ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase, ABL1)

Short Description: The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9\;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq, Jul 2008].
More information related to gene ABL1.
Products related to ABL1 Gene:
126 Products
Data Quality
  • 2
Type
  • 122
  • 4
Species
  • 58
  • 52
  • 16
Application
  • 78
  • 26
  • 19
  • 16
  • 1
Fusion tag
  • 38
  • 18
  • 14
  • 14
  • 8
Vector Backbone
  • 10
  • 10
  • 9
  • 6
  • 6
Vector
  • 50
  • 42
  • 16
  • 6
  • 6
Insert
  • 46
  • 44
  • 16
  • 8
  • 6
Oligo-Type
  • 3
  • 1
Resistance Gene
  • 57
  • 36
  • 24
  • 5
  • 2
Expression Type
  • 105
  • 50
  • 13
Selectable Marker
  • 37
  • 22
  • 13
Promoter
  • 44
  • 26
  • 26
  • 18
  • 8
Format
  • 56
  • 36
  • 26
  • 8
Supplier: Log in to see

Full length Mus musculus c-abl oncogene 1, non-receptor tyrosine kinase cDNA clone.

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
Gene ID:
11350 (Mouse (Murine), ABL1)
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Mammalian Expression Vector
Vector backbone:
pExpress-1
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN4045141
$110.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
Supplier: Log in to see

Full length Homo sapiens c-abl oncogene 1, non-receptor tyrosine kinase cDNA clone.

Type:
cDNA
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
Gene ID:
25 (Human, ABL1)
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Cloning Vector
Vector backbone:
pCR4-TOPO
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin

Sequencing Primer:
  • T7
  • T3
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3998308
$110.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
Supplier: Log in to see

Full length Clone DNA of Homo sapiens c-abl oncogene 1, receptor tyrosine kinase.

Type:
cDNA
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
BC_117451
Species:
Human
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
TA-Cloning Vector
Vector backbone:
pMD18-T Simple
Resistance Gene:
Ampicillin

Sequencing Primer:
  • M13-47 and RV-M
Format:
Lyophilized
Storage:
RT
Catalog No. ABIN3610999
$125.00
1 vial
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
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Verified forward and reverse primers for analyzing the quantitative expression of gene

Application:
Quantitative real-time PCR
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase
Species:
Human
Synonyms:
ABL, JTK7, bcr/abl, c-ABL, p150, v-abl, AI325092, Abl, E430008G22Rik, c-Abl
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3189439
$129.00
1 vial
Plus shipping costs $45.00
Delivery in 15 to 19 Business Days
Supplier: Log in to see

Full length, sequence guaranteed Mus musculus c-abl oncogene 1, non-receptor tyrosine kinase cDNA clone.

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
Gene ID:
11350 (Mouse (Murine), ABL1)
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Mammalian Expression Vector
Vector backbone:
pExpress-1
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN4045142
$154.44
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
Supplier: Log in to see

Full length, sequence guaranteed Homo sapiens c-abl oncogene 1, non-receptor tyrosine kinase cDNA clone.

Type:
cDNA
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
Gene ID:
25 (Human, ABL1)
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Cloning Vector
Vector backbone:
pCR4-TOPO
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin

Sequencing Primer:
  • T7
  • T3
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3998307
$154.44
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
Supplier: Log in to see

Entry clone of human cDNA (ORF) without STOP codon in Gateway pDONR223 Vector.

Type:
ORF
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
Gene ID:
25 (Human, ABL1)
Synonyms:
ABL1, Abl1, abl-1, abl1
Insert length:
3450 bp
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin

Sequencing Primer:
  • Forward primer M13R (5'→3'): GTAAAACGACGGCCAGT
  • Reverse primer T7P (5'→3'): TAATACGACTCACTATAGG
Components:
2 μg of lyophilized gene in pDONR223 vector
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5324239
$224.73
2 μg
Plus shipping costs $45.00
Delivery in 15 to 17 Business Days
Supplier: Log in to see

ORF Cloning-Vector holds the gene between an AflII and EcoRV cut site.

Type:
ORF
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_007313
Species:
Human
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient

Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Catalog No. ABIN5746582
$375.00
1 μg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
Supplier: Log in to see

Individual gRNA against Abl1 in Lentiviral Particles with a Titer of >1x10e7 IU/mL. (Cas9 required separately)

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_001100850
Species:
Rat (Rattus)
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abl1
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5130166
$420.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available
Supplier: Log in to see

Individual gRNA against ABL1 in Lentiviral Particles with a Titer of >1x10e7 IU/mL. (Cas9 required separately)

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_005157
Species:
Human
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABL1
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5130162
$420.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available
Supplier: Log in to see

Individual gRNA against Abl1 in Lentiviral Particles with a Titer of >1x10e7 IU/mL. (Cas9 required separately)

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_009594
Species:
Mouse (Murine)
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abl1
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5130164
$420.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available
Supplier: Log in to see

siRNA (27 mer) kit with 3 gene-specific unique siRNA duplexes and negative control for gene knockdown.

Application:
RNA Interference
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase
Species:
Mouse (Murine)
Synonyms:
ABL, JTK7, bcr/abl, c-ABL, p150, v-abl, AI325092, Abl, E430008G22Rik, c-Abl
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • Abl1 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3349062
$420.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days
Supplier: Log in to see

ORF Cloning-Vector holds the gene between an AflII and EcoRV cut site.

Type:
ORF
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_009594
Species:
Mouse (Murine)
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient

Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Catalog No. ABIN5746583
$475.00
1 μg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
Supplier: Log in to see

ORF Cloning-Vector holds the gene between an AflII and EcoRV cut site.

