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ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase, ABL1)

Short Description: The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9\;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq, Jul 2008].
More information related to gene ABL1.

Products related to ABL1 Gene:

71 results :

Human ABL1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_007313
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5746582
Datasheet
Catalog No. ABIN5746582
Type:
ORF
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_007313
Species:
Human
Synonyms:
ABL1, Abl1, abl-1, abl1
Insert length:
3450 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat ABL1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_001100850
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5245601
Datasheet
Catalog No. ABIN5245601
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_001100850
Species:
Rat
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abl1
Format:
Viral Particles
Storage:
-80 °C
Mouse ABL1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_009594
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5245599
Datasheet
Catalog No. ABIN5245599
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_009594
Species:
Mouse
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abl1
Format:
Viral Particles
Storage:
-80 °C
Human ABL1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_005157
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5245597
Datasheet
Catalog No. ABIN5245597
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_005157
Species:
Human
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABL1
Format:
Viral Particles
Storage:
-80 °C
Rat ABL1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_001100850
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5130166
Datasheet
Catalog No. ABIN5130166
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_001100850
Species:
Rat
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abl1
Format:
Viral Particles
Storage:
-80 °C
Mouse ABL1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_009594
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5130164
Datasheet
Catalog No. ABIN5130164
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_009594
Species:
Mouse
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abl1
Format:
Viral Particles
Storage:
-80 °C
Human ABL1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_005157
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5130162
Datasheet
Catalog No. ABIN5130162
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_005157
Species:
Human
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABL1
Format:
Viral Particles
Storage:
-80 °C
Mouse ABL1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_009594
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5746583
Datasheet
Catalog No. ABIN5746583
Type:
ORF
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_009594
Species:
Mouse
Synonyms:
ABL1, Abl1, abl-1, abl1
Insert length:
3372 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse ABL1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_001112703
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5746584
Datasheet
Catalog No. ABIN5746584
Type:
ORF
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_001112703
Species:
Mouse
Synonyms:
ABL1, Abl1, abl-1, abl1
Insert length:
3429 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat ABL1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_001100850
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5746585
Datasheet
Catalog No. ABIN5746585
Type:
ORF
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_001100850
Species:
Rat
Synonyms:
ABL1, Abl1, abl-1, abl1
Insert length:
3432 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRFP-C-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to ABL1

  • ABL proto-oncogene 1, non-receptor tyrosine kinase (ABL1)
  • c-abl oncogene 1, non-receptor tyrosine kinase (Abl1)
  • ABL proto-oncogene 1, non-receptor tyrosine kinase (Abl1)
  • Tyrosine-protein kinase abl-1 (abl-1)
  • c-abl oncogene 1, non-receptor tyrosine kinase (abl1)
  • ABL
  • Abl
  • AI325092
  • bcr/abl
  • c-ABL
  • c-Abl
  • E430008G22Rik
  • JTK7
  • p150
  • v-abl

Gene-IDs for different species

Protein level used designations for ABL1

  • Abelson tyrosine-protein kinase 1
  • bcr/c-abl oncogene protein
  • c-abl oncogene 1, receptor tyrosine kinase
  • proto-oncogene c-Abl
  • proto-oncogene tyrosine-protein kinase ABL1
  • tyrosine-protein kinase ABL1
  • v-abl Abelson murine leukemia viral oncogene homolog 1
  • Abelson murine leukemia oncogene
  • abelson murine leukemia viral oncogene homolog 1
  • p150
  • v-abl Abelson murine leukemia oncogene 1
  • Abelson murine leukemia viral (v-abl) oncogene homolog 1
  • v-abl Abelson murine leukemia viral oncogene 1
Other products related to ABL1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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