ABCC11 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11, ABCC11)

Short Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008].
More information related to gene ABCC11.
Products related to ABCC11 Gene:
49 Products
Type
  • 47
  • 2
Species
  • 49
Oligo-Type
  • 2
Insert
  • 23
  • 10
  • 7
  • 3
  • 2
Vector
  • 20
  • 16
  • 4
  • 3
  • 3
Vector Backbone
  • 5
  • 5
  • 4
  • 3
  • 2
Fusion tag
  • 13
  • 11
  • 9
  • 4
  • 3
Resistance Gene
  • 17
  • 14
  • 12
  • 4
  • 2
Selectable Marker
  • 14
  • 10
  • 1
Promoter
  • 23
  • 12
  • 5
  • 4
  • 4
Expression Type
  • 44
  • 24
Application
  • 31
  • 9
  • 7
  • 6
Format
  • 25
  • 10
  • 9
  • 5
Supplier: Log in to see

ORF Cloning-Vector holds the gene between an AflII and EcoRV cut site.

Type:
ORF
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Species:
Human
Synonyms:
ABCC11
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient

Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Catalog No. ABIN5743549
€39.82
1 μg
Plus shipping costs €45.00
Delivery in 3 to 4 Business Days
Supplier: Log in to see

Entry clone of human cDNA (ORF) without STOP codon in Gateway pDONR223 Vector.

Type:
ORF
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Gene ID:
85320 (Human, ABCC11)
Synonyms:
ABCC11
Insert length:
1662 bp
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin

Sequencing Primer:
  • Forward primer M13R (5'→3'): GTAAAACGACGGCCAGT
  • Reverse primer T7P (5'→3'): TAATACGACTCACTATAGG
Components:
2 μg of lyophilized gene in pDONR223 vector
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5317755
€181.06
2 μg
Plus shipping costs €45.00
Delivery in 15 to 17 Business Days
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Bacterial expression of Human ABCC11 with His-MBP

Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Species:
Human
Synonyms:
ABCC11
Insert length:
1662 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient

Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4696789
€243.36
500 ng
Plus shipping costs €45.00
Delivery in 11 to 21 Business Days
Supplier: Log in to see

Bacterial expression of Human ABCC11 with His-GST

Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Species:
Human
Synonyms:
ABCC11
Insert length:
1662 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient

Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4825918
€243.36
500 ng
Plus shipping costs €45.00
Delivery in 11 to 21 Business Days
Supplier: Log in to see

Bacterial expression of Human ABCC11 with His tag

Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Species:
Human
Synonyms:
ABCC11
Insert length:
1662 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient

Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4758024
€243.36
500 ng
Plus shipping costs €45.00
Delivery in 11 to 21 Business Days
Supplier: Log in to see

Mammalian expression of Human ABCC11 with HA tag

Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Species:
Human
Synonyms:
ABCC11
Insert length:
1662 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient

Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4372547
€243.36
500 ng
Plus shipping costs €45.00
Delivery in 11 to 21 Business Days
Supplier: Log in to see

Bacterial expression of Human ABCC11 with His tag

Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Species:
Human
Synonyms:
ABCC11
Insert length:
1662 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-C-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient

Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4372116
€243.36
500 ng
Plus shipping costs €45.00
Delivery in 11 to 21 Business Days
Supplier: Log in to see

Mammalian expression of Human ABCC11 with His tag

Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Species:
Human
Synonyms:
ABCC11
Insert length:
1662 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient

Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4432744
€243.36
500 ng
Plus shipping costs €45.00
Delivery in 11 to 21 Business Days
Supplier: Log in to see

The ATP-binding cassette, sub-family C (CFTR/MRP), member 11 ORF clone is provided in a Gateway adapted entry vector for fast and convenient transfer to any compatible expression vector.

Type:
ORF
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Gene ID:
85320 (Human, ABCC11)
Synonyms:
ABCC11
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin

Sequencing Primer:
  • M13pUC-fwd
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3412102
€265.49
1 vial
Plus shipping costs €45.00
Delivery in 6 to 8 Business Days
Supplier: Log in to see

The ATP-binding cassette, sub-family C (CFTR/MRP), member 11 ORF clone is provided in a Gateway adapted entry vector for fast and convenient transfer to any compatible expression vector.

Type:
ORF
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Gene ID:
85320 (Human, ABCC11)
Synonyms:
ABCC11
Vector type:
Gateway Cloning Vector
Vector backbone:
pENTR223-1
Resistance Gene:
Spectinomycin

Sequencing Primer:
  • T7
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3416465
€265.49
1 vial
Plus shipping costs €45.00
Delivery in 6 to 8 Business Days
Supplier: Log in to see

siRNA (27 mer) kit with 3 gene-specific unique siRNA duplexes and negative control for gene knockdown.

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11
Species:
Human
Synonyms:
EWWD, MRP8, WW
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • ABCC11 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3310833
€345.13
1 kit
Plus shipping costs €45.00
Will be delivered in 16 Business Days
Supplier: Log in to see

Individual gRNA against ABCC11 in Lentiviral Particles with a Titer of >1x10e7 IU/mL. (Cas9 required separately)

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
NCBI Accession:
NM_032583
Species:
Human
Synonyms:
ABCC11
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABCC11
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5124558
€349.56
300 μL
Plus shipping costs €45.00 and €20.00 dry ice
Available
Supplier: Log in to see

The lentiviral ATP-binding cassette, sub-family C (CFTR/MRP), member 11 ORF expression vector was created to enable expression of the protein with a V5 fusion tag.

