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APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans), APH1A)

Short Description: This gene encodes a component of the gamma secretase complex that cleaves integral membrane proteins such as Notch receptors and beta-amyloid precursor protein. The gamma secretase complex contains this gene product, or the paralogous anterior pharynx defective 1 homolog B (APH1B), along with the presenilin, nicastrin, and presenilin enhancer-2 proteins. The precise function of this seven-transmembrane-domain protein is unknown though it is suspected of facilitating the association of nicastrin and presenilin in the gamma secretase complex as well as interacting with substrates of the gamma secretase complex prior to their proteolytic processing. Polymorphisms in a promoter region of this gene have been associated with an increased risk for developing sporadic Alzheimer's disease. Alternative splicing results in multiple protein-coding and non-protein-coding transcript variants. [provided by RefSeq, Aug 2011].
More information related to gene APH1A.

Products related to APH1A Gene:

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91 results

Human APH1A cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4758500
$805.29
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
Details
Details
Human APH1A cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4758499
$805.29
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
Details
Details
Human APH1A cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4826579
$805.29
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
Details
Details
Human APH1A cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4826578
$805.29
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
Details
Details
Human APH1A cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4826577
$805.29
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
Details
Details
Human APH1A cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4697449
$805.29
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
Details
Details
Human APH1A cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4697448
$805.29
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
Details
Details
Human APH1A cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4433220
$805.29
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
Details
Details
Human APH1A cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4433219
$805.29
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
Details
Details
Human APH1A cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4433221
$805.29
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
    • pDONR223
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-XL4
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to APH1A

  • aph-1 homolog A, gamma-secretase subunit (APH1A)
  • aph-1 homolog A, gamma secretase subunit L homeolog (aph1a.L)
  • aph-1 homolog A, gamma secretase subunit (Aph1a)
  • anterior pharynx defective 1 homolog A (C. elegans) (APH1A)
  • aph1 homolog A, gamma secretase subunit (Aph1a)
  • acylamino-acid-releasing enzyme-like (LOC100219182)
  • 6530402N02Rik
  • APH-1
  • APH-1A
  • APH-1a
  • CGI-78
  • RGD1311546

Gene-IDs for different species

Protein level used designations for APH1A

  • anterior pharynx defective 1 homolog A
  • aph-1alpha
  • gamma-secretase subunit APH-1A
  • presenilin-stabilization factor
  • anterior pharynx defective 1a homolog
  • N-acylaminoacyl-peptide hydrolase
Other products related to APH1A such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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