Type:
ORF
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_001100850
Species:
Rat (Rattus)
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient

Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Catalog No. ABIN5746585
$475.00
1 μg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
Supplier: Log in to see

ORF Cloning-Vector holds the gene between an AflII and EcoRV cut site.

Type:
ORF
Application:
Cloning
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_001112703
Species:
Mouse (Murine)
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient

Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Catalog No. ABIN5746584
$475.00
1 μg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
Supplier: Log in to see

siRNA to inhibit ABL1 expression using RNA interference.

Application:
RNA Interference
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase
Gene ID:
11350 (Mouse (Murine), ABL1)
Synonyms:
ABL, JTK7, bcr/abl, c-ABL, p150, v-abl, AI325092, Abl, E430008G22Rik, c-Abl
Purification:
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Components:
This product is provided as two 5 nmol vials (10 nmol), three 5 nmol vials (15 nmol) or 2x three 5 nmol vials (30 nmol) of lyophilized siRNA oligo duplexes. Each vial contains slightly different sequences to ensure full knockout of the gene. Each vial contains slightly different sequences to ensure full knockout of the gene. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. The siRNA oligos are also chemically modified (2'-OMe) for increased stability and enhanced knockdown in vitro and in vivo.
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5793882
$516.85
Plus shipping costs $45.00
Delivery in 16 to 26 Business Days
Supplier: Log in to see

siRNA to inhibit ABL1 expression using RNA interference.

Application:
RNA Interference
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase
Gene ID:
25 (Human, ABL1)
Synonyms:
ABL, JTK7, bcr/abl, c-ABL, p150, v-abl, AI325092, Abl, E430008G22Rik, c-Abl
Purification:
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Components:
This product is provided as two 5 nmol vials (10 nmol), three 5 nmol vials (15 nmol) or 2x three 5 nmol vials (30 nmol) of lyophilized siRNA oligo duplexes. Each vial contains slightly different sequences to ensure full knockout of the gene. Each vial contains slightly different sequences to ensure full knockout of the gene. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. The siRNA oligos are also chemically modified (2'-OMe) for increased stability and enhanced knockdown in vitro and in vivo.
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5793883
$516.85
Plus shipping costs $45.00
Delivery in 16 to 26 Business Days
Supplier: Log in to see

transEDIT-dual CRISPR target gene set - with 3 vectors containing two gRNAs in each vector plus a negative control (glycerol stock)

Type:
gRNA + gRNA
Application:
Genome Editing with Engineered Nucleases
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
Gene ID:
25 (Human, ABL1)
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Lentiviral Vector
Vector backbone:
pCLIP-dual-SFFV-ZsGreen
Resistance Gene:
Ampicillin, Zeocin
Selection Marker:
Puromycin
Promoter:
SFFV Promoter, U6 Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Viral particles:
ABIN5052322

Components:
- Two vectors containing two gRNAs in each vector
- Negative control
- Available as bacterial glycerol stocks or viral particles
- Cas9 expression vectors can be purchased separately
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN5033377
$495.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days
Supplier: Log in to see

Individual gRNA against Abl1 in Lentiviral Particles with a Titer of >1x10e7 IU/mL. (sgRNA and Cas9 in a single vector)

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_009594
Species:
Mouse (Murine)
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abl1
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5245599
$520.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available
Supplier: Log in to see

Individual gRNA against ABL1 in Lentiviral Particles with a Titer of >1x10e7 IU/mL. (sgRNA and Cas9 in a single vector)

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
NCBI Accession:
NM_005157
Species:
Human
Synonyms:
ABL1, Abl1, abl-1, abl1
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABL1
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5245597
$520.00
300 μL
Plus shipping costs $45.00 and $22.60 dry ice
Available
  • <
  • 1

Synonyms and alternative names related to ABL1

  • ABL proto-oncogene 1, non-receptor tyrosine kinase (ABL1)
  • c-abl oncogene 1, non-receptor tyrosine kinase (Abl1)
  • ABL proto-oncogene 1, non-receptor tyrosine kinase (Abl1)
  • Tyrosine-protein kinase abl-1 (abl-1)
  • c-abl oncogene 1, non-receptor tyrosine kinase (abl1)
  • ABL
  • Abl
  • AI325092
  • bcr/abl
  • c-ABL
  • c-Abl
  • E430008G22Rik
  • JTK7
  • p150
  • v-abl

Gene-IDs for different species

GENE IDSPECIES
25 Homo sapiens
11350 Mus musculus
417181 Gallus gallus
464802 Pan troglodytes
491292 Canis lupus familiaris
311860 Rattus norvegicus
540876 Bos taurus
181261 Caenorhabditis elegans
100000720 Danio rerio

Protein level used designations for ABL1

  • Abelson tyrosine-protein kinase 1
  • bcr/c-abl oncogene protein
  • c-abl oncogene 1, receptor tyrosine kinase
  • proto-oncogene c-Abl
  • proto-oncogene tyrosine-protein kinase ABL1
  • tyrosine-protein kinase ABL1
  • v-abl Abelson murine leukemia viral oncogene homolog 1
  • Abelson murine leukemia oncogene
  • abelson murine leukemia viral oncogene homolog 1
  • p150
  • v-abl Abelson murine leukemia oncogene 1
  • Abelson murine leukemia viral (v-abl) oncogene homolog 1
  • v-abl Abelson murine leukemia viral oncogene 1
Other products related to ABL1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com