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Topoisomerase I (Topoisomerase (DNA) I, TOP1)

Short Description: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008].
More information related to gene Topoisomerase I.

Products related to Topoisomerase I Gene:

55 results :

Human TOP1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Topoisomerase (DNA) I (TOP1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4842198
Datasheet
Catalog No. ABIN4842198
Type:
cDNA
Application:
Cloning
Gene:
Topoisomerase (DNA) I (TOP1)
Species:
Human
Synonyms:
Top1, top1, topA, ZMO1193, MRAD2831_RS63095, Lferr_0016, PC1_2015, Za10_0136, Gbro_0575, Dd586_2108, Kvar_3044, Alvin_2069, Dacet_0849, Mrub_1615, Arnit_2962, Ndas_4953, Trad_2377, Acear_1653, Mahau_0844, Mesop_4109, Thein_1586, Theth_0241, TOP1ALPHA, top-1, TOP1, top1.1.L
Insert length:
2298 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human TOP1 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Topoisomerase (DNA) I (TOP1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4713067
Datasheet
Catalog No. ABIN4713067
Type:
cDNA
Application:
Cloning
Gene:
Topoisomerase (DNA) I (TOP1)
Species:
Human
Synonyms:
Top1, top1, topA, ZMO1193, MRAD2831_RS63095, Lferr_0016, PC1_2015, Za10_0136, Gbro_0575, Dd586_2108, Kvar_3044, Alvin_2069, Dacet_0849, Mrub_1615, Arnit_2962, Ndas_4953, Trad_2377, Acear_1653, Mahau_0844, Mesop_4109, Thein_1586, Theth_0241, TOP1ALPHA, top-1, TOP1, top1.1.L
Insert length:
2298 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human TOP1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Topoisomerase (DNA) I (TOP1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5722969
Datasheet
Catalog No. ABIN5722969
Type:
ORF
Application:
Cloning
Gene:
Topoisomerase (DNA) I (TOP1)
Species:
Human
Synonyms:
Top1, top1, topA, ZMO1193, MRAD2831_RS63095, Lferr_0016, PC1_2015, Za10_0136, Gbro_0575, Dd586_2108, Kvar_3044, Alvin_2069, Dacet_0849, Mrub_1615, Arnit_2962, Ndas_4953, Trad_2377, Acear_1653, Mahau_0844, Mesop_4109, Thein_1586, Theth_0241, TOP1ALPHA, top-1, TOP1, top1.1.L
Insert length:
2298 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat TOP1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Topoisomerase (DNA) I (TOP1)
NCBI Accession:
NM_022615
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5087248
Datasheet
Catalog No. ABIN5087248
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Topoisomerase (DNA) I (TOP1)
NCBI Accession:
NM_022615
Species:
Rat
Synonyms:
Top1, top1, topA, ZMO1193, MRAD2831_RS63095, Lferr_0016, PC1_2015, Za10_0136, Gbro_0575, Dd586_2108, Kvar_3044, Alvin_2069, Dacet_0849, Mrub_1615, Arnit_2962, Ndas_4953, Trad_2377, Acear_1653, Mahau_0844, Mesop_4109, Thein_1586, Theth_0241, TOP1ALPHA, top-1, TOP1, top1.1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Top1
Format:
Viral Particles
Storage:
-80 °C
Mouse TOP1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Topoisomerase (DNA) I (TOP1)
NCBI Accession:
NM_009408
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5087246
Datasheet
Catalog No. ABIN5087246
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Topoisomerase (DNA) I (TOP1)
NCBI Accession:
NM_009408
Species:
Mouse
Synonyms:
Top1, top1, topA, ZMO1193, MRAD2831_RS63095, Lferr_0016, PC1_2015, Za10_0136, Gbro_0575, Dd586_2108, Kvar_3044, Alvin_2069, Dacet_0849, Mrub_1615, Arnit_2962, Ndas_4953, Trad_2377, Acear_1653, Mahau_0844, Mesop_4109, Thein_1586, Theth_0241, TOP1ALPHA, top-1, TOP1, top1.1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Top1
Format:
Viral Particles
Storage:
-80 °C
Human TOP1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Topoisomerase (DNA) I (TOP1)
NCBI Accession:
NM_003286
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5087244
Datasheet
Catalog No. ABIN5087244
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Topoisomerase (DNA) I (TOP1)
NCBI Accession:
NM_003286
Species:
Human
Synonyms:
Top1, top1, topA, ZMO1193, MRAD2831_RS63095, Lferr_0016, PC1_2015, Za10_0136, Gbro_0575, Dd586_2108, Kvar_3044, Alvin_2069, Dacet_0849, Mrub_1615, Arnit_2962, Ndas_4953, Trad_2377, Acear_1653, Mahau_0844, Mesop_4109, Thein_1586, Theth_0241, TOP1ALPHA, top-1, TOP1, top1.1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of TOP1
Format:
Viral Particles
Storage:
-80 °C
Mouse TOP1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Topoisomerase (DNA) I (TOP1)
NCBI Accession:
NM_009408
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5722970
Datasheet
Catalog No. ABIN5722970
Type:
ORF
Application:
Cloning
Gene:
Topoisomerase (DNA) I (TOP1)
NCBI Accession:
NM_009408
Species:
Mouse
Synonyms:
Top1, top1, topA, ZMO1193, MRAD2831_RS63095, Lferr_0016, PC1_2015, Za10_0136, Gbro_0575, Dd586_2108, Kvar_3044, Alvin_2069, Dacet_0849, Mrub_1615, Arnit_2962, Ndas_4953, Trad_2377, Acear_1653, Mahau_0844, Mesop_4109, Thein_1586, Theth_0241, TOP1ALPHA, top-1, TOP1, top1.1.L
Insert length:
2304 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat TOP1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Topoisomerase (DNA) I (TOP1)
NCBI Accession:
NM_022615
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5722971
Datasheet
Catalog No. ABIN5722971
Type:
ORF
Application:
Cloning
Gene:
Topoisomerase (DNA) I (TOP1)
NCBI Accession:
NM_022615
Species:
Rat
Synonyms:
Top1, top1, topA, ZMO1193, MRAD2831_RS63095, Lferr_0016, PC1_2015, Za10_0136, Gbro_0575, Dd586_2108, Kvar_3044, Alvin_2069, Dacet_0849, Mrub_1615, Arnit_2962, Ndas_4953, Trad_2377, Acear_1653, Mahau_0844, Mesop_4109, Thein_1586, Theth_0241, TOP1ALPHA, top-1, TOP1, top1.1.L
Insert length:
2304 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat TOP1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Topoisomerase (DNA) I (TOP1)
NCBI Accession:
NM_022615
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5202390
Datasheet
Catalog No. ABIN5202390
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Topoisomerase (DNA) I (TOP1)
NCBI Accession:
NM_022615
Species:
Rat
Synonyms:
Top1, top1, topA, ZMO1193, MRAD2831_RS63095, Lferr_0016, PC1_2015, Za10_0136, Gbro_0575, Dd586_2108, Kvar_3044, Alvin_2069, Dacet_0849, Mrub_1615, Arnit_2962, Ndas_4953, Trad_2377, Acear_1653, Mahau_0844, Mesop_4109, Thein_1586, Theth_0241, TOP1ALPHA, top-1, TOP1, top1.1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Top1
Format:
Viral Particles
Storage:
-80 °C
Mouse TOP1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Topoisomerase (DNA) I (TOP1)
NCBI Accession:
NM_009408
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5202388
Datasheet
Catalog No. ABIN5202388
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Topoisomerase (DNA) I (TOP1)
NCBI Accession:
NM_009408
Species:
Mouse
Synonyms:
Top1, top1, topA, ZMO1193, MRAD2831_RS63095, Lferr_0016, PC1_2015, Za10_0136, Gbro_0575, Dd586_2108, Kvar_3044, Alvin_2069, Dacet_0849, Mrub_1615, Arnit_2962, Ndas_4953, Trad_2377, Acear_1653, Mahau_0844, Mesop_4109, Thein_1586, Theth_0241, TOP1ALPHA, top-1, TOP1, top1.1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Top1
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • ORF
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to Topoisomerase I

