. ABIN5728121
$4,223.91
Plus shipping costs $50.00
1 μg
Shipping to:
United States
Delivery in 11 to 22 Business Days
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_019191
- Species:
- Rat
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Catalog No. ABIN5728122
$813.75
Plus shipping costs $50.00
1 μg
Shipping to:
United States
Delivery in 11 to 22 Business Days
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_001252481
- Species:
- Mouse
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
Catalog No. ABIN4736321
$9,602.06
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 32 Business Days
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_010754
- Species:
- Mouse
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
Catalog No. ABIN4736320
$1,441.35
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 32 Business Days
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_019191
- Species:
- Rat
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
Catalog No. ABIN4755035
$1,441.35
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 32 Business Days
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_005901
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
Catalog No. ABIN4840522
$805.29
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 32 Business Days
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_005901
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
Catalog No. ABIN4711391
$805.29
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 32 Business Days
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_019191
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5095628
$693.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to:
United States
Delivery in 31 to 42 Business Days
Synonyms and alternative names related to SMAD2
- SMAD family member 2 (SMAD2)
- SMAD family member 2-Z (SMAD2Z)
- SMAD family member 2 (smad2)
- SMAD family member 2 S homeolog (smad2.S)
- SMAD family member 2 (Smad2)
- 7120426M23Rik
- fj43c06
- hMAD-2
- hmad-2
- hSMAD2
- hsmad2
- JV18
- jv18
- JV18-1
- jv18-1
- MADH2
- madh2
- Madh2
- MAD homolog 2
- MADR2
- madr2
- Madr2
- mMad2
- Mothers against DPP homolog 2
- smad-2
- Smad-2
- SMAD 2
- Smad2
- wu:fj43c06
- Xmad2
- XSmad2
Gene-IDs for different species
Protein level used designations for SMAD2
- MAD homolog 2
- SMAD, mothers against DPP homolog 2
- Sma- and Mad-related protein 2
- mother against DPP homolog 2
- mothers against decapentaplegic homolog 2
- SMAD 2
- mothers against DPP homolog 2
- mothers against decapentaplegic-like 2
- MAD (mothers against decapentaplegic, Drosophila) homolog 2
- SMA- and MAD-related protein 2
- SMAD family member 2
- Smad 2
- mad-related protein 2
- LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 2
Proteomics products related to SMAD2 Gene
Other products related to SMAD2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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