SMAD2 (SMAD, Mothers Against DPP Homolog 2, SMAD2)
Short Description: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012].
More information related to gene SMAD2.
More information related to gene SMAD2.
Products related to SMAD2 Gene:
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76 results
OriGene sr415158
RNAi
SMAD2
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- SMAD, Mothers Against DPP Homolog 2
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3271222
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene sc321776
cDNA
PExp
Mammalian Expression Vector
pCMV6-AC
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_001003652,NP_001003652
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3319345
$452.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene sr512205
RNAi
SMAD2
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- SMAD, Mothers Against DPP Homolog 2
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3361013
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene kn516271
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3223822
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn404604
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3223821
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc325924
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_001135937,NP_001129409
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3322773
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rn212493
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_019191,NP_062064
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3371179
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rn216735
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_001277450,NP_001264379
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3371180
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene mc227845
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_001252481,NP_001239410
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3371178
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sc116434
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- SMAD, Mothers Against DPP Homolog 2 (SMAD2)
- NCBI Accession:
- NM_005901,NP_005892
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3386827
$452.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to SMAD2
- SMAD family member 2 (SMAD2)
- SMAD family member 2-Z (SMAD2Z)
- SMAD family member 2 (smad2)
- SMAD family member 2 S homeolog (smad2.S)
- SMAD family member 2 (Smad2)
- 7120426M23Rik
- fj43c06
- hMAD-2
- hmad-2
- hSMAD2
- hsmad2
- JV18
- jv18
- JV18-1
- jv18-1
- MADH2
- madh2
- Madh2
- MAD homolog 2
- MADR2
- madr2
- Madr2
- mMad2
- Mothers against DPP homolog 2
- smad-2
- Smad-2
- SMAD 2
- Smad2
- wu:fj43c06
- Xmad2
- XSmad2
Gene-IDs for different species
Protein level used designations for SMAD2
- MAD homolog 2
- SMAD, mothers against DPP homolog 2
- Sma- and Mad-related protein 2
- mother against DPP homolog 2
- mothers against decapentaplegic homolog 2
- SMAD 2
- mothers against DPP homolog 2
- mothers against decapentaplegic-like 2
- MAD (mothers against decapentaplegic, Drosophila) homolog 2
- SMA- and MAD-related protein 2
- SMAD family member 2
- Smad 2
- mad-related protein 2
- LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 2
Proteomics products related to SMAD2 Gene
Other products related to SMAD2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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