  • Topoisomerase 1 (Top1)
  • DNA topoisomerase I (top1)
  • DNA topoisomerase I (topA)
  • DNA topoisomerase I (ZMO1193)
  • DNA topoisomerase I (MRAD2831_RS63095)
  • DNA topoisomerase I (Lferr_0016)
  • DNA topoisomerase I (PC1_2015)
  • DNA topoisomerase I (Za10_0136)
  • DNA topoisomerase I (Gbro_0575)
  • DNA topoisomerase I (Dd586_2108)
  • DNA topoisomerase I (Kvar_3044)
  • DNA topoisomerase I (Alvin_2069)
  • DNA topoisomerase I (Dacet_0849)
  • DNA topoisomerase I (Mrub_1615)
  • DNA topoisomerase I (Arnit_2962)
  • DNA topoisomerase I (Ndas_4953)
  • DNA topoisomerase I (Trad_2377)
  • DNA topoisomerase I (Acear_1653)
  • DNA topoisomerase I (Mahau_0844)
  • DNA topoisomerase I (Mesop_4109)
  • DNA topoisomerase I (Thein_1586)
  • DNA topoisomerase I (Theth_0241)
  • DNA topoisomerase I alpha (TOP1ALPHA)
  • DNA topoisomerase 1 (top-1)
  • DNA topoisomerase I (TOP1)
  • topoisomerase (DNA) I (Top1)
  • DNA topoisomerase I (Top1)
  • DNA topoisomerase I, gene 1 L homeolog (top1.1.L)
  • Ab2-086
  • AI467334
  • CG6146
  • D130064I21Rik
  • Dmel\\CG6146
  • DNA topoisomerase 1 beta
  • DNA topoisomerase I alpha
  • dTopoI
  • l(1)G0134
  • l(1)G0201
  • l(1)G0229
  • l(1)G0278
  • l(1)top1
  • MGO1
  • MGOUN 1
  • MTE17.1
  • MTE17_1
  • Top-1
  • TOP1
  • top1
  • TOP1BETA
  • TopI
  • TOPI
  • topi
  • Topo I
  • TopoI
  • topo I
  • topoI
  • TOPOISOMERASE 1

Gene-IDs for different species

Protein level used designations for Topoisomerase I

  • CG6146-PA
  • CG6146-PB
  • CG6146-PC
  • CG6146-PD
  • Top1-PA
  • Top1-PB
  • Top1-PC
  • Top1-PD
  • topoisomerase 1
  • topoisomerase I
  • topoisomerase1
  • type I topoisomerase
  • DNA topoisomerase I
  • DNA topoisomerase 1
  • type I DNA topoisomerase
Other products related to Topoisomerase I such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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