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HLA-DMB (Major Histocompatibility Complex, Class II, DM beta, HLA-DMB)

Short Description: HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008].
More information related to gene HLA-DMB.

Products related to HLA-DMB Gene:

15 results :

Human HLA-DMB ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5731909
Datasheet
Catalog No. ABIN5731909
Type:
ORF
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
Species:
Human
Synonyms:
HLA-DMB, RT1-DMb, PATR-DMB
Insert length:
792 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human HLA-DMB cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4476561
Datasheet
Catalog No. ABIN4476561
Type:
cDNA
Application:
Protein Expression
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
Species:
Human
Synonyms:
HLA-DMB, RT1-DMb, PATR-DMB
Insert length:
792 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HLA-DMB CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
NCBI Accession:
NM_002118
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5102553
Datasheet
Catalog No. ABIN5102553
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
NCBI Accession:
NM_002118
Species:
Human
Synonyms:
HLA-DMB, RT1-DMb, PATR-DMB
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of HLA-DMB
Format:
Viral Particles
Storage:
-80 °C
Human HLA-DMB cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4832947
Datasheet
Catalog No. ABIN4832947
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
Species:
Human
Synonyms:
HLA-DMB, RT1-DMb, PATR-DMB
Insert length:
792 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HLA-DMB cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4762936
Datasheet
Catalog No. ABIN4762936
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
Species:
Human
Synonyms:
HLA-DMB, RT1-DMb, PATR-DMB
Insert length:
792 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HLA-DMB cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4703817
Datasheet
Catalog No. ABIN4703817
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
Species:
Human
Synonyms:
HLA-DMB, RT1-DMb, PATR-DMB
Insert length:
792 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HLA-DMB cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4437656
Datasheet
Catalog No. ABIN4437656
Type:
cDNA
Application:
Protein Expression
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
Species:
Human
Synonyms:
HLA-DMB, RT1-DMb, PATR-DMB
Insert length:
792 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HLA-DMB CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
NCBI Accession:
NM_002118
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5217806
Datasheet
Catalog No. ABIN5217806
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
NCBI Accession:
NM_002118
Species:
Human
Synonyms:
HLA-DMB, RT1-DMb, PATR-DMB
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of HLA-DMB
Format:
Viral Particles
Storage:
-80 °C
Human HLA-DMB CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
NCBI Accession:
NM_002118
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5102552
Datasheet
Catalog No. ABIN5102552
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
NCBI Accession:
NM_002118
Species:
Human
Synonyms:
HLA-DMB, RT1-DMb, PATR-DMB
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of HLA-DMB
Format:
Viral Particles
Storage:
-80 °C
Human HLA-DMB CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
NCBI Accession:
NM_002118
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5217805
Datasheet
Catalog No. ABIN5217805
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB)
NCBI Accession:
NM_002118
Species:
Human
Synonyms:
HLA-DMB, RT1-DMb, PATR-DMB
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of HLA-DMB
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • His tag
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag
    • GFP tag
    • HA tag
    • His-GST
    • His-MBP
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pDONR223
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • gRNA
    • gRNA + Cas9
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Liquid
    • Lyophilized
    • Viral Particles

Synonyms and alternative names related to HLA-DMB

  • major histocompatibility complex, class II, DM beta (HLA-DMB)
  • RT1 class II, locus DMb (RT1-DMb)
  • major histocompatibility complex, class II, DM beta (PATR-DMB)
  • D6S221E
  • MHC-DMB
  • RING7
  • RT1.DMb
  • RT1.Mb

Gene-IDs for different species

Protein level used designations for HLA-DMB

  • HLA class II histocompatibility antigen, DM beta chain
  • MHC class II HLA-DMB
  • MHC class II antigen DMB
  • MHC class II antigen HLA-DM beta chain
  • class II histocompatibility antigen, M beta chain
  • really interesting new gene 7 protein
  • MHC class II-like beta chain
  • RT1 class II, DM beta
  • major histocompatibility complex, class II, DM beta
Other products related to HLA-DMB such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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