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TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein, TIRAP)

Short Description: The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants\; however, not all variants have been fully described. [provided by RefSeq, Jul 2008].
More information related to gene TIRAP.

Products related to TIRAP Gene:

54 results :

Human TIRAP ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5744072
Datasheet
Catalog No. ABIN5744072
Type:
ORF
Application:
Cloning
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
Species:
Human
Synonyms:
tirap, TIRAP, tirap.L, Tirap
Insert length:
771 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human TIRAP cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4482128
Datasheet
Catalog No. ABIN4482128
Type:
cDNA
Application:
Protein Expression
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
Species:
Human
Synonyms:
tirap, TIRAP, tirap.L, Tirap
Insert length:
771 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse TIRAP CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
NCBI Accession:
NM_054096
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5240937
Datasheet
Catalog No. ABIN5240937
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
NCBI Accession:
NM_054096
Species:
Mouse
Synonyms:
tirap, TIRAP, tirap.L, Tirap
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tirap
Format:
Viral Particles
Storage:
-80 °C
Human TIRAP CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
NCBI Accession:
NM_001039661
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5240935
Datasheet
Catalog No. ABIN5240935
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
NCBI Accession:
NM_001039661
Species:
Human
Synonyms:
tirap, TIRAP, tirap.L, Tirap
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of TIRAP
Format:
Viral Particles
Storage:
-80 °C
Mouse TIRAP CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
NCBI Accession:
NM_054096
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5125532
Datasheet
Catalog No. ABIN5125532
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
NCBI Accession:
NM_054096
Species:
Mouse
Synonyms:
tirap, TIRAP, tirap.L, Tirap
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tirap
Format:
Viral Particles
Storage:
-80 °C
Human TIRAP CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
NCBI Accession:
NM_001039661
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5125530
Datasheet
Catalog No. ABIN5125530
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
NCBI Accession:
NM_001039661
Species:
Human
Synonyms:
tirap, TIRAP, tirap.L, Tirap
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of TIRAP
Format:
Viral Particles
Storage:
-80 °C
Human TIRAP cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4841739
Datasheet
Catalog No. ABIN4841739
Type:
cDNA
Application:
Cloning
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
Species:
Human
Synonyms:
tirap, TIRAP, tirap.L, Tirap
Insert length:
771 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human TIRAP cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4625599
Datasheet
Catalog No. ABIN4625599
Type:
cDNA
Application:
Cloning
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
Species:
Human
Synonyms:
tirap, TIRAP, tirap.L, Tirap
Insert length:
771 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human TIRAP cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4712608
Datasheet
Catalog No. ABIN4712608
Type:
cDNA
Application:
Cloning
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
Species:
Human
Synonyms:
tirap, TIRAP, tirap.L, Tirap
Insert length:
771 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human TIRAP cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4417042
Datasheet
Catalog No. ABIN4417042
Type:
cDNA
Application:
Protein Expression
Gene:
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP)
Species:
Human
Synonyms:
tirap, TIRAP, tirap.L, Tirap
Insert length:
771 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to TIRAP

  • toll-interleukin 1 receptor (TIR) domain containing adaptor protein (tirap)
  • TIR domain containing adaptor protein (TIRAP)
  • toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog (tirap.L)
  • TIR domain containing adaptor protein (Tirap)
  • toll-interleukin 1 receptor (TIR) domain-containing adaptor protein (Tirap)
  • AA407980
  • BACTS1
  • C130027E04Rik
  • mal
  • Mal
  • MyD88-2
  • Tlr4ap
  • wyatt
  • Wyatt

Gene-IDs for different species

Protein level used designations for TIRAP

  • MyD88 adapter-like protein
  • Toll-interleukin 1 receptor domain-containing adaptor protein
  • toll/interleukin-1 receptor domain-containing adapter protein
  • TIR domain-containing adaptor protein
  • Toll-like receptor adaptor protein
  • adapter protein wyatt
  • adaptor protein Wyatt
  • toll-interleukin 1 receptor domain-containing adaptor protein
  • TIR domain-containing adapter protein
  • Toll-like receptor 4 adaptor protein
  • myD88 adapter-like protein
Other products related to TIRAP such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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