Type:
ORF
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Gene ID:
85320 (Human, ABCC11)
Synonyms:
ABCC11
Vector type:
Lentiviral Vector
Vector backbone:
pLX304
Resistance Gene:
Ampicillin
Selection Marker:
Blasticidin
Promoter:
Enhanced CMV Promoter
Fusion Tag:
V5 tag
Expression:
Stable, Transient

Sequencing Primer:
  • 3-1291
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3400701
€398.23
1 vial
Plus shipping costs €45.00
Delivery in 6 to 8 Business Days
Supplier: Log in to see

siRNA to inhibit ABCC11 expression using RNA interference.

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11
Gene ID:
85320 (Human, ABCC11)
Synonyms:
EWWD, MRP8, WW
Purification:
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Components:
This product is provided as two 5 nmol vials (10 nmol), three 5 nmol vials (15 nmol) or 2x three 5 nmol vials (30 nmol) of lyophilized siRNA oligo duplexes. Each vial contains slightly different sequences to ensure full knockout of the gene. Each vial contains slightly different sequences to ensure full knockout of the gene. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. The siRNA oligos are also chemically modified (2'-OMe) for increased stability and enhanced knockdown in vitro and in vivo.
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5792447
€404.49
15 nmol
Plus shipping costs €45.00
Delivery in 16 to 26 Business Days
Supplier: Log in to see

Mammalian expression of Human ABCC11 with DYKDDDDK Tag,His tag

Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Species:
Human
Synonyms:
ABCC11
Insert length:
1662 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-N-D-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag,His tag
Expression:
Stable, Transient

Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4559203
€438.05
500 ng
Plus shipping costs €45.00
Delivery in 11 to 21 Business Days
Supplier: Log in to see

transEDIT-dual CRISPR target gene set - with 3 vectors containing two gRNAs in each vector plus a negative control (glycerol stock)

Type:
gRNA + gRNA
Application:
Genome Editing with Engineered Nucleases
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Gene ID:
85320 (Human, ABCC11)
Synonyms:
ABCC11
Vector type:
Lentiviral Vector
Vector backbone:
pCLIP-dual-SFFV-ZsGreen
Resistance Gene:
Ampicillin, Zeocin
Selection Marker:
Puromycin
Promoter:
SFFV Promoter, U6 Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Viral particles:
ABIN5064095

Components:
- Two vectors containing two gRNAs in each vector
- Negative control
- Available as bacterial glycerol stocks or viral particles
- Cas9 expression vectors can be purchased separately
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN5045150
€438.05
1 set
Plus shipping costs €45.00
Will be delivered in 16 Business Days
Supplier: Log in to see

Individual gRNA against ABCC11 in Lentiviral Particles with a Titer of >1x10e7 IU/mL. (sgRNA and Cas9 in a single vector)

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
NCBI Accession:
NM_032583
Species:
Human
Synonyms:
ABCC11
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABCC11
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5239961
€438.05
300 μL
Plus shipping costs €45.00 and €20.00 dry ice
Available
Supplier: Log in to see

Mammalian expression of Human ABCC11 with DYKDDDDK Tag,HA tag

Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Species:
Human
Synonyms:
ABCC11
Insert length:
1662 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-N-D-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag,HA tag
Expression:
Stable, Transient

Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4497994
€438.05
500 ng
Plus shipping costs €45.00
Delivery in 11 to 21 Business Days
Supplier: Log in to see

Pre-designed Hush-29 shRNAs in viral vectors with proven effectiveness for knock-down of Human ABCC11.

Type:
shRNA
Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Species:
Human
Synonyms:
ABCC11
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable

Empty vector controls:
ABIN4948187

Components:
  • Gene-specific shRNA in pGFPC-shLenti vector, 4 unique constructs per gene, 5 ug per vial.
  • HuSH 29-mer Scrambled in pGFP-C-shLenti 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3731804
€440.71
1 kit
Plus shipping costs €45.00
Delivery in 8 to 11 Business Days
Supplier: Log in to see

Pre-designed Hush-29 shRNAs in viral vectors with proven effectiveness for knock-down of Human ABCC11.

Type:
shRNA
Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11)
Species:
Human
Synonyms:
ABCC11
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable

Empty vector controls:
ABIN4948189

Components:
  • Gene-specific shRNA expression pRS vectors, 5 ug plasmid DNA per vial.
  • Four unique constructs per gene.
  • HuSH 29-mer NonEffective Scrambled pRS 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3648897
€575.22
1 kit
Plus shipping costs €45.00
Will be delivered in 16 Business Days
  • <
  • 1

Synonyms and alternative names related to ABCC11

  • ATP binding cassette subfamily C member 11 (ABCC11)
  • EWWD
  • MRP8
  • WW

Gene-IDs for different species

GENE IDSPECIES
85320 Homo sapiens

Protein level used designations for ABCC11

  • ATP-binding cassette protein C11
  • ATP-binding cassette sub-family C member 11
  • ATP-binding cassette transporter MRP8
  • ATP-binding cassette transporter sub-family C member 11
  • multi-resistance protein 8
  • multidrug resistance-associated protein 8
Other products related to ABCC11 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com