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APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2, APEX2)

Short Description: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012].
More information related to gene APEX2.

Products related to APEX2 Gene:

58 results

cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_001079892
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4382198
$1,441.35
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_029943
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4636949
$1,441.35
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_001079892
Species:
Rat
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4692388
$1,441.35
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_001079892
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5195585
$1,511.06
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 41 Business Days
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_014481
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5104546
$1,511.06
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 41 Business Days
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_029943
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5104548
$1,511.06
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 41 Business Days
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_001079892
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5311201
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 41 Business Days
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_014481
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5219805
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 41 Business Days
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_029943
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5219807
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 41 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_014481
Gene ID:
27301 (Human, APEX2)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4941536
$99.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 6 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL5
    • pDONR223
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to APEX2

  • apurinic/apyrimidinic endodeoxyribonuclease 2 (APEX2)
  • apurinic/apyrimidinic endodeoxyribonuclease 2 (apex2)
  • APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (apex2)
  • apurinic/apyrimidinic endodeoxyribonuclease 2 L homeolog (apex2.L)
  • APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2)
  • apurinic/apyrimidinic endonuclease 2 (Apex2)
  • apurinic/apyrimidinic endodeoxyribonuclease 2 (Apex2)
  • APE2
  • ape2
  • APEXL2
  • apexl2
  • C430040P13Rik
  • XTH2
  • xth2
  • zgc:55889

Gene-IDs for different species

Protein level used designations for APEX2

  • AP endonuclease 2
  • AP endonuclease XTH2
  • DNA-(apurinic or apyrimidinic site) lyase 2
  • apurinic/apyrimidinic endonuclease-like 2
  • APEX nuclease 2
  • apurinic-apyrimidinic endonuclease 2
  • APEX nuclease (apurinic/apyrimidinic endonuclease) 2
  • DNA-(apurinic or apyrimidinic site) lyase 2-like
Other products related to APEX2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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