SMAD2 (SMAD, Mothers Against DPP Homolog 2, SMAD2)
Short Description: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012].
More information related to gene SMAD2.
More information related to gene SMAD2.
Products related to SMAD2 Gene:
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OriGene rc204604l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_005901,NP_005892
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5361191
$749.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc206526l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_001003652,NP_001003652
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5361192
$749.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc226623l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_001135937,NP_001129409
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5361193
$749.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc226623l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_001135937,NP_001129409
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5361197
$749.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_001135937
- Gene ID:
- 4087 (Human, SMAD2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4923348
$319.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 9 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_001003652
- Gene ID:
- 4087 (Human, SMAD2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4918065
$319.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
Synonyms and alternative names related to SMAD2
- SMAD family member 2 (SMAD2)
- SMAD family member 2-Z (SMAD2Z)
- SMAD family member 2 (smad2)
- SMAD family member 2 S homeolog (smad2.S)
- SMAD family member 2 (Smad2)
- 7120426M23Rik
- fj43c06
- hMAD-2
- hmad-2
- hSMAD2
- hsmad2
- JV18
- jv18
- JV18-1
- jv18-1
- MADH2
- madh2
- Madh2
- MAD homolog 2
- MADR2
- madr2
- Madr2
- mMad2
- Mothers against DPP homolog 2
- smad-2
- Smad-2
- SMAD 2
- Smad2
- wu:fj43c06
- Xmad2
- XSmad2
Gene-IDs for different species
Protein level used designations for SMAD2
- MAD homolog 2
- SMAD, mothers against DPP homolog 2
- Sma- and Mad-related protein 2
- mother against DPP homolog 2
- mothers against decapentaplegic homolog 2
- SMAD 2
- mothers against DPP homolog 2
- mothers against decapentaplegic-like 2
- MAD (mothers against decapentaplegic, Drosophila) homolog 2
- SMA- and MAD-related protein 2
- SMAD family member 2
- Smad 2
- mad-related protein 2
- LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 2
Proteomics products related to SMAD2 Gene
Other products related to SMAD2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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