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GCLM (Glutamate-Cysteine Ligase, Modifier Subunit, GCLM)

Short Description: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq, Jul 2008].
More information related to gene GCLM.

Products related to GCLM Gene:

58 results :

Human GCLM ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5750492
Datasheet
Catalog No. ABIN5750492
Type:
ORF
Application:
Cloning
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
Species:
Human
Synonyms:
PTRG_09814, Gclm, GCLM, gclm, gclm.L
Insert length:
825 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human GCLM cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4475955
Datasheet
Catalog No. ABIN4475955
Type:
cDNA
Application:
Protein Expression
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
Species:
Human
Synonyms:
PTRG_09814, Gclm, GCLM, gclm, gclm.L
Insert length:
825 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse GCLM CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
NCBI Accession:
NM_008129
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5253403
Datasheet
Catalog No. ABIN5253403
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
NCBI Accession:
NM_008129
Species:
Mouse
Synonyms:
PTRG_09814, Gclm, GCLM, gclm, gclm.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Gclm
Format:
Viral Particles
Storage:
-80 °C
Human GCLM CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
NCBI Accession:
NM_002061
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5253401
Datasheet
Catalog No. ABIN5253401
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
NCBI Accession:
NM_002061
Species:
Human
Synonyms:
PTRG_09814, Gclm, GCLM, gclm, gclm.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of GCLM
Format:
Viral Particles
Storage:
-80 °C
Rat GCLM CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
NCBI Accession:
NM_017305
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5253405
Datasheet
Catalog No. ABIN5253405
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
NCBI Accession:
NM_017305
Species:
Rat
Synonyms:
PTRG_09814, Gclm, GCLM, gclm, gclm.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Gclm
Format:
Viral Particles
Storage:
-80 °C
Rat GCLM CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
NCBI Accession:
NM_017305
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5137932
Datasheet
Catalog No. ABIN5137932
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
NCBI Accession:
NM_017305
Species:
Rat
Synonyms:
PTRG_09814, Gclm, GCLM, gclm, gclm.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Gclm
Format:
Viral Particles
Storage:
-80 °C
Human GCLM CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
NCBI Accession:
NM_002061
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5137928
Datasheet
Catalog No. ABIN5137928
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
NCBI Accession:
NM_002061
Species:
Human
Synonyms:
PTRG_09814, Gclm, GCLM, gclm, gclm.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of GCLM
Format:
Viral Particles
Storage:
-80 °C
Mouse GCLM CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
NCBI Accession:
NM_008129
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5137930
Datasheet
Catalog No. ABIN5137930
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
NCBI Accession:
NM_008129
Species:
Mouse
Synonyms:
PTRG_09814, Gclm, GCLM, gclm, gclm.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Gclm
Format:
Viral Particles
Storage:
-80 °C
Human GCLM cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4762330
Datasheet
Catalog No. ABIN4762330
Type:
cDNA
Application:
Cloning
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
Species:
Human
Synonyms:
PTRG_09814, Gclm, GCLM, gclm, gclm.L
Insert length:
825 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human GCLM cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4832020
Datasheet
Catalog No. ABIN4832020
Type:
cDNA
Application:
Cloning
Gene:
Glutamate-Cysteine Ligase, Modifier Subunit (GCLM)
Species:
Human
Synonyms:
PTRG_09814, Gclm, GCLM, gclm, gclm.L
Insert length:
825 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to GCLM

  • glutamate-cysteine ligase regulatory subunit (PTRG_09814)
  • glutamate cysteine ligase, modifier subunit (Gclm)
  • glutamate-cysteine ligase modifier subunit (GCLM)
  • glutamate-cysteine ligase, modifier subunit (gclm)
  • glutamate-cysteine ligase, modifier subunit L homeolog (gclm.L)
  • glutamate-cysteine ligase, modifier subunit (Gclm)
  • glutamate-cysteine ligase modifier subunit (Gclm)
  • AI649393
  • Gcmc
  • Glclr
  • GLCLR
  • id:ibd3182
  • wu:fi24c07
  • zgc:55903

Gene-IDs for different species

Protein level used designations for GCLM

  • glutamate-cysteine ligase regulatory subunit
  • GCS light chain
  • gamma-ECS regulatory subunit
  • gamma-glutamylcysteine synthetase regulatory subunit
  • glutamate cysteine ligase (gamma-glutamylcysteine synthetase), regulatory
  • glutamate--cysteine ligase regulatory subunit
  • glutamate-cysteine ligase modifier subunit
  • GSC light chain
  • glutamate--cysteine ligase modifier subunit
  • glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD)
  • glutamate-cysteine ligase modifier subunit delta2 alternative splicing
  • glutamate-cysteine ligase regulatory protein
Other products related to GCLM such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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